Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7Y8R

The nucleosome-bound human PBAF complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0006325	biological_process	chromatin organization
A	0006334	biological_process	nucleosome assembly
A	0010467	biological_process	gene expression
A	0016020	cellular_component	membrane
A	0030527	molecular_function	structural constituent of chromatin
A	0032200	biological_process	telomere organization
A	0032991	cellular_component	protein-containing complex
A	0040029	biological_process	epigenetic regulation of gene expression
A	0045296	molecular_function	cadherin binding
A	0046982	molecular_function	protein heterodimerization activity
A	0070062	cellular_component	extracellular exosome
B	0000781	cellular_component	chromosome, telomeric region
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005694	cellular_component	chromosome
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0016020	cellular_component	membrane
B	0030527	molecular_function	structural constituent of chromatin
B	0032200	biological_process	telomere organization
B	0032991	cellular_component	protein-containing complex
B	0043505	cellular_component	CENP-A containing nucleosome
B	0045653	biological_process	negative regulation of megakaryocyte differentiation
B	0046982	molecular_function	protein heterodimerization activity
B	0061644	biological_process	protein localization to CENP-A containing chromatin
B	0070062	cellular_component	extracellular exosome
C	0000786	cellular_component	nucleosome
C	0003674	molecular_function	molecular_function
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005694	cellular_component	chromosome
C	0008285	biological_process	negative regulation of cell population proliferation
C	0030527	molecular_function	structural constituent of chromatin
C	0031492	molecular_function	nucleosomal DNA binding
C	0031507	biological_process	heterochromatin formation
C	0046982	molecular_function	protein heterodimerization activity
C	0070062	cellular_component	extracellular exosome
D	0000786	cellular_component	nucleosome
D	0002227	biological_process	innate immune response in mucosa
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005615	cellular_component	extracellular space
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005694	cellular_component	chromosome
D	0005829	cellular_component	cytosol
D	0006334	biological_process	nucleosome assembly
D	0019731	biological_process	antibacterial humoral response
D	0030527	molecular_function	structural constituent of chromatin
D	0042742	biological_process	defense response to bacterium
D	0042802	molecular_function	identical protein binding
D	0046982	molecular_function	protein heterodimerization activity
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
D	0070062	cellular_component	extracellular exosome
E	0000786	cellular_component	nucleosome
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0006325	biological_process	chromatin organization
E	0006334	biological_process	nucleosome assembly
E	0010467	biological_process	gene expression
E	0016020	cellular_component	membrane
E	0030527	molecular_function	structural constituent of chromatin
E	0032200	biological_process	telomere organization
E	0032991	cellular_component	protein-containing complex
E	0040029	biological_process	epigenetic regulation of gene expression
E	0045296	molecular_function	cadherin binding
E	0046982	molecular_function	protein heterodimerization activity
E	0070062	cellular_component	extracellular exosome
F	0000781	cellular_component	chromosome, telomeric region
F	0000786	cellular_component	nucleosome
F	0003677	molecular_function	DNA binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005694	cellular_component	chromosome
F	0006325	biological_process	chromatin organization
F	0006334	biological_process	nucleosome assembly
F	0016020	cellular_component	membrane
F	0030527	molecular_function	structural constituent of chromatin
F	0032200	biological_process	telomere organization
F	0032991	cellular_component	protein-containing complex
F	0043505	cellular_component	CENP-A containing nucleosome
F	0045653	biological_process	negative regulation of megakaryocyte differentiation
F	0046982	molecular_function	protein heterodimerization activity
F	0061644	biological_process	protein localization to CENP-A containing chromatin
F	0070062	cellular_component	extracellular exosome
G	0000786	cellular_component	nucleosome
G	0003674	molecular_function	molecular_function
G	0003677	molecular_function	DNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005694	cellular_component	chromosome
G	0008285	biological_process	negative regulation of cell population proliferation
G	0030527	molecular_function	structural constituent of chromatin
G	0031492	molecular_function	nucleosomal DNA binding
G	0031507	biological_process	heterochromatin formation
G	0046982	molecular_function	protein heterodimerization activity
G	0070062	cellular_component	extracellular exosome
H	0000786	cellular_component	nucleosome
H	0002227	biological_process	innate immune response in mucosa
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005615	cellular_component	extracellular space
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005694	cellular_component	chromosome
H	0005829	cellular_component	cytosol
H	0006334	biological_process	nucleosome assembly
H	0019731	biological_process	antibacterial humoral response
H	0030527	molecular_function	structural constituent of chromatin
H	0042742	biological_process	defense response to bacterium
