7Z4Z
Human NEXT dimer - focused reconstruction of the dimerization module
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000176 | cellular_component | nuclear exosome (RNase complex) |
| B | 0000178 | cellular_component | exosome (RNase complex) |
| B | 0000398 | biological_process | mRNA splicing, via spliceosome |
| B | 0000460 | biological_process | maturation of 5.8S rRNA |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003724 | molecular_function | RNA helicase activity |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005681 | cellular_component | spliceosomal complex |
| B | 0005730 | cellular_component | nucleolus |
| B | 0006364 | biological_process | rRNA processing |
| B | 0006397 | biological_process | mRNA processing |
| B | 0006401 | biological_process | RNA catabolic process |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008380 | biological_process | RNA splicing |
| B | 0016076 | biological_process | snRNA catabolic process |
| B | 0016607 | cellular_component | nuclear speck |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0031499 | cellular_component | TRAMP complex |
| B | 0071013 | cellular_component | catalytic step 2 spliceosome |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000176 | cellular_component | nuclear exosome (RNase complex) |
| D | 0000178 | cellular_component | exosome (RNase complex) |
| D | 0000398 | biological_process | mRNA splicing, via spliceosome |
| D | 0000460 | biological_process | maturation of 5.8S rRNA |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003724 | molecular_function | RNA helicase activity |
| D | 0004386 | molecular_function | helicase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005681 | cellular_component | spliceosomal complex |
| D | 0005730 | cellular_component | nucleolus |
| D | 0006364 | biological_process | rRNA processing |
| D | 0006397 | biological_process | mRNA processing |
| D | 0006401 | biological_process | RNA catabolic process |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008380 | biological_process | RNA splicing |
| D | 0016076 | biological_process | snRNA catabolic process |
| D | 0016607 | cellular_component | nuclear speck |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0031499 | cellular_component | TRAMP complex |
| D | 0071013 | cellular_component | catalytic step 2 spliceosome |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
