7UTD

The 2.19-angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - Complex minus stalk

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008901	molecular_function	ferredoxin hydrogenase activity
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0033748	molecular_function	hydrogenase (acceptor) activity
A	0046872	molecular_function	metal ion binding
B	0008901	molecular_function	ferredoxin hydrogenase activity
B	0009055	molecular_function	electron transfer activity
B	0009061	biological_process	anaerobic respiration
B	0009375	cellular_component	ferredoxin hydrogenase complex
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0033748	molecular_function	hydrogenase (acceptor) activity
B	0044569	cellular_component	[Ni-Fe] hydrogenase complex
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051538	molecular_function	3 iron, 4 sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0008901	molecular_function	ferredoxin hydrogenase activity
C	0016151	molecular_function	nickel cation binding
C	0016491	molecular_function	oxidoreductase activity
C	0033748	molecular_function	hydrogenase (acceptor) activity
C	0046872	molecular_function	metal ion binding
D	0008901	molecular_function	ferredoxin hydrogenase activity
D	0009055	molecular_function	electron transfer activity
D	0009061	biological_process	anaerobic respiration
D	0009375	cellular_component	ferredoxin hydrogenase complex
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0033748	molecular_function	hydrogenase (acceptor) activity
D	0044569	cellular_component	[Ni-Fe] hydrogenase complex
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051538	molecular_function	3 iron, 4 sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0008901	molecular_function	ferredoxin hydrogenase activity
E	0016151	molecular_function	nickel cation binding
E	0016491	molecular_function	oxidoreductase activity
E	0033748	molecular_function	hydrogenase (acceptor) activity
E	0046872	molecular_function	metal ion binding
F	0008901	molecular_function	ferredoxin hydrogenase activity
F	0009055	molecular_function	electron transfer activity
F	0009061	biological_process	anaerobic respiration
F	0009375	cellular_component	ferredoxin hydrogenase complex
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0033748	molecular_function	hydrogenase (acceptor) activity
F	0044569	cellular_component	[Ni-Fe] hydrogenase complex
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051538	molecular_function	3 iron, 4 sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	0008901	molecular_function	ferredoxin hydrogenase activity
G	0016151	molecular_function	nickel cation binding
G	0016491	molecular_function	oxidoreductase activity
G	0033748	molecular_function	hydrogenase (acceptor) activity
G	0046872	molecular_function	metal ion binding
H	0008901	molecular_function	ferredoxin hydrogenase activity
H	0009055	molecular_function	electron transfer activity
H	0009061	biological_process	anaerobic respiration
H	0009375	cellular_component	ferredoxin hydrogenase complex
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0033748	molecular_function	hydrogenase (acceptor) activity
H	0044569	cellular_component	[Ni-Fe] hydrogenase complex
H	0046872	molecular_function	metal ion binding
H	0051536	molecular_function	iron-sulfur cluster binding
H	0051538	molecular_function	3 iron, 4 sulfur cluster binding
H	0051539	molecular_function	4 iron, 4 sulfur cluster binding
I	0008901	molecular_function	ferredoxin hydrogenase activity
I	0016151	molecular_function	nickel cation binding
I	0016491	molecular_function	oxidoreductase activity
I	0033748	molecular_function	hydrogenase (acceptor) activity
I	0046872	molecular_function	metal ion binding
J	0008901	molecular_function	ferredoxin hydrogenase activity
J	0009055	molecular_function	electron transfer activity
J	0009061	biological_process	anaerobic respiration
J	0009375	cellular_component	ferredoxin hydrogenase complex
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0033748	molecular_function	hydrogenase (acceptor) activity
J	0044569	cellular_component	[Ni-Fe] hydrogenase complex
J	0046872	molecular_function	metal ion binding
J	0051536	molecular_function	iron-sulfur cluster binding
J	0051538	molecular_function	3 iron, 4 sulfur cluster binding
J	0051539	molecular_function	4 iron, 4 sulfur cluster binding
K	0008901	molecular_function	ferredoxin hydrogenase activity
K	0016151	molecular_function	nickel cation binding
K	0016491	molecular_function	oxidoreductase activity
K	0033748	molecular_function	hydrogenase (acceptor) activity
K	0046872	molecular_function	metal ion binding
L	0008901	molecular_function	ferredoxin hydrogenase activity
L	0009055	molecular_function	electron transfer activity
L	0009061	biological_process	anaerobic respiration
L	0009375	cellular_component	ferredoxin hydrogenase complex
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0033748	molecular_function	hydrogenase (acceptor) activity
L	0044569	cellular_component	[Ni-Fe] hydrogenase complex
L	0046872	molecular_function	metal ion binding
L	0051536	molecular_function	iron-sulfur cluster binding
L	0051538	molecular_function	3 iron, 4 sulfur cluster binding
L	0051539	molecular_function	4 iron, 4 sulfur cluster binding
M	0008901	molecular_function	ferredoxin hydrogenase activity
M	0016151	molecular_function	nickel cation binding
M	0016491	molecular_function	oxidoreductase activity
M	0033748	molecular_function	hydrogenase (acceptor) activity
M	0046872	molecular_function	metal ion binding
N	0008901	molecular_function	ferredoxin hydrogenase activity
N	0009055	molecular_function	electron transfer activity
N	0009061	biological_process	anaerobic respiration
N	0009375	cellular_component	ferredoxin hydrogenase complex
N	0016020	cellular_component	membrane
N	0016491	molecular_function	oxidoreductase activity
N	0033748	molecular_function	hydrogenase (acceptor) activity
N	0044569	cellular_component	[Ni-Fe] hydrogenase complex
N	0046872	molecular_function	metal ion binding
N	0051536	molecular_function	iron-sulfur cluster binding
N	0051538	molecular_function	3 iron, 4 sulfur cluster binding
N	0051539	molecular_function	4 iron, 4 sulfur cluster binding
O	0008901	molecular_function	ferredoxin hydrogenase activity
O	0016151	molecular_function	nickel cation binding
O	0016491	molecular_function	oxidoreductase activity
O	0033748	molecular_function	hydrogenase (acceptor) activity
O	0046872	molecular_function	metal ion binding
P	0008901	molecular_function	ferredoxin hydrogenase activity
P	0009055	molecular_function	electron transfer activity
P	0009061	biological_process	anaerobic respiration
P	0009375	cellular_component	ferredoxin hydrogenase complex
P	0016020	cellular_component	membrane
P	0016491	molecular_function	oxidoreductase activity
P	0033748	molecular_function	hydrogenase (acceptor) activity
P	0044569	cellular_component	[Ni-Fe] hydrogenase complex
P	0046872	molecular_function	metal ion binding
P	0051536	molecular_function	iron-sulfur cluster binding
P	0051538	molecular_function	3 iron, 4 sulfur cluster binding
P	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00507
Number of Residues	26
Details	NI_HGENASE_L_1 Nickel-dependent hydrogenases large subunit signature 1. RGFEiilrgkdpqaglivcPRiCGIC

Chain	Residue	Details
A	ARG40-CYS65

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