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7Z8Q

Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core

Functional Information from GO Data
ChainGOidnamespacecontents
a0003677molecular_functionDNA binding
a0003899molecular_functionDNA-directed RNA polymerase activity
a0005737cellular_componentcytoplasm
a0005829cellular_componentcytosol
a0005886cellular_componentplasma membrane
a0006351biological_processDNA-templated transcription
a0034062molecular_function5'-3' RNA polymerase activity
a0046983molecular_functionprotein dimerization activity
b0003677molecular_functionDNA binding
b0003899molecular_functionDNA-directed RNA polymerase activity
b0005737cellular_componentcytoplasm
b0005829cellular_componentcytosol
b0005886cellular_componentplasma membrane
b0006351biological_processDNA-templated transcription
b0034062molecular_function5'-3' RNA polymerase activity
b0046983molecular_functionprotein dimerization activity
c0000345cellular_componentcytosolic DNA-directed RNA polymerase complex
c0003677molecular_functionDNA binding
c0003899molecular_functionDNA-directed RNA polymerase activity
c0005515molecular_functionprotein binding
c0005829cellular_componentcytosol
c0005886cellular_componentplasma membrane
c0006351biological_processDNA-templated transcription
c0006352biological_processDNA-templated transcription initiation
c0006354biological_processDNA-templated transcription elongation
c0032549molecular_functionribonucleoside binding
c0034062molecular_function5'-3' RNA polymerase activity
d0000287molecular_functionmagnesium ion binding
d0003677molecular_functionDNA binding
d0003899molecular_functionDNA-directed RNA polymerase activity
d0005829cellular_componentcytosol
d0005886cellular_componentplasma membrane
d0006351biological_processDNA-templated transcription
d0008270molecular_functionzinc ion binding
d0034062molecular_function5'-3' RNA polymerase activity
e0000345cellular_componentcytosolic DNA-directed RNA polymerase complex
e0001000molecular_functionbacterial-type RNA polymerase core enzyme binding
e0003677molecular_functionDNA binding
e0003899molecular_functionDNA-directed RNA polymerase activity
e0005829cellular_componentcytosol
e0006351biological_processDNA-templated transcription
e0006352biological_processDNA-templated transcription initiation
e0034062molecular_function5'-3' RNA polymerase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues11
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

254587

PDB entries from 2026-06-03

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