H	0042802	molecular_function	identical protein binding
H	0046982	molecular_function	protein heterodimerization activity
H	0050830	biological_process	defense response to Gram-positive bacterium
H	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
H	0070062	cellular_component	extracellular exosome
I	0000122	biological_process	negative regulation of transcription by RNA polymerase II
I	0000776	cellular_component	kinetochore
I	0000785	cellular_component	chromatin
I	0001164	molecular_function	RNA polymerase I core promoter sequence-specific DNA binding
I	0001188	biological_process	RNA polymerase I preinitiation complex assembly
I	0001221	molecular_function	transcription coregulator binding
I	0001650	cellular_component	fibrillar center
I	0002039	molecular_function	p53 binding
I	0003407	biological_process	neural retina development
I	0003677	molecular_function	DNA binding
I	0003713	molecular_function	transcription coactivator activity
I	0003714	molecular_function	transcription corepressor activity
I	0003723	molecular_function	RNA binding
I	0004386	molecular_function	helicase activity
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005615	cellular_component	extracellular space
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005730	cellular_component	nucleolus
I	0006325	biological_process	chromatin organization
I	0006337	biological_process	nucleosome disassembly
I	0006338	biological_process	chromatin remodeling
I	0006355	biological_process	regulation of DNA-templated transcription
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0007399	biological_process	nervous system development
I	0008094	molecular_function	ATP-dependent activity, acting on DNA
I	0008284	biological_process	positive regulation of cell population proliferation
I	0016020	cellular_component	membrane
I	0016363	cellular_component	nuclear matrix
I	0016514	cellular_component	SWI/SNF complex
I	0016586	cellular_component	RSC-type complex
I	0016787	molecular_function	hydrolase activity
I	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
I	0030177	biological_process	positive regulation of Wnt signaling pathway
I	0030308	biological_process	negative regulation of cell growth
I	0030957	molecular_function	Tat protein binding
I	0031492	molecular_function	nucleosomal DNA binding
I	0032991	cellular_component	protein-containing complex
I	0042393	molecular_function	histone binding
I	0043923	biological_process	positive regulation by host of viral transcription
I	0045582	biological_process	positive regulation of T cell differentiation
I	0045596	biological_process	negative regulation of cell differentiation
I	0045597	biological_process	positive regulation of cell differentiation
I	0045663	biological_process	positive regulation of myoblast differentiation
I	0045815	biological_process	transcription initiation-coupled chromatin remodeling
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0045893	biological_process	positive regulation of DNA-templated transcription
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0050681	molecular_function	nuclear androgen receptor binding
I	0051091	biological_process	positive regulation of DNA-binding transcription factor activity
I	0060766	biological_process	negative regulation of androgen receptor signaling pathway
I	0070182	molecular_function	DNA polymerase binding
I	0070316	biological_process	regulation of G0 to G1 transition
I	0071564	cellular_component	npBAF complex
I	0071565	cellular_component	nBAF complex
I	0120162	biological_process	positive regulation of cold-induced thermogenesis
I	0140092	cellular_component	bBAF complex
I	0140288	cellular_component	GBAF complex
I	0140658	molecular_function	ATP-dependent chromatin remodeler activity
I	1901838	biological_process	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
I	1902459	biological_process	positive regulation of stem cell population maintenance
I	1902661	biological_process	positive regulation of glucose mediated signaling pathway
I	1902895	biological_process	positive regulation of miRNA transcription
I	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
I	2000781	biological_process	positive regulation of double-strand break repair
I	2000819	biological_process	regulation of nucleotide-excision repair
J	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
J	0000776	cellular_component	kinetochore
J	0000785	cellular_component	chromatin
J	0000786	cellular_component	nucleosome
J	0001738	biological_process	morphogenesis of a polarized epithelium
J	0005200	molecular_function	structural constituent of cytoskeleton
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005615	cellular_component	extracellular space
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0005884	cellular_component	actin filament
J	0005886	cellular_component	plasma membrane
J	0005903	cellular_component	brush border
J	0005911	cellular_component	cell-cell junction
J	0005912	cellular_component	adherens junction
J	0005925	cellular_component	focal adhesion
J	0006338	biological_process	chromatin remodeling
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0007010	biological_process	cytoskeleton organization
J	0007163	biological_process	establishment or maintenance of cell polarity
J	0007409	biological_process	axonogenesis
J	0008284	biological_process	positive regulation of cell population proliferation
J	0015629	cellular_component	actin cytoskeleton
J	0016020	cellular_component	membrane
J	0016363	cellular_component	nuclear matrix
J	0016514	cellular_component	SWI/SNF complex
J	0016586	cellular_component	RSC-type complex
