7UQK

Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0000166	molecular_function	nucleotide binding
A	0000775	cellular_component	chromosome, centromeric region
A	0000785	cellular_component	chromatin
A	0003682	molecular_function	chromatin binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0005829	cellular_component	cytosol
A	0006261	biological_process	DNA-templated DNA replication
A	0006325	biological_process	chromatin organization
A	0006334	biological_process	nucleosome assembly
A	0006337	biological_process	nucleosome disassembly
A	0006338	biological_process	chromatin remodeling
A	0010468	biological_process	regulation of gene expression
A	0010557	biological_process	positive regulation of macromolecule biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0034080	biological_process	CENP-A containing chromatin assembly
A	0034728	biological_process	nucleosome organization
A	0042393	molecular_function	histone binding
A	0045815	biological_process	transcription initiation-coupled chromatin remodeling
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0065004	biological_process	protein-DNA complex assembly
A	0140658	molecular_function	ATP-dependent chromatin remodeler activity
A	0140674	molecular_function	ATP-dependent histone chaperone activity
A	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0000166	molecular_function	nucleotide binding
B	0000775	cellular_component	chromosome, centromeric region
B	0000785	cellular_component	chromatin
B	0003682	molecular_function	chromatin binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0005829	cellular_component	cytosol
B	0006261	biological_process	DNA-templated DNA replication
B	0006325	biological_process	chromatin organization
B	0006334	biological_process	nucleosome assembly
B	0006337	biological_process	nucleosome disassembly
B	0006338	biological_process	chromatin remodeling
B	0010468	biological_process	regulation of gene expression
B	0010557	biological_process	positive regulation of macromolecule biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0034080	biological_process	CENP-A containing chromatin assembly
B	0034728	biological_process	nucleosome organization
B	0042393	molecular_function	histone binding
B	0045815	biological_process	transcription initiation-coupled chromatin remodeling
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0065004	biological_process	protein-DNA complex assembly
B	0140658	molecular_function	ATP-dependent chromatin remodeler activity
B	0140674	molecular_function	ATP-dependent histone chaperone activity
B	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0000166	molecular_function	nucleotide binding
C	0000775	cellular_component	chromosome, centromeric region
C	0000785	cellular_component	chromatin
C	0003682	molecular_function	chromatin binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0005829	cellular_component	cytosol
C	0006261	biological_process	DNA-templated DNA replication
C	0006325	biological_process	chromatin organization
C	0006334	biological_process	nucleosome assembly
C	0006337	biological_process	nucleosome disassembly
C	0006338	biological_process	chromatin remodeling
C	0010468	biological_process	regulation of gene expression
C	0010557	biological_process	positive regulation of macromolecule biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0034080	biological_process	CENP-A containing chromatin assembly
C	0034728	biological_process	nucleosome organization
C	0042393	molecular_function	histone binding
C	0045815	biological_process	transcription initiation-coupled chromatin remodeling
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0065004	biological_process	protein-DNA complex assembly
C	0140658	molecular_function	ATP-dependent chromatin remodeler activity
C	0140674	molecular_function	ATP-dependent histone chaperone activity
C	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
D	0000122	biological_process	negative regulation of transcription by RNA polymerase II
D	0000166	molecular_function	nucleotide binding
D	0000775	cellular_component	chromosome, centromeric region
D	0000785	cellular_component	chromatin
D	0003682	molecular_function	chromatin binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0005829	cellular_component	cytosol
D	0006261	biological_process	DNA-templated DNA replication
D	0006325	biological_process	chromatin organization
D	0006334	biological_process	nucleosome assembly
D	0006337	biological_process	nucleosome disassembly
D	0006338	biological_process	chromatin remodeling
D	0010468	biological_process	regulation of gene expression
D	0010557	biological_process	positive regulation of macromolecule biosynthetic process
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0034080	biological_process	CENP-A containing chromatin assembly
D	0034728	biological_process	nucleosome organization
D	0042393	molecular_function	histone binding
D	0045815	biological_process	transcription initiation-coupled chromatin remodeling
