Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7Z0O

Structure of transcription factor UAF in complex with TBP and 35S rRNA promoter DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000500	cellular_component	RNA polymerase I upstream activating factor complex
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0006325	biological_process	chromatin organization
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006878	biological_process	intracellular copper ion homeostasis
A	0008823	molecular_function	cupric reductase (NADH) activity
A	0009060	biological_process	aerobic respiration
A	0009303	biological_process	rRNA transcription
A	0030527	molecular_function	structural constituent of chromatin
A	0031298	cellular_component	replication fork protection complex
A	0032991	cellular_component	protein-containing complex
A	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
A	0043505	cellular_component	CENP-A containing nucleosome
A	0043935	biological_process	sexual sporulation resulting in formation of a cellular spore
A	0045943	biological_process	positive regulation of transcription by RNA polymerase I
A	0046982	molecular_function	protein heterodimerization activity
A	0070911	biological_process	global genome nucleotide-excision repair
B	0000500	cellular_component	RNA polymerase I upstream activating factor complex
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0006355	biological_process	regulation of DNA-templated transcription
B	0030527	molecular_function	structural constituent of chromatin
B	0031298	cellular_component	replication fork protection complex
B	0032991	cellular_component	protein-containing complex
B	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
B	0042802	molecular_function	identical protein binding
B	0045943	biological_process	positive regulation of transcription by RNA polymerase I
B	0046982	molecular_function	protein heterodimerization activity
C	0000500	cellular_component	RNA polymerase I upstream activating factor complex
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0006325	biological_process	chromatin organization
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006878	biological_process	intracellular copper ion homeostasis
C	0008823	molecular_function	cupric reductase (NADH) activity
C	0009060	biological_process	aerobic respiration
C	0009303	biological_process	rRNA transcription
C	0030527	molecular_function	structural constituent of chromatin
C	0031298	cellular_component	replication fork protection complex
C	0032991	cellular_component	protein-containing complex
C	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
C	0043505	cellular_component	CENP-A containing nucleosome
C	0043935	biological_process	sexual sporulation resulting in formation of a cellular spore
C	0045943	biological_process	positive regulation of transcription by RNA polymerase I
C	0046982	molecular_function	protein heterodimerization activity
C	0070911	biological_process	global genome nucleotide-excision repair
D	0000500	cellular_component	RNA polymerase I upstream activating factor complex
D	0001181	molecular_function	RNA polymerase I general transcription initiation factor activity
D	0005634	cellular_component	nucleus
D	0005730	cellular_component	nucleolus
D	0006325	biological_process	chromatin organization
D	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
D	0045943	biological_process	positive regulation of transcription by RNA polymerase I
E	0000500	cellular_component	RNA polymerase I upstream activating factor complex
E	0001181	molecular_function	RNA polymerase I general transcription initiation factor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005730	cellular_component	nucleolus
E	0017025	molecular_function	TBP-class protein binding
E	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
E	0045943	biological_process	positive regulation of transcription by RNA polymerase I
F	0000500	cellular_component	RNA polymerase I upstream activating factor complex
F	0001165	molecular_function	RNA polymerase I cis-regulatory region sequence-specific DNA binding
F	0001181	molecular_function	RNA polymerase I general transcription initiation factor activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005730	cellular_component	nucleolus
F	0006360	biological_process	transcription by RNA polymerase I
F	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
F	0045943	biological_process	positive regulation of transcription by RNA polymerase I
G	0000500	cellular_component	RNA polymerase I upstream activating factor complex
G	0001165	molecular_function	RNA polymerase I cis-regulatory region sequence-specific DNA binding
G	0001181	molecular_function	RNA polymerase I general transcription initiation factor activity
G	0005634	cellular_component	nucleus
G	0005730	cellular_component	nucleolus
G	0006325	biological_process	chromatin organization
G	0006361	biological_process	transcription initiation at RNA polymerase I promoter
G	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
G	0045943	biological_process	positive regulation of transcription by RNA polymerase I
H	0000126	cellular_component	transcription factor TFIIIB complex
H	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
H	0001016	molecular_function	RNA polymerase III transcription regulatory region sequence-specific DNA binding
H	0001092	molecular_function	TFIIA-class transcription factor complex binding
H	0001179	molecular_function	RNA polymerase I general transcription initiation factor binding
H	0001188	biological_process	RNA polymerase I preinitiation complex assembly
H	0003677	molecular_function	DNA binding
H	0003682	molecular_function	chromatin binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005667	cellular_component	transcription regulator complex
H	0005669	cellular_component	transcription factor TFIID complex
H	0005672	cellular_component	transcription factor TFIIA complex
H	0006352	biological_process	DNA-templated transcription initiation
H	0006359	biological_process	regulation of transcription by RNA polymerase III
H	0008301	molecular_function	DNA binding, bending
H	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
H	0032991	cellular_component	protein-containing complex
H	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0045944	biological_process	positive regulation of transcription by RNA polymerase II
H	0051123	biological_process	RNA polymerase II preinitiation complex assembly
H	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
H	0070898	biological_process	RNA polymerase III preinitiation complex assembly
H	0097718	molecular_function	disordered domain specific binding
H	0140297	molecular_function	DNA-binding transcription factor binding

Functional Information from PROSITE/UniProt

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY15-HIS19

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
A	LYS15-LEU21

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI

Chain	Residue	Details
H	TYR94-ILE143
H	TYR185-LEU234

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
A	PRO67-ILE75

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17330950

Chain	Residue	Details
G	SER218
G	SER220
G	SER223

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269\|PubMed:22343720

Chain	Residue	Details
B	LYS6
B	LYS9
B	LYS13
C	LYS10
C	LYS19
C	LYS28

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269\|PubMed:11080160, ECO:0000269\|PubMed:15150415, ECO:0000269\|PubMed:17289592, ECO:0000269\|PubMed:19113941

Chain	Residue	Details
B	LYS17
C	SER11

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000269\|PubMed:22389435

Chain	Residue	Details
B	LYS32
B	LYS78

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine => ECO:0000269\|PubMed:19113941

Chain	Residue	Details
B	ARG56
A	LYS57
C	LYS24
C	LYS57

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18407956, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
B	SER61
C	LYS37

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17287358, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
B	SER65
C	LYS38

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269\|PubMed:16768447

Chain	Residue	Details
B	LYS80
C	LYS65

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: N6-glutaryllysine => ECO:0000269\|PubMed:31542297

Chain	Residue	Details
B	LYS92
C	LYS80

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)