7YZF

Crystal structure of the human FoxA2 bound to the TGTTTATT site (forkhead motif ATAAACA)

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription
C	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00657
Number of Residues	14
Details	FORK_HEAD_1 Fork head domain signature 1. KPPYSYisLitm.AI

Chain	Residue	Details
C	LYS159-ILE172

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site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WQNSIRH

Chain	Residue	Details
C	TRP203-HIS209

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P32182","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P32182","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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