7Y1I
Crystal Structure of TTR-G67R
Functional Information from PROSITE/UniProt
| site_id | PS00769 |
| Number of Residues | 13 |
| Details | TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS |
| Chain | Residue | Details |
| A | TYR105-SER117 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT |
| Chain | Residue | Details |
| A | LYS15 | |
| D | LYS15 | |
| D | GLU54 | |
| D | SER117 | |
| E | LYS15 | |
| E | GLU54 | |
| E | SER117 | |
| F | LYS15 | |
| F | GLU54 | |
| F | SER117 | |
| G | LYS15 | |
| A | GLU54 | |
| G | GLU54 | |
| G | SER117 | |
| H | LYS15 | |
| H | GLU54 | |
| H | SER117 | |
| I | LYS15 | |
| I | GLU54 | |
| I | SER117 | |
| J | LYS15 | |
| J | GLU54 | |
| A | SER117 | |
| J | SER117 | |
| K | LYS15 | |
| K | GLU54 | |
| K | SER117 | |
| L | LYS15 | |
| L | GLU54 | |
| L | SER117 | |
| M | LYS15 | |
| M | GLU54 | |
| M | SER117 | |
| B | LYS15 | |
| N | LYS15 | |
| N | GLU54 | |
| N | SER117 | |
| O | LYS15 | |
| O | GLU54 | |
| O | SER117 | |
| P | LYS15 | |
| P | GLU54 | |
| P | SER117 | |
| Q | LYS15 | |
| B | GLU54 | |
| Q | GLU54 | |
| Q | SER117 | |
| R | LYS15 | |
| R | GLU54 | |
| R | SER117 | |
| S | LYS15 | |
| S | GLU54 | |
| S | SER117 | |
| T | LYS15 | |
| T | GLU54 | |
| B | SER117 | |
| T | SER117 | |
| U | LYS15 | |
| U | GLU54 | |
| U | SER117 | |
| V | LYS15 | |
| V | GLU54 | |
| V | SER117 | |
| W | LYS15 | |
| W | GLU54 | |
| W | SER117 | |
| C | LYS15 | |
| X | LYS15 | |
| X | GLU54 | |
| X | SER117 | |
| C | GLU54 | |
| C | SER117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | MOD_RES: Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E |
| Chain | Residue | Details |
| A | CYS10 | |
| J | CYS10 | |
| K | CYS10 | |
| L | CYS10 | |
| M | CYS10 | |
| N | CYS10 | |
| O | CYS10 | |
| P | CYS10 | |
| Q | CYS10 | |
| R | CYS10 | |
| S | CYS10 | |
| B | CYS10 | |
| T | CYS10 | |
| U | CYS10 | |
| V | CYS10 | |
| W | CYS10 | |
| X | CYS10 | |
| C | CYS10 | |
| D | CYS10 | |
| E | CYS10 | |
| F | CYS10 | |
| G | CYS10 | |
| H | CYS10 | |
| I | CYS10 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | MOD_RES: 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 |
| Chain | Residue | Details |
| A | GLU42 | |
| J | GLU42 | |
| K | GLU42 | |
| L | GLU42 | |
| M | GLU42 | |
| N | GLU42 | |
| O | GLU42 | |
| P | GLU42 | |
| Q | GLU42 | |
| R | GLU42 | |
| S | GLU42 | |
| B | GLU42 | |
| T | GLU42 | |
| U | GLU42 | |
| V | GLU42 | |
| W | GLU42 | |
| X | GLU42 | |
| C | GLU42 | |
| D | GLU42 | |
| E | GLU42 | |
| F | GLU42 | |
| G | GLU42 | |
| H | GLU42 | |
| I | GLU42 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P02767 |
| Chain | Residue | Details |
| A | SER52 | |
| J | SER52 | |
| K | SER52 | |
| L | SER52 | |
| M | SER52 | |
| N | SER52 | |
| O | SER52 | |
| P | SER52 | |
| Q | SER52 | |
| R | SER52 | |
| S | SER52 | |
| B | SER52 | |
| T | SER52 | |
| U | SER52 | |
| V | SER52 | |
| W | SER52 | |
| X | SER52 | |
| C | SER52 | |
| D | SER52 | |
| E | SER52 | |
| F | SER52 | |
| G | SER52 | |
| H | SER52 | |
| I | SER52 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 |
| Chain | Residue | Details |
| A | ASN98 | |
| J | ASN98 | |
| K | ASN98 | |
| L | ASN98 | |
| M | ASN98 | |
| N | ASN98 | |
| O | ASN98 | |
| P | ASN98 | |
| Q | ASN98 | |
| R | ASN98 | |
| S | ASN98 | |
| B | ASN98 | |
| T | ASN98 | |
| U | ASN98 | |
| V | ASN98 | |
| W | ASN98 | |
| X | ASN98 | |
| C | ASN98 | |
| D | ASN98 | |
| E | ASN98 | |
| F | ASN98 | |
| G | ASN98 | |
| H | ASN98 | |
| I | ASN98 |