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019894	molecular_function	kinesin binding
J	0019901	molecular_function	protein kinase binding
J	0021762	biological_process	substantia nigra development
J	0022898	biological_process	regulation of transmembrane transporter activity
J	0030027	cellular_component	lamellipodium
J	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
J	0030424	cellular_component	axon
J	0030863	cellular_component	cortical cytoskeleton
J	0030957	molecular_function	Tat protein binding
J	0031492	molecular_function	nucleosomal DNA binding
J	0031982	cellular_component	vesicle
J	0032091	biological_process	negative regulation of protein binding
J	0032991	cellular_component	protein-containing complex
J	0034333	biological_process	adherens junction assembly
J	0035060	cellular_component	brahma complex
J	0035267	cellular_component	NuA4 histone acetyltransferase complex
J	0035633	biological_process	maintenance of blood-brain barrier
J	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
J	0042802	molecular_function	identical protein binding
J	0042981	biological_process	regulation of apoptotic process
J	0043296	cellular_component	apical junction complex
J	0044305	cellular_component	calyx of Held
J	0045176	biological_process	apical protein localization
J	0045202	cellular_component	synapse
J	0045582	biological_process	positive regulation of T cell differentiation
J	0045596	biological_process	negative regulation of cell differentiation
J	0045597	biological_process	positive regulation of cell differentiation
J	0045663	biological_process	positive regulation of myoblast differentiation
J	0045893	biological_process	positive regulation of DNA-templated transcription
J	0048156	molecular_function	tau protein binding
J	0048870	biological_process	cell motility
J	0050998	molecular_function	nitric-oxide synthase binding
J	0051621	biological_process	regulation of norepinephrine uptake
J	0051623	biological_process	positive regulation of norepinephrine uptake
J	0051726	biological_process	regulation of cell cycle
J	0070062	cellular_component	extracellular exosome
J	0070160	cellular_component	tight junction
J	0070316	biological_process	regulation of G0 to G1 transition
J	0070527	biological_process	platelet aggregation
J	0071564	cellular_component	npBAF complex
J	0071565	cellular_component	nBAF complex
J	0071896	biological_process	protein localization to adherens junction
J	0072562	cellular_component	blood microparticle
J	0072749	biological_process	cellular response to cytochalasin B
J	0097433	cellular_component	dense body
J	0098685	cellular_component	Schaffer collateral - CA1 synapse
J	0098793	cellular_component	presynapse
J	0098871	cellular_component	postsynaptic actin cytoskeleton
J	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
J	0098974	biological_process	postsynaptic actin cytoskeleton organization
J	0098978	cellular_component	glutamatergic synapse
J	0140092	cellular_component	bBAF complex
J	0140288	cellular_component	GBAF complex
J	0150111	biological_process	regulation of transepithelial transport
J	1900242	biological_process	regulation of synaptic vesicle endocytosis
J	1902459	biological_process	positive regulation of stem cell population maintenance
J	1903076	biological_process	regulation of protein localization to plasma membrane
J	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
J	1990904	cellular_component	ribonucleoprotein complex
J	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
J	2000779	biological_process	regulation of double-strand break repair
J	2000781	biological_process	positive regulation of double-strand break repair
J	2000819	biological_process	regulation of nucleotide-excision repair
K	0000723	biological_process	telomere maintenance
K	0000776	cellular_component	kinetochore
K	0000785	cellular_component	chromatin
K	0000786	cellular_component	nucleosome
K	0001825	biological_process	blastocyst formation
K	0003407	biological_process	neural retina development
K	0003682	molecular_function	chromatin binding
K	0003713	molecular_function	transcription coactivator activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005886	cellular_component	plasma membrane
K	0006275	biological_process	regulation of DNA replication
K	0006281	biological_process	DNA repair
K	0006282	biological_process	regulation of DNA repair
K	0006310	biological_process	DNA recombination
K	0006325	biological_process	chromatin organization
K	0006338	biological_process	chromatin remodeling
K	0006355	biological_process	regulation of DNA-templated transcription
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0007165	biological_process	signal transduction
K	0007399	biological_process	nervous system development
K	0008284	biological_process	positive regulation of cell population proliferation
K	0016363	cellular_component	nuclear matrix
K	0016514	cellular_component	SWI/SNF complex
K	0016586	cellular_component	RSC-type complex
K	0021510	biological_process	spinal cord development
K	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
K	0031011	cellular_component	Ino80 complex
K	0031492	molecular_function	nucleosomal DNA binding
K	0032991	cellular_component	protein-containing complex
K	0033044	biological_process	regulation of chromosome organization
K	0035060	cellular_component	brahma complex
K	0035267	cellular_component	NuA4 histone acetyltransferase complex
K	0042981	biological_process	regulation of apoptotic process
K	0045582	biological_process	positive regulation of T cell differentiation