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0065004	biological_process	protein-DNA complex assembly
D	0140658	molecular_function	ATP-dependent chromatin remodeler activity
D	0140674	molecular_function	ATP-dependent histone chaperone activity
D	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0000166	molecular_function	nucleotide binding
E	0000775	cellular_component	chromosome, centromeric region
E	0000785	cellular_component	chromatin
E	0003682	molecular_function	chromatin binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005694	cellular_component	chromosome
E	0005829	cellular_component	cytosol
E	0006261	biological_process	DNA-templated DNA replication
E	0006325	biological_process	chromatin organization
E	0006334	biological_process	nucleosome assembly
E	0006337	biological_process	nucleosome disassembly
E	0006338	biological_process	chromatin remodeling
E	0010468	biological_process	regulation of gene expression
E	0010557	biological_process	positive regulation of macromolecule biosynthetic process
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0034080	biological_process	CENP-A containing chromatin assembly
E	0034728	biological_process	nucleosome organization
E	0042393	molecular_function	histone binding
E	0045815	biological_process	transcription initiation-coupled chromatin remodeling
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0065004	biological_process	protein-DNA complex assembly
E	0140658	molecular_function	ATP-dependent chromatin remodeler activity
E	0140674	molecular_function	ATP-dependent histone chaperone activity
E	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
F	0000122	biological_process	negative regulation of transcription by RNA polymerase II
F	0000166	molecular_function	nucleotide binding
F	0000775	cellular_component	chromosome, centromeric region
F	0000785	cellular_component	chromatin
F	0003682	molecular_function	chromatin binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005694	cellular_component	chromosome
F	0005829	cellular_component	cytosol
F	0006261	biological_process	DNA-templated DNA replication
F	0006325	biological_process	chromatin organization
F	0006334	biological_process	nucleosome assembly
F	0006337	biological_process	nucleosome disassembly
F	0006338	biological_process	chromatin remodeling
F	0010468	biological_process	regulation of gene expression
F	0010557	biological_process	positive regulation of macromolecule biosynthetic process
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0034080	biological_process	CENP-A containing chromatin assembly
F	0034728	biological_process	nucleosome organization
F	0042393	molecular_function	histone binding
F	0045815	biological_process	transcription initiation-coupled chromatin remodeling
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0065004	biological_process	protein-DNA complex assembly
F	0140658	molecular_function	ATP-dependent chromatin remodeler activity
F	0140674	molecular_function	ATP-dependent histone chaperone activity
F	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation
G	0000122	biological_process	negative regulation of transcription by RNA polymerase II
G	0000166	molecular_function	nucleotide binding
G	0000775	cellular_component	chromosome, centromeric region
G	0000785	cellular_component	chromatin
G	0003682	molecular_function	chromatin binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0005829	cellular_component	cytosol
G	0006261	biological_process	DNA-templated DNA replication
G	0006325	biological_process	chromatin organization
G	0006334	biological_process	nucleosome assembly
G	0006337	biological_process	nucleosome disassembly
G	0006338	biological_process	chromatin remodeling
G	0010468	biological_process	regulation of gene expression
G	0010557	biological_process	positive regulation of macromolecule biosynthetic process
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0034080	biological_process	CENP-A containing chromatin assembly
G	0034728	biological_process	nucleosome organization
G	0042393	molecular_function	histone binding
G	0045815	biological_process	transcription initiation-coupled chromatin remodeling
G	0045944	biological_process	positive regulation of transcription by RNA polymerase II
G	0065004	biological_process	protein-DNA complex assembly
G	0140658	molecular_function	ATP-dependent chromatin remodeler activity
G	0140674	molecular_function	ATP-dependent histone chaperone activity
G	2000219	biological_process	positive regulation of invasive growth in response to glucose limitation

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. ViVIgATNrpdaVDpALr.R

Chain	Residue	Details
A	VAL556-ARG574

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	512
Details	Region: {"description":"AAA-ATPase; required for its chromatin boundary function","evidences":[{"source":"PubMed","id":"22156209","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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