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7UQI

Cryo-EM structure of the S. cerevisiae chromatin remodeler Yta7 hexamer bound to ADP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000775cellular_componentchromosome, centromeric region
A0000785cellular_componentchromatin
A0003682molecular_functionchromatin binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005829cellular_componentcytosol
A0006261biological_processDNA-templated DNA replication
A0006325biological_processchromatin organization
A0006334biological_processnucleosome assembly
A0006337biological_processnucleosome disassembly
A0006338biological_processchromatin remodeling
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0034080biological_processCENP-A containing chromatin assembly
A0042393molecular_functionhistone binding
A0045815biological_processtranscription initiation-coupled chromatin remodeling
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0140658molecular_functionATP-dependent chromatin remodeler activity
A0140674molecular_functionATP-dependent histone chaperone activity
A2000219biological_processpositive regulation of invasive growth in response to glucose limitation
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000775cellular_componentchromosome, centromeric region
B0000785cellular_componentchromatin
B0003682molecular_functionchromatin binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005694cellular_componentchromosome
B0005829cellular_componentcytosol
B0006261biological_processDNA-templated DNA replication
B0006325biological_processchromatin organization
B0006334biological_processnucleosome assembly
B0006337biological_processnucleosome disassembly
B0006338biological_processchromatin remodeling
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0034080biological_processCENP-A containing chromatin assembly
B0042393molecular_functionhistone binding
B0045815biological_processtranscription initiation-coupled chromatin remodeling
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0140658molecular_functionATP-dependent chromatin remodeler activity
B0140674molecular_functionATP-dependent histone chaperone activity
B2000219biological_processpositive regulation of invasive growth in response to glucose limitation
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0000775cellular_componentchromosome, centromeric region
C0000785cellular_componentchromatin
C0003682molecular_functionchromatin binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005694cellular_componentchromosome
C0005829cellular_componentcytosol
C0006261biological_processDNA-templated DNA replication
C0006325biological_processchromatin organization
C0006334biological_processnucleosome assembly
C0006337biological_processnucleosome disassembly
C0006338biological_processchromatin remodeling
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0034080biological_processCENP-A containing chromatin assembly
C0042393molecular_functionhistone binding
C0045815biological_processtranscription initiation-coupled chromatin remodeling
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0140658molecular_functionATP-dependent chromatin remodeler activity
C0140674molecular_functionATP-dependent histone chaperone activity
C2000219biological_processpositive regulation of invasive growth in response to glucose limitation
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0000775cellular_componentchromosome, centromeric region
D0000785cellular_componentchromatin
D0003682molecular_functionchromatin binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005694cellular_componentchromosome
D0005829cellular_componentcytosol
D0006261biological_processDNA-templated DNA replication
D0006325biological_processchromatin organization
D0006334biological_processnucleosome assembly
D0006337biological_processnucleosome disassembly
D0006338biological_processchromatin remodeling
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0034080biological_processCENP-A containing chromatin assembly
D0042393molecular_functionhistone binding
D0045815biological_processtranscription initiation-coupled chromatin remodeling
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0140658molecular_functionATP-dependent chromatin remodeler activity
D0140674molecular_functionATP-dependent histone chaperone activity
D2000219biological_processpositive regulation of invasive growth in response to glucose limitation
E0000122biological_processnegative regulation of transcription by RNA polymerase II
E0000775cellular_componentchromosome, centromeric region
E0000785cellular_componentchromatin
E0003682molecular_functionchromatin binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0005694cellular_componentchromosome
E0005829cellular_componentcytosol
E0006261biological_processDNA-templated DNA replication
E0006325biological_processchromatin organization
E0006334biological_processnucleosome assembly
E0006337biological_processnucleosome disassembly
E0006338biological_processchromatin remodeling
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0034080biological_processCENP-A containing chromatin assembly
E0042393molecular_functionhistone binding
E0045815biological_processtranscription initiation-coupled chromatin remodeling
E0045944biological_processpositive regulation of transcription by RNA polymerase II
E0140658molecular_functionATP-dependent chromatin remodeler activity
E0140674molecular_functionATP-dependent histone chaperone activity
E2000219biological_processpositive regulation of invasive growth in response to glucose limitation
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0000775cellular_componentchromosome, centromeric region
F0000785cellular_componentchromatin
F0003682molecular_functionchromatin binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005694cellular_componentchromosome
F0005829cellular_componentcytosol
F0006261biological_processDNA-templated DNA replication
F0006325biological_processchromatin organization
F0006334biological_processnucleosome assembly
F0006337biological_processnucleosome disassembly
F0006338biological_processchromatin remodeling
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0034080biological_processCENP-A containing chromatin assembly
F0042393molecular_functionhistone binding
F0045815biological_processtranscription initiation-coupled chromatin remodeling
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0140658molecular_functionATP-dependent chromatin remodeler activity
F0140674molecular_functionATP-dependent histone chaperone activity
F2000219biological_processpositive regulation of invasive growth in response to glucose limitation
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000775cellular_componentchromosome, centromeric region
G0000785cellular_componentchromatin
G0003682molecular_functionchromatin binding
G0005524molecular_functionATP binding
G0005634cellular_componentnucleus
G0005694cellular_componentchromosome
G0005829cellular_componentcytosol
G0006261biological_processDNA-templated DNA replication
G0006325biological_processchromatin organization
G0006334biological_processnucleosome assembly
G0006337biological_processnucleosome disassembly
G0006338biological_processchromatin remodeling
G0016787molecular_functionhydrolase activity
G0016887molecular_functionATP hydrolysis activity
G0034080biological_processCENP-A containing chromatin assembly
G0042393molecular_functionhistone binding
G0045815biological_processtranscription initiation-coupled chromatin remodeling
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0140658molecular_functionATP-dependent chromatin remodeler activity
G0140674molecular_functionATP-dependent histone chaperone activity
G2000219biological_processpositive regulation of invasive growth in response to glucose limitation
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0000775cellular_componentchromosome, centromeric region
H0000785cellular_componentchromatin
H0003682molecular_functionchromatin binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005694cellular_componentchromosome
H0005829cellular_componentcytosol
H0006261biological_processDNA-templated DNA replication
H0006325biological_processchromatin organization
H0006334biological_processnucleosome assembly
H0006337biological_processnucleosome disassembly
H0006338biological_processchromatin remodeling
H0016787molecular_functionhydrolase activity
H0016887molecular_functionATP hydrolysis activity
H0034080biological_processCENP-A containing chromatin assembly
H0042393molecular_functionhistone binding
H0045815biological_processtranscription initiation-coupled chromatin remodeling
H0045944biological_processpositive regulation of transcription by RNA polymerase II
H0140658molecular_functionATP-dependent chromatin remodeler activity
H0140674molecular_functionATP-dependent histone chaperone activity
H2000219biological_processpositive regulation of invasive growth in response to glucose limitation
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0000775cellular_componentchromosome, centromeric region
I0000785cellular_componentchromatin
I0003682molecular_functionchromatin binding
I0005524molecular_functionATP binding
I0005634cellular_componentnucleus
I0005694cellular_componentchromosome
I0005829cellular_componentcytosol
I0006261biological_processDNA-templated DNA replication
I0006325biological_processchromatin organization
I0006334biological_processnucleosome assembly
I0006337biological_processnucleosome disassembly
I0006338biological_processchromatin remodeling
I0016787molecular_functionhydrolase activity
I0016887molecular_functionATP hydrolysis activity
I0034080biological_processCENP-A containing chromatin assembly
I0042393molecular_functionhistone binding
I0045815biological_processtranscription initiation-coupled chromatin remodeling
I0045944biological_processpositive regulation of transcription by RNA polymerase II
I0140658molecular_functionATP-dependent chromatin remodeler activity
I0140674molecular_functionATP-dependent histone chaperone activity
I2000219biological_processpositive regulation of invasive growth in response to glucose limitation
Functional Information from PROSITE/UniProt
site_idPS00674
Number of Residues19
DetailsAAA AAA-protein family signature. ViVIgATNrpdaVDpALr.R
ChainResidueDetails
AVAL556-ARG574

