7YJK

Cryo-EM structure of the dimeric atSPT-ORM1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004758	molecular_function	serine C-palmitoyltransferase activity
A	0005515	molecular_function	protein binding
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006629	biological_process	lipid metabolic process
A	0006665	biological_process	sphingolipid metabolic process
A	0009058	biological_process	biosynthetic process
A	0009507	cellular_component	chloroplast
A	0009793	biological_process	embryo development ending in seed dormancy
A	0009825	biological_process	multidimensional cell growth
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0030148	biological_process	sphingolipid biosynthetic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0043067	biological_process	regulation of programmed cell death
A	0046512	biological_process	sphingosine biosynthetic process
A	0046513	biological_process	ceramide biosynthetic process
B	0004758	molecular_function	serine C-palmitoyltransferase activity
B	0005773	cellular_component	vacuole
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006629	biological_process	lipid metabolic process
B	0006665	biological_process	sphingolipid metabolic process
B	0009058	biological_process	biosynthetic process
B	0009507	cellular_component	chloroplast
B	0009555	biological_process	pollen development
B	0009640	biological_process	photomorphogenesis
B	0016020	cellular_component	membrane
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0017059	cellular_component	serine palmitoyltransferase complex
B	0030170	molecular_function	pyridoxal phosphate binding
B	0043067	biological_process	regulation of programmed cell death
B	0046512	biological_process	sphingosine biosynthetic process
B	0046513	biological_process	ceramide biosynthetic process
C	0005739	cellular_component	mitochondrion
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0009555	biological_process	pollen development
C	0044877	molecular_function	protein-containing complex binding
C	0090153	biological_process	regulation of sphingolipid biosynthetic process
D	0005515	molecular_function	protein binding
D	0005739	cellular_component	mitochondrion
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0006672	biological_process	ceramide metabolic process
D	0006979	biological_process	response to oxidative stress
D	0010150	biological_process	leaf senescence
D	0016020	cellular_component	membrane
D	0017059	cellular_component	serine palmitoyltransferase complex
D	0030148	biological_process	sphingolipid biosynthetic process
D	0034976	biological_process	response to endoplasmic reticulum stress
D	0042742	biological_process	defense response to bacterium
D	0090156	biological_process	intracellular sphingolipid homeostasis
E	0004758	molecular_function	serine C-palmitoyltransferase activity
E	0005515	molecular_function	protein binding
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0006629	biological_process	lipid metabolic process
E	0006665	biological_process	sphingolipid metabolic process
E	0009058	biological_process	biosynthetic process
E	0009507	cellular_component	chloroplast
E	0009793	biological_process	embryo development ending in seed dormancy
E	0009825	biological_process	multidimensional cell growth
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0030148	biological_process	sphingolipid biosynthetic process
E	0030170	molecular_function	pyridoxal phosphate binding
E	0043067	biological_process	regulation of programmed cell death
E	0046512	biological_process	sphingosine biosynthetic process
E	0046513	biological_process	ceramide biosynthetic process
F	0004758	molecular_function	serine C-palmitoyltransferase activity
F	0005773	cellular_component	vacuole
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0006629	biological_process	lipid metabolic process
F	0006665	biological_process	sphingolipid metabolic process
F	0009058	biological_process	biosynthetic process
F	0009507	cellular_component	chloroplast
F	0009555	biological_process	pollen development
F	0009640	biological_process	photomorphogenesis
F	0016020	cellular_component	membrane
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0017059	cellular_component	serine palmitoyltransferase complex
F	0030170	molecular_function	pyridoxal phosphate binding
F	0043067	biological_process	regulation of programmed cell death
F	0046512	biological_process	sphingosine biosynthetic process
F	0046513	biological_process	ceramide biosynthetic process
G	0005739	cellular_component	mitochondrion
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0009555	biological_process	pollen development
G	0044877	molecular_function	protein-containing complex binding
G	0090153	biological_process	regulation of sphingolipid biosynthetic process
H	0005515	molecular_function	protein binding
H	0005739	cellular_component	mitochondrion
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0006672	biological_process	ceramide metabolic process
H	0006979	biological_process	response to oxidative stress
H	0010150	biological_process	leaf senescence
H	0016020	cellular_component	membrane
H	0017059	cellular_component	serine palmitoyltransferase complex
H	0030148	biological_process	sphingolipid biosynthetic process
H	0034976	biological_process	response to endoplasmic reticulum stress
H	0042742	biological_process	defense response to bacterium
H	0090156	biological_process	intracellular sphingolipid homeostasis

Functional Information from PROSITE/UniProt

site_id	PS00599
Number of Residues	10
Details	AA_TRANSFER_CLASS_2 Aminotransferases class-II pyridoxal-phosphate attachment site. TFTKSFGSCG

Chain	Residue	Details
B	THR308-GLY317

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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