7UNF

CryoEM structure of a mEAK7 bound human V-ATPase complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000139	cellular_component	Golgi membrane
0	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
0	0005515	molecular_function	protein binding
0	0005765	cellular_component	lysosomal membrane
0	0005886	cellular_component	plasma membrane
0	0005925	cellular_component	focal adhesion
0	0007035	biological_process	vacuolar acidification
0	0007042	biological_process	lysosomal lumen acidification
0	0010008	cellular_component	endosome membrane
0	0015078	molecular_function	proton transmembrane transporter activity
0	0015986	biological_process	proton motive force-driven ATP synthesis
0	0016020	cellular_component	membrane
0	0016241	biological_process	regulation of macroautophagy
0	0030177	biological_process	positive regulation of Wnt signaling pathway
0	0030665	cellular_component	clathrin-coated vesicle membrane
0	0030670	cellular_component	phagocytic vesicle membrane
0	0030672	cellular_component	synaptic vesicle membrane
0	0031410	cellular_component	cytoplasmic vesicle
0	0031625	molecular_function	ubiquitin protein ligase binding
0	0033176	cellular_component	proton-transporting V-type ATPase complex
0	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
0	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
0	0035577	cellular_component	azurophil granule membrane
0	0045202	cellular_component	synapse
0	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
0	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
0	0048388	biological_process	endosomal lumen acidification
0	0051452	biological_process	intracellular pH reduction
0	0061795	biological_process	Golgi lumen acidification
0	0070062	cellular_component	extracellular exosome
0	0070821	cellular_component	tertiary granule membrane
0	0101003	cellular_component	ficolin-1-rich granule membrane
0	1902495	cellular_component	transmembrane transporter complex
0	1902600	biological_process	proton transmembrane transport
1	0000139	cellular_component	Golgi membrane
1	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
1	0005515	molecular_function	protein binding
1	0005765	cellular_component	lysosomal membrane
1	0005768	cellular_component	endosome
1	0005886	cellular_component	plasma membrane
1	0007035	biological_process	vacuolar acidification
1	0007042	biological_process	lysosomal lumen acidification
1	0010008	cellular_component	endosome membrane
1	0015078	molecular_function	proton transmembrane transporter activity
1	0016020	cellular_component	membrane
1	0016241	biological_process	regulation of macroautophagy
1	0030665	cellular_component	clathrin-coated vesicle membrane
1	0030670	cellular_component	phagocytic vesicle membrane
1	0031410	cellular_component	cytoplasmic vesicle
1	0033176	cellular_component	proton-transporting V-type ATPase complex
1	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
1	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
1	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
1	0048388	biological_process	endosomal lumen acidification
1	0051452	biological_process	intracellular pH reduction
1	0061795	biological_process	Golgi lumen acidification
1	1902495	cellular_component	transmembrane transporter complex
1	1902600	biological_process	proton transmembrane transport
2	0000139	cellular_component	Golgi membrane
2	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
2	0005515	molecular_function	protein binding
2	0005765	cellular_component	lysosomal membrane
2	0005886	cellular_component	plasma membrane
2	0005925	cellular_component	focal adhesion
2	0007035	biological_process	vacuolar acidification
2	0007042	biological_process	lysosomal lumen acidification
2	0010008	cellular_component	endosome membrane
2	0015078	molecular_function	proton transmembrane transporter activity
2	0015986	biological_process	proton motive force-driven ATP synthesis
2	0016020	cellular_component	membrane
2	0016241	biological_process	regulation of macroautophagy
2	0030177	biological_process	positive regulation of Wnt signaling pathway
2	0030665	cellular_component	clathrin-coated vesicle membrane
2	0030670	cellular_component	phagocytic vesicle membrane
2	0030672	cellular_component	synaptic vesicle membrane
2	0031410	cellular_component	cytoplasmic vesicle
2	0031625	molecular_function	ubiquitin protein ligase binding
2	0033176	cellular_component	proton-transporting V-type ATPase complex
2	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
2	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
2	0035577	cellular_component	azurophil granule membrane
2	0045202	cellular_component	synapse
2	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
2	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
2	0048388	biological_process	endosomal lumen acidification
2	0051452	biological_process	intracellular pH reduction
2	0061795	biological_process	Golgi lumen acidification
2	0070062	cellular_component	extracellular exosome
2	0070821	cellular_component	tertiary granule membrane
2	0101003	cellular_component	ficolin-1-rich granule membrane
2	1902495	cellular_component	transmembrane transporter complex
2	1902600	biological_process	proton transmembrane transport
3	0000139	cellular_component	Golgi membrane
3	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
3	0005515	molecular_function	protein binding
3	0005765	cellular_component	lysosomal membrane
3	0005886	cellular_component	plasma membrane
3	0005925	cellular_component	focal adhesion