K	0045596	biological_process	negative regulation of cell differentiation
K	0045597	biological_process	positive regulation of cell differentiation
K	0045663	biological_process	positive regulation of myoblast differentiation
K	0045739	biological_process	positive regulation of DNA repair
K	0045893	biological_process	positive regulation of DNA-templated transcription
K	0045995	biological_process	regulation of embryonic development
K	0051726	biological_process	regulation of cell cycle
K	0060382	biological_process	regulation of DNA strand elongation
K	0070316	biological_process	regulation of G0 to G1 transition
K	0071564	cellular_component	npBAF complex
K	0140288	cellular_component	GBAF complex
K	1902459	biological_process	positive regulation of stem cell population maintenance
K	1904507	biological_process	positive regulation of telomere maintenance in response to DNA damage
K	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
K	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
K	2000779	biological_process	regulation of double-strand break repair
K	2000781	biological_process	positive regulation of double-strand break repair
K	2000819	biological_process	regulation of nucleotide-excision repair
L	0000776	cellular_component	kinetochore
L	0000785	cellular_component	chromatin
L	0003007	biological_process	heart morphogenesis
L	0003677	molecular_function	DNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005886	cellular_component	plasma membrane
L	0006325	biological_process	chromatin organization
L	0006337	biological_process	nucleosome disassembly
L	0006338	biological_process	chromatin remodeling
L	0006355	biological_process	regulation of DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0008285	biological_process	negative regulation of cell population proliferation
L	0016363	cellular_component	nuclear matrix
L	0016514	cellular_component	SWI/SNF complex
L	0016586	cellular_component	RSC-type complex
L	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
L	0030336	biological_process	negative regulation of cell migration
L	0042592	biological_process	homeostatic process
L	0045582	biological_process	positive regulation of T cell differentiation
L	0045597	biological_process	positive regulation of cell differentiation
L	0045663	biological_process	positive regulation of myoblast differentiation
L	0046872	molecular_function	metal ion binding
L	0048568	biological_process	embryonic organ development
L	0060038	biological_process	cardiac muscle cell proliferation
L	0060982	biological_process	coronary artery morphogenesis
L	0070316	biological_process	regulation of G0 to G1 transition
L	0072359	biological_process	circulatory system development
L	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
L	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
L	2000781	biological_process	positive regulation of double-strand break repair
L	2000819	biological_process	regulation of nucleotide-excision repair
M	0000228	cellular_component	nuclear chromosome
M	0000776	cellular_component	kinetochore
M	0000785	cellular_component	chromatin
M	0001164	molecular_function	RNA polymerase I core promoter sequence-specific DNA binding
M	0001188	biological_process	RNA polymerase I preinitiation complex assembly
M	0001650	cellular_component	fibrillar center
M	0001741	cellular_component	XY body
M	0001824	biological_process	blastocyst development
M	0001835	biological_process	blastocyst hatching
M	0002039	molecular_function	p53 binding
M	0003677	molecular_function	DNA binding
M	0003713	molecular_function	transcription coactivator activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005730	cellular_component	nucleolus
M	0006325	biological_process	chromatin organization
M	0006337	biological_process	nucleosome disassembly
M	0006338	biological_process	chromatin remodeling
M	0006357	biological_process	regulation of transcription by RNA polymerase II
M	0007399	biological_process	nervous system development
M	0008285	biological_process	negative regulation of cell population proliferation
M	0015074	biological_process	DNA integration
M	0016363	cellular_component	nuclear matrix
M	0016514	cellular_component	SWI/SNF complex
M	0016586	cellular_component	RSC-type complex
M	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
M	0030957	molecular_function	Tat protein binding
M	0031492	molecular_function	nucleosomal DNA binding
M	0032991	cellular_component	protein-containing complex
M	0035060	cellular_component	brahma complex
M	0039692	biological_process	single stranded viral RNA replication via double stranded DNA intermediate
M	0042802	molecular_function	identical protein binding
M	0043073	cellular_component	germ cell nucleus
M	0043231	cellular_component	intracellular membrane-bounded organelle
M	0043923	biological_process	positive regulation by host of viral transcription
M	0045582	biological_process	positive regulation of T cell differentiation
M	0045597	biological_process	positive regulation of cell differentiation
M	0045663	biological_process	positive regulation of myoblast differentiation
M	0045815	biological_process	transcription initiation-coupled chromatin remodeling
M	0045944	biological_process	positive regulation of transcription by RNA polymerase II
M	0051091	biological_process	positive regulation of DNA-binding transcription factor activity
M	0070316	biological_process	regulation of G0 to G1 transition
M	0070365	biological_process	hepatocyte differentiation
M	0071564	cellular_component	npBAF complex
M	0071565	cellular_component	nBAF complex
M	0140092	cellular_component	bBAF complex
