7V5L

Crystal structure of human bleomycin hydrolase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000209	biological_process	protein polyubiquitination
A	0004177	molecular_function	aminopeptidase activity
A	0004180	molecular_function	carboxypeptidase activity
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008234	molecular_function	cysteine-type peptidase activity
A	0009636	biological_process	response to toxic substance
A	0016787	molecular_function	hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0043418	biological_process	L-homocysteine catabolic process
A	0070005	molecular_function	cysteine-type aminopeptidase activity
A	0070062	cellular_component	extracellular exosome
B	0000209	biological_process	protein polyubiquitination
B	0004177	molecular_function	aminopeptidase activity
B	0004180	molecular_function	carboxypeptidase activity
B	0004197	molecular_function	cysteine-type endopeptidase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008234	molecular_function	cysteine-type peptidase activity
B	0009636	biological_process	response to toxic substance
B	0016787	molecular_function	hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0043418	biological_process	L-homocysteine catabolic process
B	0070005	molecular_function	cysteine-type aminopeptidase activity
B	0070062	cellular_component	extracellular exosome
C	0000209	biological_process	protein polyubiquitination
C	0004177	molecular_function	aminopeptidase activity
C	0004180	molecular_function	carboxypeptidase activity
C	0004197	molecular_function	cysteine-type endopeptidase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008234	molecular_function	cysteine-type peptidase activity
C	0009636	biological_process	response to toxic substance
C	0016787	molecular_function	hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0043418	biological_process	L-homocysteine catabolic process
C	0070005	molecular_function	cysteine-type aminopeptidase activity
C	0070062	cellular_component	extracellular exosome
D	0000209	biological_process	protein polyubiquitination
D	0004177	molecular_function	aminopeptidase activity
D	0004180	molecular_function	carboxypeptidase activity
D	0004197	molecular_function	cysteine-type endopeptidase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008234	molecular_function	cysteine-type peptidase activity
D	0009636	biological_process	response to toxic substance
D	0016787	molecular_function	hydrolase activity
D	0042802	molecular_function	identical protein binding
D	0043418	biological_process	L-homocysteine catabolic process
D	0070005	molecular_function	cysteine-type aminopeptidase activity
D	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00139
Number of Residues	12
Details	THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QKsSGRCWIfSC

Chain	Residue	Details
A	GLN67-CYS78

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Active site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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