3	0007035	biological_process	vacuolar acidification
3	0007042	biological_process	lysosomal lumen acidification
3	0010008	cellular_component	endosome membrane
3	0015078	molecular_function	proton transmembrane transporter activity
3	0015986	biological_process	proton motive force-driven ATP synthesis
3	0016020	cellular_component	membrane
3	0016241	biological_process	regulation of macroautophagy
3	0030177	biological_process	positive regulation of Wnt signaling pathway
3	0030665	cellular_component	clathrin-coated vesicle membrane
3	0030670	cellular_component	phagocytic vesicle membrane
3	0030672	cellular_component	synaptic vesicle membrane
3	0031410	cellular_component	cytoplasmic vesicle
3	0031625	molecular_function	ubiquitin protein ligase binding
3	0033176	cellular_component	proton-transporting V-type ATPase complex
3	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
3	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
3	0035577	cellular_component	azurophil granule membrane
3	0045202	cellular_component	synapse
3	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
3	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
3	0048388	biological_process	endosomal lumen acidification
3	0051452	biological_process	intracellular pH reduction
3	0061795	biological_process	Golgi lumen acidification
3	0070062	cellular_component	extracellular exosome
3	0070821	cellular_component	tertiary granule membrane
3	0101003	cellular_component	ficolin-1-rich granule membrane
3	1902495	cellular_component	transmembrane transporter complex
3	1902600	biological_process	proton transmembrane transport
4	0000139	cellular_component	Golgi membrane
4	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
4	0005515	molecular_function	protein binding
4	0005765	cellular_component	lysosomal membrane
4	0005886	cellular_component	plasma membrane
4	0005925	cellular_component	focal adhesion
4	0007035	biological_process	vacuolar acidification
4	0007042	biological_process	lysosomal lumen acidification
4	0010008	cellular_component	endosome membrane
4	0015078	molecular_function	proton transmembrane transporter activity
4	0015986	biological_process	proton motive force-driven ATP synthesis
4	0016020	cellular_component	membrane
4	0016241	biological_process	regulation of macroautophagy
4	0030177	biological_process	positive regulation of Wnt signaling pathway
4	0030665	cellular_component	clathrin-coated vesicle membrane
4	0030670	cellular_component	phagocytic vesicle membrane
4	0030672	cellular_component	synaptic vesicle membrane
4	0031410	cellular_component	cytoplasmic vesicle
4	0031625	molecular_function	ubiquitin protein ligase binding
4	0033176	cellular_component	proton-transporting V-type ATPase complex
4	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
4	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
4	0035577	cellular_component	azurophil granule membrane
4	0045202	cellular_component	synapse
4	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
4	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
4	0048388	biological_process	endosomal lumen acidification
4	0051452	biological_process	intracellular pH reduction
4	0061795	biological_process	Golgi lumen acidification
4	0070062	cellular_component	extracellular exosome
4	0070821	cellular_component	tertiary granule membrane
4	0101003	cellular_component	ficolin-1-rich granule membrane
4	1902495	cellular_component	transmembrane transporter complex
4	1902600	biological_process	proton transmembrane transport
5	0000139	cellular_component	Golgi membrane
5	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
5	0005515	molecular_function	protein binding
5	0005765	cellular_component	lysosomal membrane
5	0005886	cellular_component	plasma membrane
5	0005925	cellular_component	focal adhesion
5	0007035	biological_process	vacuolar acidification
5	0007042	biological_process	lysosomal lumen acidification
5	0010008	cellular_component	endosome membrane
5	0015078	molecular_function	proton transmembrane transporter activity
5	0015986	biological_process	proton motive force-driven ATP synthesis
5	0016020	cellular_component	membrane
5	0016241	biological_process	regulation of macroautophagy
5	0030177	biological_process	positive regulation of Wnt signaling pathway
5	0030665	cellular_component	clathrin-coated vesicle membrane
5	0030670	cellular_component	phagocytic vesicle membrane
5	0030672	cellular_component	synaptic vesicle membrane
5	0031410	cellular_component	cytoplasmic vesicle
5	0031625	molecular_function	ubiquitin protein ligase binding
5	0033176	cellular_component	proton-transporting V-type ATPase complex
5	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
5	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
5	0035577	cellular_component	azurophil granule membrane
5	0045202	cellular_component	synapse
5	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
5	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
5	0048388	biological_process	endosomal lumen acidification
5	0051452	biological_process	intracellular pH reduction
5	0061795	biological_process	Golgi lumen acidification
5	0070062	cellular_component	extracellular exosome
5	0070821	cellular_component	tertiary granule membrane
5	0101003	cellular_component	ficolin-1-rich granule membrane
5	1902495	cellular_component	transmembrane transporter complex
5	1902600	biological_process	proton transmembrane transport
6	0000139	cellular_component	Golgi membrane
6	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