M	1901838	biological_process	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
M	1902459	biological_process	positive regulation of stem cell population maintenance
M	1902661	biological_process	positive regulation of glucose mediated signaling pathway
M	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
M	2000781	biological_process	positive regulation of double-strand break repair
M	2000819	biological_process	regulation of nucleotide-excision repair
N	0000776	cellular_component	kinetochore
N	0000785	cellular_component	chromatin
N	0003713	molecular_function	transcription coactivator activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005694	cellular_component	chromosome
N	0006325	biological_process	chromatin organization
N	0006337	biological_process	nucleosome disassembly
N	0006338	biological_process	chromatin remodeling
N	0006357	biological_process	regulation of transcription by RNA polymerase II
N	0007399	biological_process	nervous system development
N	0016363	cellular_component	nuclear matrix
N	0016514	cellular_component	SWI/SNF complex
N	0016586	cellular_component	RSC-type complex
N	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
N	0031492	molecular_function	nucleosomal DNA binding
N	0032991	cellular_component	protein-containing complex
N	0035060	cellular_component	brahma complex
N	0042393	molecular_function	histone binding
N	0045582	biological_process	positive regulation of T cell differentiation
N	0045597	biological_process	positive regulation of cell differentiation
N	0045663	biological_process	positive regulation of myoblast differentiation
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0045893	biological_process	positive regulation of DNA-templated transcription
N	0070316	biological_process	regulation of G0 to G1 transition
N	0071564	cellular_component	npBAF complex
N	0071565	cellular_component	nBAF complex
N	0140092	cellular_component	bBAF complex
N	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
N	2000781	biological_process	positive regulation of double-strand break repair
N	2000819	biological_process	regulation of nucleotide-excision repair
O	0000776	cellular_component	kinetochore
O	0000785	cellular_component	chromatin
O	0003713	molecular_function	transcription coactivator activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005694	cellular_component	chromosome
O	0006325	biological_process	chromatin organization
O	0006337	biological_process	nucleosome disassembly
O	0006338	biological_process	chromatin remodeling
O	0006357	biological_process	regulation of transcription by RNA polymerase II
O	0007399	biological_process	nervous system development
O	0016363	cellular_component	nuclear matrix
O	0016514	cellular_component	SWI/SNF complex
O	0016586	cellular_component	RSC-type complex
O	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
O	0031492	molecular_function	nucleosomal DNA binding
O	0032991	cellular_component	protein-containing complex
O	0035060	cellular_component	brahma complex
O	0042393	molecular_function	histone binding
O	0045582	biological_process	positive regulation of T cell differentiation
O	0045597	biological_process	positive regulation of cell differentiation
O	0045663	biological_process	positive regulation of myoblast differentiation
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0045893	biological_process	positive regulation of DNA-templated transcription
O	0070316	biological_process	regulation of G0 to G1 transition
O	0071564	cellular_component	npBAF complex
O	0071565	cellular_component	nBAF complex
O	0140092	cellular_component	bBAF complex
O	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
O	2000781	biological_process	positive regulation of double-strand break repair
O	2000819	biological_process	regulation of nucleotide-excision repair
P	0000776	cellular_component	kinetochore
P	0000785	cellular_component	chromatin
P	0003682	molecular_function	chromatin binding
P	0003712	molecular_function	transcription coregulator activity
P	0003713	molecular_function	transcription coactivator activity
P	0005102	molecular_function	signaling receptor binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0006325	biological_process	chromatin organization
P	0006337	biological_process	nucleosome disassembly
P	0006338	biological_process	chromatin remodeling
P	0006357	biological_process	regulation of transcription by RNA polymerase II
P	0007399	biological_process	nervous system development
P	0008284	biological_process	positive regulation of cell population proliferation
P	0016363	cellular_component	nuclear matrix
P	0016514	cellular_component	SWI/SNF complex
P	0016586	cellular_component	RSC-type complex
P	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
P	0035060	cellular_component	brahma complex
P	0043231	cellular_component	intracellular membrane-bounded organelle
P	0045582	biological_process	positive regulation of T cell differentiation
P	0045596	biological_process	negative regulation of cell differentiation
P	0045597	biological_process	positive regulation of cell differentiation
P	0045663	biological_process	positive regulation of myoblast differentiation
P	0045815	biological_process	transcription initiation-coupled chromatin remodeling
P	0045893	biological_process	positive regulation of DNA-templated transcription
P	0060090	molecular_function	molecular adaptor activity
P	0070316	biological_process	regulation of G0 to G1 transition
P	0071398	biological_process	cellular response to fatty acid
P	0071564	cellular_component	npBAF complex
P	0071565	cellular_component	nBAF complex
