7X7Q

CryoEM structure of RuvA-RuvB-Holliday junction complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000400	molecular_function	four-way junction DNA binding
A	0003677	molecular_function	DNA binding
A	0003678	molecular_function	DNA helicase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006974	biological_process	DNA damage response
A	0009378	molecular_function	four-way junction helicase activity
A	0009379	cellular_component	Holliday junction helicase complex
A	0009432	biological_process	SOS response
A	0048476	cellular_component	Holliday junction resolvase complex
B	0000400	molecular_function	four-way junction DNA binding
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006974	biological_process	DNA damage response
B	0009378	molecular_function	four-way junction helicase activity
B	0009379	cellular_component	Holliday junction helicase complex
B	0009432	biological_process	SOS response
B	0048476	cellular_component	Holliday junction resolvase complex
C	0000400	molecular_function	four-way junction DNA binding
C	0003677	molecular_function	DNA binding
C	0003678	molecular_function	DNA helicase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006974	biological_process	DNA damage response
C	0009378	molecular_function	four-way junction helicase activity
C	0009379	cellular_component	Holliday junction helicase complex
C	0009432	biological_process	SOS response
C	0048476	cellular_component	Holliday junction resolvase complex
D	0000400	molecular_function	four-way junction DNA binding
D	0003677	molecular_function	DNA binding
D	0003678	molecular_function	DNA helicase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0006974	biological_process	DNA damage response
D	0009378	molecular_function	four-way junction helicase activity
D	0009379	cellular_component	Holliday junction helicase complex
D	0009432	biological_process	SOS response
D	0048476	cellular_component	Holliday junction resolvase complex
E	0000400	molecular_function	four-way junction DNA binding
E	0003677	molecular_function	DNA binding
E	0003678	molecular_function	DNA helicase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0006974	biological_process	DNA damage response
E	0009378	molecular_function	four-way junction helicase activity
E	0009379	cellular_component	Holliday junction helicase complex
E	0009432	biological_process	SOS response
E	0048476	cellular_component	Holliday junction resolvase complex
F	0000400	molecular_function	four-way junction DNA binding
F	0003677	molecular_function	DNA binding
F	0003678	molecular_function	DNA helicase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006281	biological_process	DNA repair
F	0006310	biological_process	DNA recombination
F	0006974	biological_process	DNA damage response
F	0009378	molecular_function	four-way junction helicase activity
F	0009379	cellular_component	Holliday junction helicase complex
F	0009432	biological_process	SOS response
F	0048476	cellular_component	Holliday junction resolvase complex
G	0000400	molecular_function	four-way junction DNA binding
G	0003677	molecular_function	DNA binding
G	0003678	molecular_function	DNA helicase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006281	biological_process	DNA repair
G	0006310	biological_process	DNA recombination
G	0006974	biological_process	DNA damage response
G	0009378	molecular_function	four-way junction helicase activity
G	0009379	cellular_component	Holliday junction helicase complex
G	0009432	biological_process	SOS response
G	0048476	cellular_component	Holliday junction resolvase complex
H	0000400	molecular_function	four-way junction DNA binding
H	0003677	molecular_function	DNA binding
H	0003678	molecular_function	DNA helicase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006281	biological_process	DNA repair
H	0006310	biological_process	DNA recombination
H	0006974	biological_process	DNA damage response
H	0009378	molecular_function	four-way junction helicase activity
H	0009379	cellular_component	Holliday junction helicase complex
H	0009432	biological_process	SOS response
H	0048476	cellular_component	Holliday junction resolvase complex
M	0000166	molecular_function	nucleotide binding
M	0000400	molecular_function	four-way junction DNA binding
M	0000725	biological_process	recombinational repair
M	0003677	molecular_function	DNA binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0006281	biological_process	DNA repair
M	0006310	biological_process	DNA recombination
M	0006974	biological_process	DNA damage response
M	0009378	molecular_function	four-way junction helicase activity
M	0009379	cellular_component	Holliday junction helicase complex
M	0009432	biological_process	SOS response
M	0016787	molecular_function	hydrolase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0048476	cellular_component	Holliday junction resolvase complex
M	0071247	biological_process	cellular response to chromate
M	0072715	biological_process	cellular response to selenite ion
N	0000166	molecular_function	nucleotide binding
N	0000400	molecular_function	four-way junction DNA binding
N	0000725	biological_process	recombinational repair
N	0003677	molecular_function	DNA binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0006281	biological_process	DNA repair
N	0006310	biological_process	DNA recombination
N	0006974	biological_process	DNA damage response
N	0009378	molecular_function	four-way junction helicase activity
N	0009379	cellular_component	Holliday junction helicase complex
N	0009432	biological_process	SOS response
N	0016787	molecular_function	hydrolase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0048476	cellular_component	Holliday junction resolvase complex
N	0071247	biological_process	cellular response to chromate
N	0072715	biological_process	cellular response to selenite ion
O	0000166	molecular_function	nucleotide binding
O	0000400	molecular_function	four-way junction DNA binding
O	0000725	biological_process	recombinational repair
O	0003677	molecular_function	DNA binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0006281	biological_process	DNA repair
O	0006310	biological_process	DNA recombination
O	0006974	biological_process	DNA damage response
O	0009378	molecular_function	four-way junction helicase activity
O	0009379	cellular_component	Holliday junction helicase complex
O	0009432	biological_process	SOS response
O	0016787	molecular_function	hydrolase activity
O	0016887	molecular_function	ATP hydrolysis activity
O	0048476	cellular_component	Holliday junction resolvase complex
O	0071247	biological_process	cellular response to chromate
O	0072715	biological_process	cellular response to selenite ion
P	0000166	molecular_function	nucleotide binding
P	0000400	molecular_function	four-way junction DNA binding
P	0000725	biological_process	recombinational repair
P	0003677	molecular_function	DNA binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0006281	biological_process	DNA repair
P	0006310	biological_process	DNA recombination
P	0006974	biological_process	DNA damage response
P	0009378	molecular_function	four-way junction helicase activity
P	0009379	cellular_component	Holliday junction helicase complex
P	0009432	biological_process	SOS response
P	0016787	molecular_function	hydrolase activity
P	0016887	molecular_function	ATP hydrolysis activity
P	0048476	cellular_component	Holliday junction resolvase complex
P	0071247	biological_process	cellular response to chromate
P	0072715	biological_process	cellular response to selenite ion

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016

Chain	Residue	Details
M	ILE24
M	ARG295
M	ARG314
M	ARG319
N	ILE24
N	ARG25
N	GLY66
N	LYS69
N	THR70
N	THR71
N	GLU132
M	ARG25
N	ARG175
N	ARG222
N	ARG295
N	ARG314
N	ARG319
O	ILE24
O	ARG25
O	GLY66
O	LYS69
O	THR70
M	GLY66
O	THR71
O	GLU132
O	ARG175
O	ARG222
O	ARG295
O	ARG314
O	ARG319
P	ILE24
P	ARG25
P	GLY66
M	LYS69
P	LYS69
P	THR70
P	THR71
P	GLU132
P	ARG175
P	ARG222
P	ARG295
P	ARG314
P	ARG319
M	THR70
M	THR71
M	GLU132
M	ARG175
M	ARG222

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000312|PDB:6BLB

Chain	Residue	Details
M	ILE33
N	ILE33
O	ILE33
P	ILE33

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016, ECO:0000312|PDB:6BLB

Chain	Residue	Details
M	TYR185
N	TYR185
O	TYR185
P	TYR185

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