6	0005515	molecular_function	protein binding
6	0005765	cellular_component	lysosomal membrane
6	0005886	cellular_component	plasma membrane
6	0005925	cellular_component	focal adhesion
6	0007035	biological_process	vacuolar acidification
6	0007042	biological_process	lysosomal lumen acidification
6	0010008	cellular_component	endosome membrane
6	0015078	molecular_function	proton transmembrane transporter activity
6	0015986	biological_process	proton motive force-driven ATP synthesis
6	0016020	cellular_component	membrane
6	0016241	biological_process	regulation of macroautophagy
6	0030177	biological_process	positive regulation of Wnt signaling pathway
6	0030665	cellular_component	clathrin-coated vesicle membrane
6	0030670	cellular_component	phagocytic vesicle membrane
6	0030672	cellular_component	synaptic vesicle membrane
6	0031410	cellular_component	cytoplasmic vesicle
6	0031625	molecular_function	ubiquitin protein ligase binding
6	0033176	cellular_component	proton-transporting V-type ATPase complex
6	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
6	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
6	0035577	cellular_component	azurophil granule membrane
6	0045202	cellular_component	synapse
6	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
6	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
6	0048388	biological_process	endosomal lumen acidification
6	0051452	biological_process	intracellular pH reduction
6	0061795	biological_process	Golgi lumen acidification
6	0070062	cellular_component	extracellular exosome
6	0070821	cellular_component	tertiary granule membrane
6	0101003	cellular_component	ficolin-1-rich granule membrane
6	1902495	cellular_component	transmembrane transporter complex
6	1902600	biological_process	proton transmembrane transport
7	0000139	cellular_component	Golgi membrane
7	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
7	0005515	molecular_function	protein binding
7	0005765	cellular_component	lysosomal membrane
7	0005886	cellular_component	plasma membrane
7	0005925	cellular_component	focal adhesion
7	0007035	biological_process	vacuolar acidification
7	0007042	biological_process	lysosomal lumen acidification
7	0010008	cellular_component	endosome membrane
7	0015078	molecular_function	proton transmembrane transporter activity
7	0015986	biological_process	proton motive force-driven ATP synthesis
7	0016020	cellular_component	membrane
7	0016241	biological_process	regulation of macroautophagy
7	0030177	biological_process	positive regulation of Wnt signaling pathway
7	0030665	cellular_component	clathrin-coated vesicle membrane
7	0030670	cellular_component	phagocytic vesicle membrane
7	0030672	cellular_component	synaptic vesicle membrane
7	0031410	cellular_component	cytoplasmic vesicle
7	0031625	molecular_function	ubiquitin protein ligase binding
7	0033176	cellular_component	proton-transporting V-type ATPase complex
7	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
7	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
7	0035577	cellular_component	azurophil granule membrane
7	0045202	cellular_component	synapse
7	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
7	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
7	0048388	biological_process	endosomal lumen acidification
7	0051452	biological_process	intracellular pH reduction
7	0061795	biological_process	Golgi lumen acidification
7	0070062	cellular_component	extracellular exosome
7	0070821	cellular_component	tertiary granule membrane
7	0101003	cellular_component	ficolin-1-rich granule membrane
7	1902495	cellular_component	transmembrane transporter complex
7	1902600	biological_process	proton transmembrane transport
8	0000139	cellular_component	Golgi membrane
8	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
8	0005515	molecular_function	protein binding
8	0005765	cellular_component	lysosomal membrane
8	0005886	cellular_component	plasma membrane
8	0005925	cellular_component	focal adhesion
8	0007035	biological_process	vacuolar acidification
8	0007042	biological_process	lysosomal lumen acidification
8	0010008	cellular_component	endosome membrane
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0016020	cellular_component	membrane
8	0016241	biological_process	regulation of macroautophagy
8	0030177	biological_process	positive regulation of Wnt signaling pathway
8	0030665	cellular_component	clathrin-coated vesicle membrane
8	0030670	cellular_component	phagocytic vesicle membrane
8	0030672	cellular_component	synaptic vesicle membrane
8	0031410	cellular_component	cytoplasmic vesicle
8	0031625	molecular_function	ubiquitin protein ligase binding
8	0033176	cellular_component	proton-transporting V-type ATPase complex
8	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
8	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
8	0035577	cellular_component	azurophil granule membrane
8	0045202	cellular_component	synapse
8	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
8	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
8	0048388	biological_process	endosomal lumen acidification
8	0051452	biological_process	intracellular pH reduction
8	0061795	biological_process	Golgi lumen acidification
8	0070062	cellular_component	extracellular exosome
8	0070821	cellular_component	tertiary granule membrane
8	0101003	cellular_component	ficolin-1-rich granule membrane
8	1902495	cellular_component	transmembrane transporter complex
8	1902600	biological_process	proton transmembrane transport
