7W5C
Crystal structure of Mitogen Activated Protein Kinase 4 (MPK4) from Arabidopsis thaliana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000165 | biological_process | MAPK cascade |
| A | 0000911 | biological_process | cytokinesis by cell plate formation |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0004707 | molecular_function | MAP kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0006972 | biological_process | hyperosmotic response |
| A | 0007112 | biological_process | male meiosis cytokinesis |
| A | 0007165 | biological_process | signal transduction |
| A | 0009409 | biological_process | response to cold |
| A | 0009504 | cellular_component | cell plate |
| A | 0009555 | biological_process | pollen development |
| A | 0009620 | biological_process | response to fungus |
| A | 0009651 | biological_process | response to salt stress |
| A | 0009737 | biological_process | response to abscisic acid |
| A | 0009861 | biological_process | jasmonic acid and ethylene-dependent systemic resistance |
| A | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| A | 0009868 | biological_process | jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway |
| A | 0010119 | biological_process | regulation of stomatal movement |
| A | 0010183 | biological_process | pollen tube guidance |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0035556 | biological_process | intracellular signal transduction |
| A | 0042539 | biological_process | hypotonic salinity response |
| A | 0043622 | biological_process | cortical microtubule organization |
| A | 0071244 | biological_process | cellular response to carbon dioxide |
| A | 0090333 | biological_process | regulation of stomatal closure |
| A | 0106310 | molecular_function | protein serine kinase activity |
| A | 2000377 | biological_process | regulation of reactive oxygen species metabolic process |
| Q | 0004672 | molecular_function | protein kinase activity |
| Q | 0005524 | molecular_function | ATP binding |
| Q | 0006468 | biological_process | protein phosphorylation |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGRGAYGIVCaAtnsetgeev.........AIKK |
| Chain | Residue | Details |
| A | ILE49-LYS73 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpsNLLL |
| Chain | Residue | Details |
| A | VAL165-LEU177 |
| site_id | PS01351 |
| Number of Residues | 104 |
| Details | MAPK MAP kinase signature. FdniidakrtlREikllkhmdhenviavkdiikppqrenfndvyivyelmdtdlhqiirsnqpltddhcrfflyqllrglkyvhsanvlh.........RDlKpsnlllnanC |
| Chain | Residue | Details |
| A | PHE78-CYS181 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 286 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Motif: {"description":"TXY"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"11123804","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"11123804","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
