Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7YWY

Structure of the GroEL chaperonin in complex with the CnoX chaperedoxin

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0000287	molecular_function	magnesium ion binding
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006457	biological_process	protein folding
b	0009314	biological_process	response to radiation
b	0009408	biological_process	response to heat
b	0016020	cellular_component	membrane
b	0016853	molecular_function	isomerase activity
b	0016887	molecular_function	ATP hydrolysis activity
b	0019068	biological_process	virion assembly
b	0042026	biological_process	protein refolding
b	0042802	molecular_function	identical protein binding
b	0051082	molecular_function	unfolded protein binding
b	0051085	biological_process	chaperone cofactor-dependent protein refolding
b	0140662	molecular_function	ATP-dependent protein folding chaperone
b	1990220	cellular_component	GroEL-GroES complex
G	0000287	molecular_function	magnesium ion binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006457	biological_process	protein folding
G	0009314	biological_process	response to radiation
G	0009408	biological_process	response to heat
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019068	biological_process	virion assembly
G	0042026	biological_process	protein refolding
G	0042802	molecular_function	identical protein binding
G	0051082	molecular_function	unfolded protein binding
G	0051085	biological_process	chaperone cofactor-dependent protein refolding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1990220	cellular_component	GroEL-GroES complex
H	0000287	molecular_function	magnesium ion binding
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006457	biological_process	protein folding
H	0009314	biological_process	response to radiation
H	0009408	biological_process	response to heat
H	0016020	cellular_component	membrane
H	0016853	molecular_function	isomerase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019068	biological_process	virion assembly
H	0042026	biological_process	protein refolding
H	0042802	molecular_function	identical protein binding
H	0051082	molecular_function	unfolded protein binding
H	0051085	biological_process	chaperone cofactor-dependent protein refolding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1990220	cellular_component	GroEL-GroES complex
I	0000287	molecular_function	magnesium ion binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006457	biological_process	protein folding
I	0009314	biological_process	response to radiation
I	0009408	biological_process	response to heat
I	0016020	cellular_component	membrane
I	0016853	molecular_function	isomerase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019068	biological_process	virion assembly
I	0042026	biological_process	protein refolding
I	0042802	molecular_function	identical protein binding
I	0051082	molecular_function	unfolded protein binding
I	0051085	biological_process	chaperone cofactor-dependent protein refolding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1990220	cellular_component	GroEL-GroES complex
J	0000287	molecular_function	magnesium ion binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006457	biological_process	protein folding
J	0009314	biological_process	response to radiation
J	0009408	biological_process	response to heat
J	0016020	cellular_component	membrane
J	0016853	molecular_function	isomerase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019068	biological_process	virion assembly
J	0042026	biological_process	protein refolding
J	0042802	molecular_function	identical protein binding
J	0051082	molecular_function	unfolded protein binding
J	0051085	biological_process	chaperone cofactor-dependent protein refolding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1990220	cellular_component	GroEL-GroES complex
K	0000287	molecular_function	magnesium ion binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006457	biological_process	protein folding
K	0009314	biological_process	response to radiation
K	0009408	biological_process	response to heat
K	0016020	cellular_component	membrane
K	0016853	molecular_function	isomerase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0019068	biological_process	virion assembly
K	0042026	biological_process	protein refolding
K	0042802	molecular_function	identical protein binding
K	0051082	molecular_function	unfolded protein binding
K	0051085	biological_process	chaperone cofactor-dependent protein refolding
K	0140662	molecular_function	ATP-dependent protein folding chaperone
K	1990220	cellular_component	GroEL-GroES complex
L	0000287	molecular_function	magnesium ion binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006457	biological_process	protein folding
L	0009314	biological_process	response to radiation
L	0009408	biological_process	response to heat
L	0016020	cellular_component	membrane
L	0016853	molecular_function	isomerase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0019068	biological_process	virion assembly
L	0042026	biological_process	protein refolding
L	0042802	molecular_function	identical protein binding
L	0051082	molecular_function	unfolded protein binding
L	0051085	biological_process	chaperone cofactor-dependent protein refolding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
L	1990220	cellular_component	GroEL-GroES complex