9	0000139	cellular_component	Golgi membrane
9	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
9	0005515	molecular_function	protein binding
9	0005765	cellular_component	lysosomal membrane
9	0005886	cellular_component	plasma membrane
9	0005925	cellular_component	focal adhesion
9	0007035	biological_process	vacuolar acidification
9	0007042	biological_process	lysosomal lumen acidification
9	0010008	cellular_component	endosome membrane
9	0015078	molecular_function	proton transmembrane transporter activity
9	0015986	biological_process	proton motive force-driven ATP synthesis
9	0016020	cellular_component	membrane
9	0016241	biological_process	regulation of macroautophagy
9	0030177	biological_process	positive regulation of Wnt signaling pathway
9	0030665	cellular_component	clathrin-coated vesicle membrane
9	0030670	cellular_component	phagocytic vesicle membrane
9	0030672	cellular_component	synaptic vesicle membrane
9	0031410	cellular_component	cytoplasmic vesicle
9	0031625	molecular_function	ubiquitin protein ligase binding
9	0033176	cellular_component	proton-transporting V-type ATPase complex
9	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
9	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
9	0035577	cellular_component	azurophil granule membrane
9	0045202	cellular_component	synapse
9	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
9	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
9	0048388	biological_process	endosomal lumen acidification
9	0051452	biological_process	intracellular pH reduction
9	0061795	biological_process	Golgi lumen acidification
9	0070062	cellular_component	extracellular exosome
9	0070821	cellular_component	tertiary granule membrane
9	0101003	cellular_component	ficolin-1-rich granule membrane
9	1902495	cellular_component	transmembrane transporter complex
9	1902600	biological_process	proton transmembrane transport
a	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
a	0001503	biological_process	ossification
a	0005515	molecular_function	protein binding
a	0005765	cellular_component	lysosomal membrane
a	0005768	cellular_component	endosome
a	0005886	cellular_component	plasma membrane
a	0005903	cellular_component	brush border
a	0006885	biological_process	regulation of pH
a	0007035	biological_process	vacuolar acidification
a	0007605	biological_process	sensory perception of sound
a	0010008	cellular_component	endosome membrane
a	0016323	cellular_component	basolateral plasma membrane
a	0016324	cellular_component	apical plasma membrane
a	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
a	0030670	cellular_component	phagocytic vesicle membrane
a	0030672	cellular_component	synaptic vesicle membrane
a	0031526	cellular_component	brush border membrane
a	0033176	cellular_component	proton-transporting V-type ATPase complex
a	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
a	0045177	cellular_component	apical part of cell
a	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
a	0051117	molecular_function	ATPase binding
a	0051452	biological_process	intracellular pH reduction
a	0070062	cellular_component	extracellular exosome
a	0097254	biological_process	renal tubular secretion
a	0097401	biological_process	synaptic vesicle lumen acidification
a	1902600	biological_process	proton transmembrane transport
b	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
b	0005515	molecular_function	protein binding
b	0005737	cellular_component	cytoplasm
b	0005765	cellular_component	lysosomal membrane
b	0005768	cellular_component	endosome
b	0005829	cellular_component	cytosol
b	0005886	cellular_component	plasma membrane
b	0005902	cellular_component	microvillus
b	0016241	biological_process	regulation of macroautophagy
b	0016324	cellular_component	apical plasma membrane
b	0016469	cellular_component	proton-transporting two-sector ATPase complex
b	0030665	cellular_component	clathrin-coated vesicle membrane
b	0030672	cellular_component	synaptic vesicle membrane
b	0031410	cellular_component	cytoplasmic vesicle
b	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
b	0045202	cellular_component	synapse
b	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
b	0051117	molecular_function	ATPase binding
b	0070062	cellular_component	extracellular exosome
b	0097401	biological_process	synaptic vesicle lumen acidification
b	1902600	biological_process	proton transmembrane transport
c	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
c	0005515	molecular_function	protein binding
c	0005737	cellular_component	cytoplasm
c	0005765	cellular_component	lysosomal membrane
c	0005768	cellular_component	endosome
c	0005829	cellular_component	cytosol
c	0005886	cellular_component	plasma membrane
c	0005902	cellular_component	microvillus
c	0016241	biological_process	regulation of macroautophagy
c	0016324	cellular_component	apical plasma membrane
c	0016469	cellular_component	proton-transporting two-sector ATPase complex
c	0030665	cellular_component	clathrin-coated vesicle membrane
c	0030672	cellular_component	synaptic vesicle membrane
c	0031410	cellular_component	cytoplasmic vesicle
c	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
c	0045202	cellular_component	synapse
c	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
c	0051117	molecular_function	ATPase binding
c	0070062	cellular_component	extracellular exosome
c	0097401	biological_process	synaptic vesicle lumen acidification
c	1902600	biological_process	proton transmembrane transport