P	0140288	cellular_component	GBAF complex
P	1902459	biological_process	positive regulation of stem cell population maintenance
P	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
P	2000781	biological_process	positive regulation of double-strand break repair
P	2000819	biological_process	regulation of nucleotide-excision repair
Q	0000228	cellular_component	nuclear chromosome
Q	0000776	cellular_component	kinetochore
Q	0000785	cellular_component	chromatin
Q	0003677	molecular_function	DNA binding
Q	0003682	molecular_function	chromatin binding
Q	0003713	molecular_function	transcription coactivator activity
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0006325	biological_process	chromatin organization
Q	0006337	biological_process	nucleosome disassembly
Q	0006338	biological_process	chromatin remodeling
Q	0006357	biological_process	regulation of transcription by RNA polymerase II
Q	0007399	biological_process	nervous system development
Q	0008080	molecular_function	N-acetyltransferase activity
Q	0016363	cellular_component	nuclear matrix
Q	0016514	cellular_component	SWI/SNF complex
Q	0016586	cellular_component	RSC-type complex
Q	0016922	molecular_function	nuclear receptor binding
Q	0022008	biological_process	neurogenesis
Q	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
Q	0031492	molecular_function	nucleosomal DNA binding
Q	0032991	cellular_component	protein-containing complex
Q	0035060	cellular_component	brahma complex
Q	0045582	biological_process	positive regulation of T cell differentiation
Q	0045597	biological_process	positive regulation of cell differentiation
Q	0045663	biological_process	positive regulation of myoblast differentiation
Q	0045892	biological_process	negative regulation of DNA-templated transcription
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0070316	biological_process	regulation of G0 to G1 transition
Q	0071564	cellular_component	npBAF complex
Q	0071565	cellular_component	nBAF complex
Q	0140092	cellular_component	bBAF complex
Q	1902459	biological_process	positive regulation of stem cell population maintenance
Q	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
Q	2000781	biological_process	positive regulation of double-strand break repair
Q	2000819	biological_process	regulation of nucleotide-excision repair
R	0000776	cellular_component	kinetochore
R	0000785	cellular_component	chromatin
R	0003682	molecular_function	chromatin binding
R	0003712	molecular_function	transcription coregulator activity
R	0004402	molecular_function	histone acetyltransferase activity
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0006338	biological_process	chromatin remodeling
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0007399	biological_process	nervous system development
R	0016363	cellular_component	nuclear matrix
R	0016514	cellular_component	SWI/SNF complex
R	0016586	cellular_component	RSC-type complex
R	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
R	0045582	biological_process	positive regulation of T cell differentiation
R	0045597	biological_process	positive regulation of cell differentiation
R	0045663	biological_process	positive regulation of myoblast differentiation
R	0046872	molecular_function	metal ion binding
R	0070316	biological_process	regulation of G0 to G1 transition
R	0071564	cellular_component	npBAF complex
R	1902459	biological_process	positive regulation of stem cell population maintenance
R	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
R	2000781	biological_process	positive regulation of double-strand break repair
R	2000819	biological_process	regulation of nucleotide-excision repair
S	0000776	cellular_component	kinetochore
S	0000785	cellular_component	chromatin
S	0000976	molecular_function	transcription cis-regulatory region binding
S	0002039	molecular_function	p53 binding
S	0003713	molecular_function	transcription coactivator activity
S	0003714	molecular_function	transcription corepressor activity
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005694	cellular_component	chromosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006338	biological_process	chromatin remodeling
S	0006357	biological_process	regulation of transcription by RNA polymerase II
S	0007346	biological_process	regulation of mitotic cell cycle
S	0016055	biological_process	Wnt signaling pathway
S	0016363	cellular_component	nuclear matrix
S	0016586	cellular_component	RSC-type complex
S	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
S	0042393	molecular_function	histone binding
S	0045582	biological_process	positive regulation of T cell differentiation
S	0045597	biological_process	positive regulation of cell differentiation
S	0045663	biological_process	positive regulation of myoblast differentiation
S	0045815	biological_process	transcription initiation-coupled chromatin remodeling
S	0045892	biological_process	negative regulation of DNA-templated transcription
S	0045893	biological_process	positive regulation of DNA-templated transcription
S	0070316	biological_process	regulation of G0 to G1 transition
S	0070577	molecular_function	lysine-acetylated histone binding
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	2000134	biological_process	negative regulation of G1/S transition of mitotic cell cycle
S	2000781	biological_process	positive regulation of double-strand break repair
S	2000819	biological_process	regulation of nucleotide-excision repair
U	0003682	molecular_function	chromatin binding
U	0006338	biological_process	chromatin remodeling
U	0016586	cellular_component	RSC-type complex