S	0000287	molecular_function	magnesium ion binding
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006457	biological_process	protein folding
S	0009314	biological_process	response to radiation
S	0009408	biological_process	response to heat
S	0016020	cellular_component	membrane
S	0016853	molecular_function	isomerase activity
S	0016887	molecular_function	ATP hydrolysis activity
S	0019068	biological_process	virion assembly
S	0042026	biological_process	protein refolding
S	0042802	molecular_function	identical protein binding
S	0051082	molecular_function	unfolded protein binding
S	0051085	biological_process	chaperone cofactor-dependent protein refolding
S	0140662	molecular_function	ATP-dependent protein folding chaperone
S	1990220	cellular_component	GroEL-GroES complex
T	0000287	molecular_function	magnesium ion binding
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006457	biological_process	protein folding
T	0009314	biological_process	response to radiation
T	0009408	biological_process	response to heat
T	0016020	cellular_component	membrane
T	0016853	molecular_function	isomerase activity
T	0016887	molecular_function	ATP hydrolysis activity
T	0019068	biological_process	virion assembly
T	0042026	biological_process	protein refolding
T	0042802	molecular_function	identical protein binding
T	0051082	molecular_function	unfolded protein binding
T	0051085	biological_process	chaperone cofactor-dependent protein refolding
T	0140662	molecular_function	ATP-dependent protein folding chaperone
T	1990220	cellular_component	GroEL-GroES complex
U	0000287	molecular_function	magnesium ion binding
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006457	biological_process	protein folding
U	0009314	biological_process	response to radiation
U	0009408	biological_process	response to heat
U	0016020	cellular_component	membrane
U	0016853	molecular_function	isomerase activity
U	0016887	molecular_function	ATP hydrolysis activity
U	0019068	biological_process	virion assembly
U	0042026	biological_process	protein refolding
U	0042802	molecular_function	identical protein binding
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0140662	molecular_function	ATP-dependent protein folding chaperone
U	1990220	cellular_component	GroEL-GroES complex
V	0000287	molecular_function	magnesium ion binding
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006457	biological_process	protein folding
V	0009314	biological_process	response to radiation
V	0009408	biological_process	response to heat
V	0016020	cellular_component	membrane
V	0016853	molecular_function	isomerase activity
V	0016887	molecular_function	ATP hydrolysis activity
V	0019068	biological_process	virion assembly
V	0042026	biological_process	protein refolding
V	0042802	molecular_function	identical protein binding
V	0051082	molecular_function	unfolded protein binding
V	0051085	biological_process	chaperone cofactor-dependent protein refolding
V	0140662	molecular_function	ATP-dependent protein folding chaperone
V	1990220	cellular_component	GroEL-GroES complex
W	0000287	molecular_function	magnesium ion binding
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006457	biological_process	protein folding
W	0009314	biological_process	response to radiation
W	0009408	biological_process	response to heat
W	0016020	cellular_component	membrane
W	0016853	molecular_function	isomerase activity
W	0016887	molecular_function	ATP hydrolysis activity
W	0019068	biological_process	virion assembly
W	0042026	biological_process	protein refolding
W	0042802	molecular_function	identical protein binding
W	0051082	molecular_function	unfolded protein binding
W	0051085	biological_process	chaperone cofactor-dependent protein refolding
W	0140662	molecular_function	ATP-dependent protein folding chaperone
W	1990220	cellular_component	GroEL-GroES complex
X	0000287	molecular_function	magnesium ion binding
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006457	biological_process	protein folding
X	0009314	biological_process	response to radiation
X	0009408	biological_process	response to heat
X	0016020	cellular_component	membrane
X	0016853	molecular_function	isomerase activity
X	0016887	molecular_function	ATP hydrolysis activity
X	0019068	biological_process	virion assembly
X	0042026	biological_process	protein refolding
X	0042802	molecular_function	identical protein binding
X	0051082	molecular_function	unfolded protein binding
X	0051085	biological_process	chaperone cofactor-dependent protein refolding
X	0140662	molecular_function	ATP-dependent protein folding chaperone
X	1990220	cellular_component	GroEL-GroES complex
Z	0000287	molecular_function	magnesium ion binding
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006457	biological_process	protein folding
Z	0009314	biological_process	response to radiation
Z	0009408	biological_process	response to heat
Z	0016020	cellular_component	membrane
Z	0016853	molecular_function	isomerase activity
Z	0016887	molecular_function	ATP hydrolysis activity
Z	0019068	biological_process	virion assembly
Z	0042026	biological_process	protein refolding
Z	0042802	molecular_function	identical protein binding
Z	0051082	molecular_function	unfolded protein binding
Z	0051085	biological_process	chaperone cofactor-dependent protein refolding
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	1990220	cellular_component	GroEL-GroES complex