C	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
C	0005515	molecular_function	protein binding
C	0005765	cellular_component	lysosomal membrane
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0015078	molecular_function	proton transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0016241	biological_process	regulation of macroautophagy
C	0016469	cellular_component	proton-transporting two-sector ATPase complex
C	0030665	cellular_component	clathrin-coated vesicle membrane
C	0030672	cellular_component	synaptic vesicle membrane
C	0031410	cellular_component	cytoplasmic vesicle
C	0033176	cellular_component	proton-transporting V-type ATPase complex
C	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
C	0045177	cellular_component	apical part of cell
C	0045202	cellular_component	synapse
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	0070062	cellular_component	extracellular exosome
C	0097401	biological_process	synaptic vesicle lumen acidification
C	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
C	1902495	cellular_component	transmembrane transporter complex
C	1902600	biological_process	proton transmembrane transport
C	1904949	cellular_component	ATPase complex
d	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
d	0005515	molecular_function	protein binding
d	0005737	cellular_component	cytoplasm
d	0005765	cellular_component	lysosomal membrane
d	0005768	cellular_component	endosome
d	0005829	cellular_component	cytosol
d	0005886	cellular_component	plasma membrane
d	0005902	cellular_component	microvillus
d	0016241	biological_process	regulation of macroautophagy
d	0016324	cellular_component	apical plasma membrane
d	0016469	cellular_component	proton-transporting two-sector ATPase complex
d	0030665	cellular_component	clathrin-coated vesicle membrane
d	0030672	cellular_component	synaptic vesicle membrane
d	0031410	cellular_component	cytoplasmic vesicle
d	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
d	0045202	cellular_component	synapse
d	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
d	0051117	molecular_function	ATPase binding
d	0070062	cellular_component	extracellular exosome
d	0097401	biological_process	synaptic vesicle lumen acidification
d	1902600	biological_process	proton transmembrane transport
D	0000139	cellular_component	Golgi membrane
D	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
D	0005515	molecular_function	protein binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005765	cellular_component	lysosomal membrane
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005886	cellular_component	plasma membrane
D	0005929	cellular_component	cilium
D	0007035	biological_process	vacuolar acidification
D	0007042	biological_process	lysosomal lumen acidification
D	0010008	cellular_component	endosome membrane
D	0016020	cellular_component	membrane
D	0016241	biological_process	regulation of macroautophagy
D	0030030	biological_process	cell projection organization
D	0030665	cellular_component	clathrin-coated vesicle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0033176	cellular_component	proton-transporting V-type ATPase complex
D	0035579	cellular_component	specific granule membrane
D	0042995	cellular_component	cell projection
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	0048388	biological_process	endosomal lumen acidification
D	0051452	biological_process	intracellular pH reduction
D	0060271	biological_process	cilium assembly
D	0061512	biological_process	protein localization to cilium
D	0061795	biological_process	Golgi lumen acidification
D	0070062	cellular_component	extracellular exosome
D	0097401	biological_process	synaptic vesicle lumen acidification
D	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
D	1902495	cellular_component	transmembrane transporter complex
D	1902600	biological_process	proton transmembrane transport
e	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
e	0005515	molecular_function	protein binding
e	0005765	cellular_component	lysosomal membrane
e	0005829	cellular_component	cytosol
e	0005886	cellular_component	plasma membrane
e	0006879	biological_process	intracellular iron ion homeostasis
e	0016241	biological_process	regulation of macroautophagy
e	0016324	cellular_component	apical plasma membrane
e	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
e	0016887	molecular_function	ATP hydrolysis activity
e	0030672	cellular_component	synaptic vesicle membrane
e	0033176	cellular_component	proton-transporting V-type ATPase complex
e	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
e	0036295	biological_process	cellular response to increased oxygen levels
e	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
e	0051117	molecular_function	ATPase binding
e	0070062	cellular_component	extracellular exosome
e	0097401	biological_process	synaptic vesicle lumen acidification
e	1902495	cellular_component	transmembrane transporter complex
e	1902600	biological_process	proton transmembrane transport
e	1904949	cellular_component	ATPase complex
f	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
f	0005515	molecular_function	protein binding
f	0005765	cellular_component	lysosomal membrane
f	0005829	cellular_component	cytosol
f	0005886	cellular_component	plasma membrane
f	0006879	biological_process	intracellular iron ion homeostasis
f	0016241	biological_process	regulation of macroautophagy
f	0016324	cellular_component	apical plasma membrane
f	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
f	0016887	molecular_function	ATP hydrolysis activity
