7W85

Structural of the filamentous Escherichia coli glutamine synthetase

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006541	biological_process	glutamine metabolic process
A	0006542	biological_process	glutamine biosynthetic process
A	0009314	biological_process	response to radiation
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019676	biological_process	ammonia assimilation cycle
A	0019740	biological_process	nitrogen utilization
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006541	biological_process	glutamine metabolic process
B	0006542	biological_process	glutamine biosynthetic process
B	0009314	biological_process	response to radiation
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019676	biological_process	ammonia assimilation cycle
B	0019740	biological_process	nitrogen utilization
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006541	biological_process	glutamine metabolic process
C	0006542	biological_process	glutamine biosynthetic process
C	0009314	biological_process	response to radiation
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0019676	biological_process	ammonia assimilation cycle
C	0019740	biological_process	nitrogen utilization
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006541	biological_process	glutamine metabolic process
D	0006542	biological_process	glutamine biosynthetic process
D	0009314	biological_process	response to radiation
D	0016020	cellular_component	membrane
D	0016874	molecular_function	ligase activity
D	0019676	biological_process	ammonia assimilation cycle
D	0019740	biological_process	nitrogen utilization
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0004356	molecular_function	glutamine synthetase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006541	biological_process	glutamine metabolic process
E	0006542	biological_process	glutamine biosynthetic process
E	0009314	biological_process	response to radiation
E	0016020	cellular_component	membrane
E	0016874	molecular_function	ligase activity
E	0019676	biological_process	ammonia assimilation cycle
E	0019740	biological_process	nitrogen utilization
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0004356	molecular_function	glutamine synthetase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006541	biological_process	glutamine metabolic process
F	0006542	biological_process	glutamine biosynthetic process
F	0009314	biological_process	response to radiation
F	0016020	cellular_component	membrane
F	0016874	molecular_function	ligase activity
F	0019676	biological_process	ammonia assimilation cycle
F	0019740	biological_process	nitrogen utilization
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0004356	molecular_function	glutamine synthetase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006541	biological_process	glutamine metabolic process
G	0006542	biological_process	glutamine biosynthetic process
G	0009314	biological_process	response to radiation
G	0016020	cellular_component	membrane
G	0016874	molecular_function	ligase activity
G	0019676	biological_process	ammonia assimilation cycle
G	0019740	biological_process	nitrogen utilization
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0004356	molecular_function	glutamine synthetase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006541	biological_process	glutamine metabolic process
H	0006542	biological_process	glutamine biosynthetic process
H	0009314	biological_process	response to radiation
H	0016020	cellular_component	membrane
H	0016874	molecular_function	ligase activity
H	0019676	biological_process	ammonia assimilation cycle
H	0019740	biological_process	nitrogen utilization
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0004356	molecular_function	glutamine synthetase activity
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006541	biological_process	glutamine metabolic process
I	0006542	biological_process	glutamine biosynthetic process
I	0009314	biological_process	response to radiation
I	0016020	cellular_component	membrane
I	0016874	molecular_function	ligase activity
I	0019676	biological_process	ammonia assimilation cycle
I	0019740	biological_process	nitrogen utilization
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0004356	molecular_function	glutamine synthetase activity
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006541	biological_process	glutamine metabolic process
J	0006542	biological_process	glutamine biosynthetic process
J	0009314	biological_process	response to radiation
J	0016020	cellular_component	membrane
J	0016874	molecular_function	ligase activity
J	0019676	biological_process	ammonia assimilation cycle
J	0019740	biological_process	nitrogen utilization
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0004356	molecular_function	glutamine synthetase activity