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGVVaGGG

Chain	Residue	Details
b	ALA405-GLY416

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00600, ECO:0000269\|PubMed:25174333, ECO:0000305\|PubMed:14517228, ECO:0000305\|PubMed:9285585, ECO:0007744\|PDB:1AON, ECO:0007744\|PDB:1PCQ, ECO:0007744\|PDB:1PF9, ECO:0007744\|PDB:3WVL

Chain	Residue	Details
b	THR30
G	ASP495
H	THR30
H	ASP87
H	GLY415
H	ASN479
H	ASP495
I	THR30
I	ASP87
I	GLY415
I	ASN479
b	ASP87
I	ASP495
J	THR30
J	ASP87
J	GLY415
J	ASN479
J	ASP495
K	THR30
K	ASP87
K	GLY415
K	ASN479
b	GLY415
K	ASP495
L	THR30
L	ASP87
L	GLY415
L	ASN479
L	ASP495
Z	THR30
Z	ASP87
Z	GLY415
Z	ASN479
b	ASN479
Z	ASP495
S	THR30
S	ASP87
S	GLY415
S	ASN479
S	ASP495
T	THR30
T	ASP87
T	GLY415
T	ASN479
b	ASP495
T	ASP495
U	THR30
U	ASP87
U	GLY415
U	ASN479
U	ASP495
V	THR30
V	ASP87
V	GLY415
V	ASN479
G	THR30
V	ASP495
W	THR30
W	ASP87
W	GLY415
W	ASN479
W	ASP495
X	THR30
X	ASP87
X	GLY415
X	ASN479
G	ASP87
X	ASP495
G	GLY415
G	ASN479

site_id	SWS_FT_FI2
Number of Residues	14
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00600, ECO:0000269\|PubMed:25174333, ECO:0000305\|PubMed:14517228, ECO:0000305\|PubMed:9285585, ECO:0007744\|PDB:1AON, ECO:0007744\|PDB:1PF9, ECO:0007744\|PDB:3WVL

Chain	Residue	Details
b	LYS51
T	LYS51
U	LYS51
V	LYS51
W	LYS51
X	LYS51
G	LYS51
H	LYS51
I	LYS51
J	LYS51
K	LYS51
L	LYS51
Z	LYS51
S	LYS51

site_id	SWS_FT_FI3
Number of Residues	70
Details	MOD_RES: N6-succinyllysine => ECO:0000269\|PubMed:21151122

Chain	Residue	Details
b	LYS34
G	LYS390
H	LYS34
H	LYS51
H	LYS277
H	LYS321
H	LYS390
I	LYS34
I	LYS51
I	LYS277
I	LYS321
b	LYS51
I	LYS390
J	LYS34
J	LYS51
J	LYS277
J	LYS321
J	LYS390
K	LYS34
K	LYS51
K	LYS277
K	LYS321
b	LYS277
K	LYS390
L	LYS34
L	LYS51
L	LYS277
L	LYS321
L	LYS390
Z	LYS34
Z	LYS51
Z	LYS277
Z	LYS321
b	LYS321
Z	LYS390
S	LYS34
S	LYS51
S	LYS277
S	LYS321
S	LYS390
T	LYS34
T	LYS51
T	LYS277
T	LYS321
b	LYS390
T	LYS390
U	LYS34
U	LYS51
U	LYS277
U	LYS321
U	LYS390
V	LYS34
V	LYS51
V	LYS277
V	LYS321
G	LYS34
V	LYS390
W	LYS34
W	LYS51
W	LYS277
W	LYS321
W	LYS390
X	LYS34
X	LYS51
X	LYS277
X	LYS321
G	LYS51
X	LYS390
G	LYS277
G	LYS321

site_id	SWS_FT_FI4
Number of Residues	14
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269\|PubMed:21151122

Chain	Residue	Details
b	LYS117
T	LYS117
U	LYS117
V	LYS117
W	LYS117
X	LYS117
G	LYS117
H	LYS117
I	LYS117
J	LYS117
K	LYS117
L	LYS117
Z	LYS117
S	LYS117

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)