f	0030672	cellular_component	synaptic vesicle membrane
f	0033176	cellular_component	proton-transporting V-type ATPase complex
f	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
f	0036295	biological_process	cellular response to increased oxygen levels
f	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
f	0051117	molecular_function	ATPase binding
f	0070062	cellular_component	extracellular exosome
f	0097401	biological_process	synaptic vesicle lumen acidification
f	1902495	cellular_component	transmembrane transporter complex
f	1902600	biological_process	proton transmembrane transport
f	1904949	cellular_component	ATPase complex
F	0000139	cellular_component	Golgi membrane
F	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
F	0005515	molecular_function	protein binding
F	0005765	cellular_component	lysosomal membrane
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0007035	biological_process	vacuolar acidification
F	0007042	biological_process	lysosomal lumen acidification
F	0010008	cellular_component	endosome membrane
F	0015078	molecular_function	proton transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
F	0030665	cellular_component	clathrin-coated vesicle membrane
F	0030672	cellular_component	synaptic vesicle membrane
F	0031410	cellular_component	cytoplasmic vesicle
F	0033176	cellular_component	proton-transporting V-type ATPase complex
F	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042625	molecular_function	ATPase-coupled ion transmembrane transporter activity
F	0045202	cellular_component	synapse
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	0048388	biological_process	endosomal lumen acidification
F	0051452	biological_process	intracellular pH reduction
F	0061795	biological_process	Golgi lumen acidification
F	0070062	cellular_component	extracellular exosome
F	0097401	biological_process	synaptic vesicle lumen acidification
F	1902495	cellular_component	transmembrane transporter complex
F	1902600	biological_process	proton transmembrane transport
g	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
g	0005515	molecular_function	protein binding
g	0005765	cellular_component	lysosomal membrane
g	0005829	cellular_component	cytosol
g	0005886	cellular_component	plasma membrane
g	0006879	biological_process	intracellular iron ion homeostasis
g	0016241	biological_process	regulation of macroautophagy
g	0016324	cellular_component	apical plasma membrane
g	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
g	0016887	molecular_function	ATP hydrolysis activity
g	0030672	cellular_component	synaptic vesicle membrane
g	0033176	cellular_component	proton-transporting V-type ATPase complex
g	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
g	0036295	biological_process	cellular response to increased oxygen levels
g	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
g	0051117	molecular_function	ATPase binding
g	0070062	cellular_component	extracellular exosome
g	0097401	biological_process	synaptic vesicle lumen acidification
g	1902495	cellular_component	transmembrane transporter complex
g	1902600	biological_process	proton transmembrane transport
g	1904949	cellular_component	ATPase complex
H	0000139	cellular_component	Golgi membrane
H	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
H	0005515	molecular_function	protein binding
H	0005765	cellular_component	lysosomal membrane
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006897	biological_process	endocytosis
H	0007035	biological_process	vacuolar acidification
H	0007042	biological_process	lysosomal lumen acidification
H	0010008	cellular_component	endosome membrane
H	0016020	cellular_component	membrane
H	0016241	biological_process	regulation of macroautophagy
H	0016887	molecular_function	ATP hydrolysis activity
H	0030234	molecular_function	enzyme regulator activity
H	0030665	cellular_component	clathrin-coated vesicle membrane
H	0031410	cellular_component	cytoplasmic vesicle
H	0033176	cellular_component	proton-transporting V-type ATPase complex
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	0048388	biological_process	endosomal lumen acidification
H	0051452	biological_process	intracellular pH reduction
H	0061795	biological_process	Golgi lumen acidification
H	0070062	cellular_component	extracellular exosome
H	0097401	biological_process	synaptic vesicle lumen acidification
H	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
H	1902495	cellular_component	transmembrane transporter complex
H	1902600	biological_process	proton transmembrane transport
k	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
k	0005515	molecular_function	protein binding
k	0005764	cellular_component	lysosome
k	0005765	cellular_component	lysosomal membrane
k	0005768	cellular_component	endosome
k	0005769	cellular_component	early endosome
k	0005813	cellular_component	centrosome
k	0006879	biological_process	intracellular iron ion homeostasis
k	0007034	biological_process	vacuolar transport
k	0007035	biological_process	vacuolar acidification
k	0008021	cellular_component	synaptic vesicle
k	0010008	cellular_component	endosome membrane
k	0016020	cellular_component	membrane
k	0016241	biological_process	regulation of macroautophagy
k	0016324	cellular_component	apical plasma membrane
k	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
k	0030030	biological_process	cell projection organization
k	0030665	cellular_component	clathrin-coated vesicle membrane
k	0030670	cellular_component	phagocytic vesicle membrane