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006541	biological_process	glutamine metabolic process
K	0006542	biological_process	glutamine biosynthetic process
K	0009314	biological_process	response to radiation
K	0016020	cellular_component	membrane
K	0016874	molecular_function	ligase activity
K	0019676	biological_process	ammonia assimilation cycle
K	0019740	biological_process	nitrogen utilization
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006541	biological_process	glutamine metabolic process
L	0006542	biological_process	glutamine biosynthetic process
L	0009314	biological_process	response to radiation
L	0016020	cellular_component	membrane
L	0016874	molecular_function	ligase activity
L	0019676	biological_process	ammonia assimilation cycle
L	0019740	biological_process	nitrogen utilization
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
M	0000166	molecular_function	nucleotide binding
M	0003824	molecular_function	catalytic activity
M	0004356	molecular_function	glutamine synthetase activity
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006541	biological_process	glutamine metabolic process
M	0006542	biological_process	glutamine biosynthetic process
M	0009314	biological_process	response to radiation
M	0016020	cellular_component	membrane
M	0016874	molecular_function	ligase activity
M	0019676	biological_process	ammonia assimilation cycle
M	0019740	biological_process	nitrogen utilization
M	0042802	molecular_function	identical protein binding
M	0046872	molecular_function	metal ion binding
N	0000166	molecular_function	nucleotide binding
N	0003824	molecular_function	catalytic activity
N	0004356	molecular_function	glutamine synthetase activity
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006541	biological_process	glutamine metabolic process
N	0006542	biological_process	glutamine biosynthetic process
N	0009314	biological_process	response to radiation
N	0016020	cellular_component	membrane
N	0016874	molecular_function	ligase activity
N	0019676	biological_process	ammonia assimilation cycle
N	0019740	biological_process	nitrogen utilization
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0004356	molecular_function	glutamine synthetase activity
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006541	biological_process	glutamine metabolic process
O	0006542	biological_process	glutamine biosynthetic process
O	0009314	biological_process	response to radiation
O	0016020	cellular_component	membrane
O	0016874	molecular_function	ligase activity
O	0019676	biological_process	ammonia assimilation cycle
O	0019740	biological_process	nitrogen utilization
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
P	0000166	molecular_function	nucleotide binding
P	0003824	molecular_function	catalytic activity
P	0004356	molecular_function	glutamine synthetase activity
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006541	biological_process	glutamine metabolic process
P	0006542	biological_process	glutamine biosynthetic process
P	0009314	biological_process	response to radiation
P	0016020	cellular_component	membrane
P	0016874	molecular_function	ligase activity
P	0019676	biological_process	ammonia assimilation cycle
P	0019740	biological_process	nitrogen utilization
P	0042802	molecular_function	identical protein binding
P	0046872	molecular_function	metal ion binding
Q	0000166	molecular_function	nucleotide binding
Q	0003824	molecular_function	catalytic activity
Q	0004356	molecular_function	glutamine synthetase activity
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006541	biological_process	glutamine metabolic process
Q	0006542	biological_process	glutamine biosynthetic process
Q	0009314	biological_process	response to radiation
Q	0016020	cellular_component	membrane
Q	0016874	molecular_function	ligase activity
Q	0019676	biological_process	ammonia assimilation cycle
Q	0019740	biological_process	nitrogen utilization
Q	0042802	molecular_function	identical protein binding
Q	0046872	molecular_function	metal ion binding
R	0000166	molecular_function	nucleotide binding
R	0003824	molecular_function	catalytic activity
R	0004356	molecular_function	glutamine synthetase activity
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006541	biological_process	glutamine metabolic process
R	0006542	biological_process	glutamine biosynthetic process
R	0009314	biological_process	response to radiation
R	0016020	cellular_component	membrane
R	0016874	molecular_function	ligase activity
R	0019676	biological_process	ammonia assimilation cycle
R	0019740	biological_process	nitrogen utilization
R	0042802	molecular_function	identical protein binding
R	0046872	molecular_function	metal ion binding
S	0000166	molecular_function	nucleotide binding
S	0003824	molecular_function	catalytic activity
S	0004356	molecular_function	glutamine synthetase activity
