7XO4
SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with two mouse ACE2 Bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
| A | 0019031 | cellular_component | viral envelope |
| A | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| A | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| A | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| A | 0055036 | cellular_component | virion membrane |
| A | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| C | 0016020 | cellular_component | membrane |
| C | 0019031 | cellular_component | viral envelope |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| C | 0055036 | cellular_component | virion membrane |
| C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| D | 0006508 | biological_process | proteolysis |
| D | 0008237 | molecular_function | metallopeptidase activity |
| D | 0008241 | molecular_function | peptidyl-dipeptidase activity |
| D | 0016020 | cellular_component | membrane |
| E | 0006508 | biological_process | proteolysis |
| E | 0008237 | molecular_function | metallopeptidase activity |
| E | 0008241 | molecular_function | peptidyl-dipeptidase activity |
| E | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1444 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| D | GLN18-THR740 | |
| E | GLN18-THR740 | |
| C | SER685 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical => ECO:0000255|PROSITE-ProRule:PRU01354 |
| Chain | Residue | Details |
| D | ILE741-ILE761 | |
| E | ILE741-ILE761 | |
| C | ARG815 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 86 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| D | VAL762-PHE805 | |
| E | VAL762-PHE805 | |
| A | ASN1173 | |
| B | ASN17 | |
| B | ASN1158 | |
| B | ASN1173 | |
| C | ASN17 | |
| C | ASN1158 | |
| C | ASN1173 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01355 |
| Chain | Residue | Details |
| D | GLU375 | |
| B | ASN1074 | |
| C | ASN61 | |
| C | THR124 | |
| C | ASN717 | |
| C | ASN801 | |
| C | ASN1074 | |
| E | GLU375 | |
| A | ASN717 | |
| A | ASN801 | |
| A | ASN1074 | |
| B | ASN61 | |
| B | THR124 | |
| B | ASN717 | |
| B | ASN801 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01355 |
| Chain | Residue | Details |
| D | HIS505 | |
| E | HIS505 | |
| A | ASN1194 | |
| B | THR76 | |
| B | GLU154 | |
| B | ASN1194 | |
| C | THR76 | |
| C | GLU154 | |
| C | ASN1194 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01355 |
| Chain | Residue | Details |
| D | ARG169 | |
| E | GLU402 | |
| E | TRP477 | |
| E | LYS481 | |
| B | ASN657 | |
| B | ASN1098 | |
| C | TYR170 | |
| C | ASN282 | |
| C | ASN331 | |
| C | ASN343 | |
| C | ASN616 | |
| D | HIS374 | |
| C | ASN657 | |
| C | ASN1098 | |
| D | HIS378 | |
| D | GLU402 | |
| D | TRP477 | |
| D | LYS481 | |
| E | ARG169 | |
| E | HIS374 | |
| E | HIS378 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9BYF1 |
| Chain | Residue | Details |
| D | ARG273 | |
| D | HIS345 | |
| D | TYR515 | |
| E | ARG273 | |
| E | HIS345 | |
| E | TYR515 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q9BYF1 |
| Chain | Residue | Details |
| D | TYR781 | |
| E | TYR781 | |
| C | THR323 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9BYF1 |
| Chain | Residue | Details |
| D | SER783 | |
| E | SER783 | |
| C | SER325 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 10 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN53 | |
| E | ASN690 | |
| D | ASN536 | |
| D | ASN546 | |
| D | ASN660 | |
| D | ASN690 | |
| E | ASN53 | |
| E | ASN536 | |
| E | ASN546 | |
| E | ASN660 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q9BYF1 |
| Chain | Residue | Details |
| D | LYS788 | |
| A | THR678 | |
| E | LYS788 | |
| B | THR678 | |
| C | THR676 | |
| C | THR678 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN1134 | |
| B | ASN1134 | |
| C | ASN1134 |
