7X73
Structure of G9a in complex with RK-701
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002039 | molecular_function | p53 binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0002039 | molecular_function | p53 binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| B | 0042054 | molecular_function | histone methyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS974 | |
| A | MET1048 | |
| A | TYR1085 | |
| A | ASN1112 | |
| A | CYS1115 | |
| A | CYS1168 | |
| A | GLN1169 | |
| A | CYS1170 | |
| A | CYS1175 | |
| B | CYS974 | |
| B | CYS976 | |
| A | CYS976 | |
| B | CYS980 | |
| B | CYS985 | |
| B | CYS987 | |
| B | CYS1017 | |
| B | CYS1021 | |
| B | CYS1023 | |
| B | CYS1027 | |
| B | MET1048 | |
| B | TYR1085 | |
| B | ASN1112 | |
| A | CYS980 | |
| B | CYS1115 | |
| B | CYS1168 | |
| B | GLN1169 | |
| B | CYS1170 | |
| B | CYS1175 | |
| A | CYS985 | |
| A | CYS987 | |
| A | CYS1017 | |
| A | CYS1021 | |
| A | CYS1023 | |
| A | CYS1027 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Histone H3K9me binding => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR1067 | |
| B | TYR1067 |