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
AGLY455
BGLY454
CGLY454
DGLY454
EGLY454
FGLY454
GGLY454
HGLY454
IGLY454

site_idSWS_FT_FI2
Number of Residues9
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:17287358
ChainResidueDetails
AALA3
BALA2
CALA2
DALA2
EALA2
FALA2
GALA2
HALA2
IALA2

site_idSWS_FT_FI3
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER12
BSER11
CSER11
DSER11
ESER11
FSER11
GSER11
HSER11
ISER11

site_idSWS_FT_FI4
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17287358
ChainResidueDetails
ASER18
BSER17
CSER17
DSER17
ESER17
FSER17
GSER17
HSER17
ISER17

site_idSWS_FT_FI5
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950
ChainResidueDetails
ASER95
BSER94
CSER94
DSER94
ESER94
FSER94
GSER94
HSER94
ISER94

site_idSWS_FT_FI6
Number of Residues9
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ATHR213
BTHR212
CTHR212
DTHR212
ETHR212
FTHR212
GTHR212
HTHR212
ITHR212

site_idSWS_FT_FI7
Number of Residues9
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ATHR230
BTHR229
CTHR229
DTHR229
ETHR229
FTHR229
GTHR229
HTHR229
ITHR229

site_idSWS_FT_FI8
Number of Residues18
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ASER242
ESER285
FSER241
FSER285
GSER241
GSER285
HSER241
HSER285
ISER241
ISER285
ASER286
BSER241
BSER285
CSER241
CSER285
DSER241
DSER285
ESER241

site_idSWS_FT_FI9
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER260
BSER259
CSER259
DSER259
ESER259
FSER259
GSER259
HSER259
ISER259

site_idSWS_FT_FI10
Number of Residues36
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER368
CSER369
CSER370
CSER735
DSER367
DSER369
DSER370
DSER735
ESER367
ESER369
ESER370
ASER370
ESER735
FSER367
FSER369
FSER370
FSER735
GSER367
GSER369
GSER370
GSER735
HSER367
ASER371
HSER369
HSER370
HSER735
ISER367
ISER369
ISER370
ISER735
ASER736
BSER367
BSER369
BSER370
BSER735
CSER367

site_idSWS_FT_FI11
Number of Residues18
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER1143
ESER1256
FSER1142
FSER1256
GSER1142
GSER1256
HSER1142
HSER1256
ISER1142
ISER1256
ASER1257
BSER1142
BSER1256
CSER1142
CSER1256
DSER1142
DSER1256
ESER1142

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PDB entries from 2024-07-24

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