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	24
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. ClwqsCkkwFqtpsqvfyHaate.H

Chain	Residue	Details
L	CYS1634-HIS1657

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
C	ALA21-VAL27

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY14-HIS18

site_id	PS00063
Number of Residues	16
Details	ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. MAKSSLrmRTpSNlAA

Chain	Residue	Details
U	MET292-ALA307

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LILDSGATHTTA

Chain	Residue	Details
K	LEU168-ALA179

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
A	LYS14-LEU20

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
D	ARG92-GLY114

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
J	TYR53-GLY63

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
J	TRP356-GLU364
K	TRP410-GLU418

site_id	PS00633
Number of Residues	55
Details	BROMODOMAIN_1 Bromodomain signature. FirApkrrNqp.....DYYevVsqpIdlmkIqqklkmee..Yddvnlltadfql.LfnNAksY

Chain	Residue	Details
U	PHE72-TYR126
U	SER205-TYR262
U	ALA405-TYR462
U	VAL563-TYR615
U	SER696-TYR753
I	SER1482-PHE1539

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
A	PRO66-ILE74

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
J	LEU104-ARG116

site_id	PS01359
Number of Residues	78
Details	ZF_PHD_1 Zinc finger PHD-type signature. CsqCensghpscldmtmelvsmiktypwqcmecktciicgqphheeem.MfCdm..Cdrg.YHtfCvglgaipsgr...................................WiCdcC

Chain	Residue	Details
R	CYS401-CYS478

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	DNA_BIND:

Chain	Residue	Details
B	LYS16-LYS20
F	LYS16-LYS20

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269\|PubMed:17967882

Chain	Residue	Details
B	SER1
F	SER1
M	LYS108
M	LYS124
M	LYS161

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate => ECO:0000250\|UniProtKB:P62806

Chain	Residue	Details
B	ARG3
H	LYS11
H	LYS15
H	LYS16
H	LYS20
H	LYS23
H	LYS43
H	LYS85
F	ARG3
D	LYS15
D	LYS16
D	LYS20
D	LYS23
D	LYS43
D	LYS85
H	LYS5