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006541	biological_process	glutamine metabolic process
S	0006542	biological_process	glutamine biosynthetic process
S	0009314	biological_process	response to radiation
S	0016020	cellular_component	membrane
S	0016874	molecular_function	ligase activity
S	0019676	biological_process	ammonia assimilation cycle
S	0019740	biological_process	nitrogen utilization
S	0042802	molecular_function	identical protein binding
S	0046872	molecular_function	metal ion binding
U	0000166	molecular_function	nucleotide binding
U	0003824	molecular_function	catalytic activity
U	0004356	molecular_function	glutamine synthetase activity
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006541	biological_process	glutamine metabolic process
U	0006542	biological_process	glutamine biosynthetic process
U	0009314	biological_process	response to radiation
U	0016020	cellular_component	membrane
U	0016874	molecular_function	ligase activity
U	0019676	biological_process	ammonia assimilation cycle
U	0019740	biological_process	nitrogen utilization
U	0042802	molecular_function	identical protein binding
U	0046872	molecular_function	metal ion binding
V	0000166	molecular_function	nucleotide binding
V	0003824	molecular_function	catalytic activity
V	0004356	molecular_function	glutamine synthetase activity
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006541	biological_process	glutamine metabolic process
V	0006542	biological_process	glutamine biosynthetic process
V	0009314	biological_process	response to radiation
V	0016020	cellular_component	membrane
V	0016874	molecular_function	ligase activity
V	0019676	biological_process	ammonia assimilation cycle
V	0019740	biological_process	nitrogen utilization
V	0042802	molecular_function	identical protein binding
V	0046872	molecular_function	metal ion binding
W	0000166	molecular_function	nucleotide binding
W	0003824	molecular_function	catalytic activity
W	0004356	molecular_function	glutamine synthetase activity
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006541	biological_process	glutamine metabolic process
W	0006542	biological_process	glutamine biosynthetic process
W	0009314	biological_process	response to radiation
W	0016020	cellular_component	membrane
W	0016874	molecular_function	ligase activity
W	0019676	biological_process	ammonia assimilation cycle
W	0019740	biological_process	nitrogen utilization
W	0042802	molecular_function	identical protein binding
W	0046872	molecular_function	metal ion binding
X	0000166	molecular_function	nucleotide binding
X	0003824	molecular_function	catalytic activity
X	0004356	molecular_function	glutamine synthetase activity
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006541	biological_process	glutamine metabolic process
X	0006542	biological_process	glutamine biosynthetic process
X	0009314	biological_process	response to radiation
X	0016020	cellular_component	membrane
X	0016874	molecular_function	ligase activity
X	0019676	biological_process	ammonia assimilation cycle
X	0019740	biological_process	nitrogen utilization
X	0042802	molecular_function	identical protein binding
X	0046872	molecular_function	metal ion binding
Y	0000166	molecular_function	nucleotide binding
Y	0003824	molecular_function	catalytic activity
Y	0004356	molecular_function	glutamine synthetase activity
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006541	biological_process	glutamine metabolic process
Y	0006542	biological_process	glutamine biosynthetic process
Y	0009314	biological_process	response to radiation
Y	0016020	cellular_component	membrane
Y	0016874	molecular_function	ligase activity
Y	0019676	biological_process	ammonia assimilation cycle
Y	0019740	biological_process	nitrogen utilization
Y	0042802	molecular_function	identical protein binding
Y	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiggwkginESDmvL

Chain	Residue	Details
A	PHE50-LEU68

---

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMfgd..NGSGmHchmS

Chain	Residue	Details
A	LYS259-SER274

---

site_id	PS00182
Number of Residues	13
Details	GLNA_ADENYLATION Glutamine synthetase class-I adenylation site. KIhpgeaMDKNLY

Chain	Residue	Details
A	LYS386-TYR398

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2016
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	192
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WN39","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	168
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A1P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12425","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P77961","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Modified residue: {"description":"O-AMP-tyrosine","evidences":[{"source":"PubMed","id":"4904088","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"5543675","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---