Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7YQC

EM structure of human PA28gamma

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000502	cellular_component	proteasome complex
A	0002039	molecular_function	p53 binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006915	biological_process	apoptotic process
A	0008537	cellular_component	proteasome activator complex
A	0016020	cellular_component	membrane
A	0042802	molecular_function	identical protein binding
A	0061133	molecular_function	endopeptidase activator activity
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	0097371	molecular_function	MDM2/MDM4 family protein binding
A	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
A	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
B	0000502	cellular_component	proteasome complex
B	0002039	molecular_function	p53 binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006915	biological_process	apoptotic process
B	0008537	cellular_component	proteasome activator complex
B	0016020	cellular_component	membrane
B	0042802	molecular_function	identical protein binding
B	0061133	molecular_function	endopeptidase activator activity
B	0061136	biological_process	regulation of proteasomal protein catabolic process
B	0097371	molecular_function	MDM2/MDM4 family protein binding
B	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
B	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
C	0000502	cellular_component	proteasome complex
C	0002039	molecular_function	p53 binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006915	biological_process	apoptotic process
C	0008537	cellular_component	proteasome activator complex
C	0016020	cellular_component	membrane
C	0042802	molecular_function	identical protein binding
C	0061133	molecular_function	endopeptidase activator activity
C	0061136	biological_process	regulation of proteasomal protein catabolic process
C	0097371	molecular_function	MDM2/MDM4 family protein binding
C	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
C	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
D	0000502	cellular_component	proteasome complex
D	0002039	molecular_function	p53 binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006915	biological_process	apoptotic process
D	0008537	cellular_component	proteasome activator complex
D	0016020	cellular_component	membrane
D	0042802	molecular_function	identical protein binding
D	0061133	molecular_function	endopeptidase activator activity
D	0061136	biological_process	regulation of proteasomal protein catabolic process
D	0097371	molecular_function	MDM2/MDM4 family protein binding
D	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
D	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
E	0000502	cellular_component	proteasome complex
E	0002039	molecular_function	p53 binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006915	biological_process	apoptotic process
E	0008537	cellular_component	proteasome activator complex
E	0016020	cellular_component	membrane
E	0042802	molecular_function	identical protein binding
E	0061133	molecular_function	endopeptidase activator activity
E	0061136	biological_process	regulation of proteasomal protein catabolic process
E	0097371	molecular_function	MDM2/MDM4 family protein binding
E	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
E	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
F	0000502	cellular_component	proteasome complex
F	0002039	molecular_function	p53 binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006915	biological_process	apoptotic process
F	0008537	cellular_component	proteasome activator complex
F	0016020	cellular_component	membrane
F	0042802	molecular_function	identical protein binding
F	0061133	molecular_function	endopeptidase activator activity
F	0061136	biological_process	regulation of proteasomal protein catabolic process
F	0097371	molecular_function	MDM2/MDM4 family protein binding
F	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
F	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway
G	0000502	cellular_component	proteasome complex
G	0002039	molecular_function	p53 binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006915	biological_process	apoptotic process
G	0008537	cellular_component	proteasome activator complex
G	0016020	cellular_component	membrane
G	0042802	molecular_function	identical protein binding
G	0061133	molecular_function	endopeptidase activator activity
G	0061136	biological_process	regulation of proteasomal protein catabolic process
G	0097371	molecular_function	MDM2/MDM4 family protein binding
G	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
G	2001237	biological_process	negative regulation of extrinsic apoptotic signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	MOD_RES: N-acetylalanine => ECO:0000269\|Ref.9, ECO:0007744\|PubMed:22814378

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2
E	ALA2
F	ALA2
G	ALA2

site_id	SWS_FT_FI2
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
A	SER17
B	SER17
C	SER17
D	SER17
E	SER17
F	SER17
G	SER17

site_id	SWS_FT_FI3
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
A	SER24
B	SER24
C	SER24
D	SER24
E	SER24
F	SER24
G	SER24

site_id	SWS_FT_FI4
Number of Residues	7
Details	MOD_RES: N6-acetyllysine; by P300/CBP => ECO:0000269\|PubMed:23612972

Chain	Residue	Details
A	LYS195
B	LYS195
C	LYS195
D	LYS195
E	LYS195
F	LYS195
G	LYS195

site_id	SWS_FT_FI5
Number of Residues	7
Details	MOD_RES: Phosphoserine; by CHEK2 => ECO:0000269\|PubMed:25361978

Chain	Residue	Details
A	SER247
B	SER247
C	SER247
D	SER247
E	SER247
F	SER247
G	SER247

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)