7VG3

Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0003725	molecular_function	double-stranded RNA binding
A	0004386	molecular_function	helicase activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004525	molecular_function	ribonuclease III activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0006396	biological_process	RNA processing
A	0006952	biological_process	defense response
A	0010267	biological_process	ta-siRNA processing
A	0016787	molecular_function	hydrolase activity
A	0030422	biological_process	siRNA processing
A	0031047	biological_process	regulatory ncRNA-mediated gene silencing
A	0044027	biological_process	negative regulation of gene expression via chromosomal CpG island methylation
A	0046872	molecular_function	metal ion binding
A	0051214	biological_process	RNAi-mediated antiviral immunity against RNA virus
A	0051607	biological_process	defense response to virus

Functional Information from PROSITE/UniProt

site_id	PS00517
Number of Residues	9
Details	RNASE_3_1 Ribonuclease III family signature. ERLEFLGDS

Chain	Residue	Details
A	GLU1221-SER1229

site_id	PS01039
Number of Residues	14
Details	SBP_BACTERIAL_3 Bacterial extracellular solute-binding proteins, family 3 signature. GIDVDFDPnLVVEA

Chain	Residue	Details
A	GLY1159-ALA1172

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	172
Details	Domain: {"description":"RNase III 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00177","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details