7WTF
SARS-CoV-2 Omicron variant spike in complex with Fab XGv051
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0016020 | cellular_component | membrane |
| B | 0019031 | cellular_component | viral envelope |
| B | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| B | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0055036 | cellular_component | virion membrane |
| B | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| C | 0016020 | cellular_component | membrane |
| C | 0019031 | cellular_component | viral envelope |
| C | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| C | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| C | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| C | 0055036 | cellular_component | virion membrane |
| C | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
| D | 0016020 | cellular_component | membrane |
| D | 0019031 | cellular_component | viral envelope |
| D | 0019064 | biological_process | fusion of virus membrane with host plasma membrane |
| D | 0039654 | biological_process | fusion of virus membrane with host endosome membrane |
| D | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| D | 0055036 | cellular_component | virion membrane |
| D | 0075509 | biological_process | endocytosis involved in viral entry into host cell |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| B | ALA687 | |
| C | ALA687 | |
| D | ALA687 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| B | ARG817 | |
| C | ARG817 | |
| D | ARG817 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN17 | |
| B | ASN1160 | |
| C | ASN17 | |
| C | ASN1160 | |
| D | ASN17 | |
| D | ASN1160 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN61 | |
| C | ASN1076 | |
| D | ASN61 | |
| D | THR124 | |
| D | ASN719 | |
| D | ASN803 | |
| D | ASN1076 | |
| B | THR124 | |
| B | ASN719 | |
| B | ASN803 | |
| B | ASN1076 | |
| C | ASN61 | |
| C | THR124 | |
| C | ASN719 | |
| C | ASN803 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | THR76 | |
| B | GLU154 | |
| C | THR76 | |
| C | GLU151 | |
| D | THR76 | |
| D | GLU151 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | TYR170 | |
| C | ASN333 | |
| C | ASN345 | |
| C | ASN618 | |
| C | ASN659 | |
| C | ASN1100 | |
| D | TYR167 | |
| D | ASN284 | |
| D | ASN333 | |
| D | ASN345 | |
| D | ASN618 | |
| B | ASN284 | |
| D | ASN659 | |
| D | ASN1100 | |
| B | ASN333 | |
| B | ASN345 | |
| B | ASN618 | |
| B | ASN659 | |
| B | ASN1100 | |
| C | TYR167 | |
| C | ASN284 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN236 | |
| B | ASN711 | |
| C | ASN233 | |
| C | ASN711 | |
| D | ASN233 | |
| D | ASN711 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| B | THR325 | |
| C | THR325 | |
| D | THR325 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| B | SER327 | |
| C | SER327 | |
| D | SER327 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN605 | |
| C | ASN605 | |
| D | ASN605 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| B | THR678 | |
| B | THR680 | |
| C | THR678 | |
| C | THR680 | |
| D | THR678 | |
| D | THR680 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| B | ASN1136 | |
| C | ASN1136 | |
| D | ASN1136 |