k	0030672	cellular_component	synaptic vesicle membrane
k	0031410	cellular_component	cytoplasmic vesicle
k	0032991	cellular_component	protein-containing complex
k	0033176	cellular_component	proton-transporting V-type ATPase complex
k	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
k	0033181	cellular_component	plasma membrane proton-transporting V-type ATPase complex
k	0036295	biological_process	cellular response to increased oxygen levels
k	0043679	cellular_component	axon terminus
k	0044877	molecular_function	protein-containing complex binding
k	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
k	0060271	biological_process	cilium assembly
k	0070062	cellular_component	extracellular exosome
k	0097401	biological_process	synaptic vesicle lumen acidification
k	1902495	cellular_component	transmembrane transporter complex
k	1902600	biological_process	proton transmembrane transport
L	0000139	cellular_component	Golgi membrane
L	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005764	cellular_component	lysosome
L	0005765	cellular_component	lysosomal membrane
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0005902	cellular_component	microvillus
L	0006879	biological_process	intracellular iron ion homeostasis
L	0007035	biological_process	vacuolar acidification
L	0007042	biological_process	lysosomal lumen acidification
L	0010008	cellular_component	endosome membrane
L	0015986	biological_process	proton motive force-driven ATP synthesis
L	0016020	cellular_component	membrane
L	0016241	biological_process	regulation of macroautophagy
L	0016324	cellular_component	apical plasma membrane
L	0016469	cellular_component	proton-transporting two-sector ATPase complex
L	0016887	molecular_function	ATP hydrolysis activity
L	0030133	cellular_component	transport vesicle
L	0030141	cellular_component	secretory granule
L	0030665	cellular_component	clathrin-coated vesicle membrane
L	0031090	cellular_component	organelle membrane
L	0031410	cellular_component	cytoplasmic vesicle
L	0033176	cellular_component	proton-transporting V-type ATPase complex
L	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
L	0036295	biological_process	cellular response to increased oxygen levels
L	0043231	cellular_component	intracellular membrane-bounded organelle
L	0046034	biological_process	ATP metabolic process
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	0048388	biological_process	endosomal lumen acidification
L	0051452	biological_process	intracellular pH reduction
L	0061795	biological_process	Golgi lumen acidification
L	0070062	cellular_component	extracellular exosome
L	0097401	biological_process	synaptic vesicle lumen acidification
L	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
L	1902495	cellular_component	transmembrane transporter complex
L	1902600	biological_process	proton transmembrane transport
L	1904949	cellular_component	ATPase complex
m	0005515	molecular_function	protein binding
m	0005765	cellular_component	lysosomal membrane
m	0007035	biological_process	vacuolar acidification
m	0010008	cellular_component	endosome membrane
m	0016020	cellular_component	membrane
m	0016241	biological_process	regulation of macroautophagy
m	0030670	cellular_component	phagocytic vesicle membrane
m	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
m	0042625	molecular_function	ATPase-coupled ion transmembrane transporter activity
m	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
m	0055085	biological_process	transmembrane transport
m	1902600	biological_process	proton transmembrane transport
M	0000139	cellular_component	Golgi membrane
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005764	cellular_component	lysosome
M	0005765	cellular_component	lysosomal membrane
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0005902	cellular_component	microvillus
M	0006879	biological_process	intracellular iron ion homeostasis
M	0007035	biological_process	vacuolar acidification
M	0007042	biological_process	lysosomal lumen acidification
M	0010008	cellular_component	endosome membrane
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0016020	cellular_component	membrane
M	0016241	biological_process	regulation of macroautophagy
M	0016324	cellular_component	apical plasma membrane
M	0016469	cellular_component	proton-transporting two-sector ATPase complex
M	0016887	molecular_function	ATP hydrolysis activity
M	0030133	cellular_component	transport vesicle
M	0030141	cellular_component	secretory granule
M	0030665	cellular_component	clathrin-coated vesicle membrane
M	0031090	cellular_component	organelle membrane
M	0031410	cellular_component	cytoplasmic vesicle
M	0033176	cellular_component	proton-transporting V-type ATPase complex
M	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
M	0036295	biological_process	cellular response to increased oxygen levels
M	0043231	cellular_component	intracellular membrane-bounded organelle
M	0046034	biological_process	ATP metabolic process
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0048388	biological_process	endosomal lumen acidification
M	0051452	biological_process	intracellular pH reduction
M	0061795	biological_process	Golgi lumen acidification
M	0070062	cellular_component	extracellular exosome
M	0097401	biological_process	synaptic vesicle lumen acidification
M	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
M	1902495	cellular_component	transmembrane transporter complex
M	1902600	biological_process	proton transmembrane transport
