7UXU

CryoEM structure of the TIR domain from AbTir in complex with 3AD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction
B	0007165	biological_process	signal transduction
C	0007165	biological_process	signal transduction
D	0007165	biological_process	signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36048923","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7UXU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Site: {"description":"Important for ADPR cyclization","evidences":[{"source":"PubMed","id":"36048923","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---