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-lactoyllysine; alternate => ECO:0000269\|PubMed:31645732

Chain	Residue	Details
B	LYS5
F	LYS5
U	SER319
Q	LYS166
Q	LYS277

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: N6-propionyllysine; alternate => ECO:0000269\|PubMed:17267393

Chain	Residue	Details
B	LYS8
B	LYS16
B	LYS44
F	LYS8
F	LYS16
F	LYS44

site_id	SWS_FT_FI6
Number of Residues	8
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269\|PubMed:22389435

Chain	Residue	Details
B	LYS12
B	LYS31
B	LYS77
B	LYS91
F	LYS12
F	LYS31
F	LYS77
F	LYS91

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269\|PubMed:12086618, ECO:0000269\|PubMed:15964846, ECO:0000269\|PubMed:17967882, ECO:0000269\|PubMed:27338793

Chain	Residue	Details
B	LYS20
F	LYS20
S	LYS305
G	LYS75

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphoserine; by PAK2 => ECO:0000269\|PubMed:21724829, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
B	SER47
S	LYS389
F	SER47
D	LYS120
H	LYS34
H	LYS116
H	LYS120
S	LYS241
S	LYS307
S	LYS344

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744\|PubMed:15592455, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
B	TYR51
F	TYR51
L	LYS15
L	LYS119
L	LYS555
L	LYS1701
L	LYS1716
L	LYS1731

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000269\|PubMed:31542297

Chain	Residue	Details
B	LYS59
F	LYS59
E	LYS14
E	LYS56

site_id	SWS_FT_FI11
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250\|UniProtKB:P62806

Chain	Residue	Details
B	LYS79
F	LYS79
H	LYS46
H	LYS108

site_id	SWS_FT_FI12
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P62806

Chain	Residue	Details
B	THR80
F	THR80
E	LYS18
E	LYS64
O	LYS564
O	LYS568
O	LYS592
O	LYS787

site_id	SWS_FT_FI13
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
B	TYR88
F	TYR88
O	LYS848

site_id	SWS_FT_FI14
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25218447

Chain	Residue	Details
B	LYS12
F	LYS12
H	ARG86
H	ARG92

site_id	SWS_FT_FI15
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269\|PubMed:19818714

Chain	Residue	Details
A	LYS27
B	LYS91
F	LYS91

site_id	SWS_FT_FI16
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
B	LYS20
B	LYS59
B	LYS79
F	LYS20
F	LYS59
F	LYS79

site_id	SWS_FT_FI17
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000269\|PubMed:30886146

Chain	Residue	Details
B	LYS31
U	LYS1121
U	LYS1126
U	LYS1182
F	LYS31
U	LYS154
U	LYS210
U	LYS425
U	LYS471
U	LYS511
U	LYS606
U	LYS653

site_id	SWS_FT_FI18
Number of Residues	2
Details	MOD_RES: N6-methyllysine => ECO:0000269\|PubMed:15983376

Chain	Residue	Details
A	LYS37
E	LYS37
U	LYS1413
H	LYS120

site_id	SWS_FT_FI19
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000269\|PubMed:19783980

Chain	Residue	Details
A	TYR41
E	TYR41

site_id	SWS_FT_FI20
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269\|PubMed:20850016

Chain	Residue	Details
A	SER57
E	SER57

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269\|PubMed:22389435, ECO:0000269\|PubMed:29211711

Chain	Residue	Details
A	LYS79
E	LYS79

site_id	SWS_FT_FI22
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000269\|PubMed:20850016

Chain	Residue	Details
A	THR80
E	THR80

site_id	SWS_FT_FI23
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P84243

Chain	Residue	Details
A	SER86
E	SER86

site_id	SWS_FT_FI24
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:Q71DI3

Chain	Residue	Details
A	THR107
E	THR107

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000269\|PubMed:31542297

Chain	Residue	Details
A	LYS115
E	LYS115

site_id	SWS_FT_FI26
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269\|PubMed:22389435, ECO:0000269\|PubMed:27436229

Chain	Residue	Details
A	LYS122
E	LYS122

site_id	SWS_FT_FI27
Number of Residues	2
Details	LIPID: N6-decanoyllysine => ECO:0000269\|PubMed:35939806

Chain	Residue	Details
A	LYS18
E	LYS18

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)