M	1904949	cellular_component	ATPase complex
n	0000139	cellular_component	Golgi membrane
n	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
n	0004519	molecular_function	endonuclease activity
n	0004521	molecular_function	RNA endonuclease activity
n	0005515	molecular_function	protein binding
n	0005765	cellular_component	lysosomal membrane
n	0005886	cellular_component	plasma membrane
n	0006897	biological_process	endocytosis
n	0006898	biological_process	receptor-mediated endocytosis
n	0007035	biological_process	vacuolar acidification
n	0007042	biological_process	lysosomal lumen acidification
n	0010008	cellular_component	endosome membrane
n	0012505	cellular_component	endomembrane system
n	0016020	cellular_component	membrane
n	0019065	biological_process	receptor-mediated endocytosis of virus by host cell
n	0030665	cellular_component	clathrin-coated vesicle membrane
n	0031410	cellular_component	cytoplasmic vesicle
n	0033176	cellular_component	proton-transporting V-type ATPase complex
n	0048388	biological_process	endosomal lumen acidification
n	0051452	biological_process	intracellular pH reduction
n	0061795	biological_process	Golgi lumen acidification
n	0090304	biological_process	nucleic acid metabolic process
n	1902600	biological_process	proton transmembrane transport
N	0000139	cellular_component	Golgi membrane
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005764	cellular_component	lysosome
N	0005765	cellular_component	lysosomal membrane
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0005902	cellular_component	microvillus
N	0006879	biological_process	intracellular iron ion homeostasis
N	0007035	biological_process	vacuolar acidification
N	0007042	biological_process	lysosomal lumen acidification
N	0010008	cellular_component	endosome membrane
N	0015986	biological_process	proton motive force-driven ATP synthesis
N	0016020	cellular_component	membrane
N	0016241	biological_process	regulation of macroautophagy
N	0016324	cellular_component	apical plasma membrane
N	0016469	cellular_component	proton-transporting two-sector ATPase complex
N	0016887	molecular_function	ATP hydrolysis activity
N	0030133	cellular_component	transport vesicle
N	0030141	cellular_component	secretory granule
N	0030665	cellular_component	clathrin-coated vesicle membrane
N	0031090	cellular_component	organelle membrane
N	0031410	cellular_component	cytoplasmic vesicle
N	0033176	cellular_component	proton-transporting V-type ATPase complex
N	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
N	0036295	biological_process	cellular response to increased oxygen levels
N	0043231	cellular_component	intracellular membrane-bounded organelle
N	0046034	biological_process	ATP metabolic process
N	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0048388	biological_process	endosomal lumen acidification
N	0051452	biological_process	intracellular pH reduction
N	0061795	biological_process	Golgi lumen acidification
N	0070062	cellular_component	extracellular exosome
N	0097401	biological_process	synaptic vesicle lumen acidification
N	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
N	1902495	cellular_component	transmembrane transporter complex
N	1902600	biological_process	proton transmembrane transport
N	1904949	cellular_component	ATPase complex
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0001726	cellular_component	ruffle
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005765	cellular_component	lysosomal membrane
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0005902	cellular_component	microvillus
O	0007035	biological_process	vacuolar acidification
O	0015078	molecular_function	proton transmembrane transporter activity
O	0016241	biological_process	regulation of macroautophagy
O	0016324	cellular_component	apical plasma membrane
O	0016469	cellular_component	proton-transporting two-sector ATPase complex
O	0030665	cellular_component	clathrin-coated vesicle membrane
O	0030672	cellular_component	synaptic vesicle membrane
O	0031090	cellular_component	organelle membrane
O	0031410	cellular_component	cytoplasmic vesicle
O	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
O	0042470	cellular_component	melanosome
O	0043231	cellular_component	intracellular membrane-bounded organelle
O	0045202	cellular_component	synapse
O	0046034	biological_process	ATP metabolic process
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0070062	cellular_component	extracellular exosome
O	0097401	biological_process	synaptic vesicle lumen acidification
O	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
O	1902600	biological_process	proton transmembrane transport
P	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
P	0001726	cellular_component	ruffle
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005765	cellular_component	lysosomal membrane
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0005902	cellular_component	microvillus
P	0007035	biological_process	vacuolar acidification
P	0015078	molecular_function	proton transmembrane transporter activity
P	0016241	biological_process	regulation of macroautophagy
P	0016324	cellular_component	apical plasma membrane
P	0016469	cellular_component	proton-transporting two-sector ATPase complex
P	0030665	cellular_component	clathrin-coated vesicle membrane
P	0030672	cellular_component	synaptic vesicle membrane
P	0031090	cellular_component	organelle membrane
P	0031410	cellular_component	cytoplasmic vesicle
P	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
P	0042470	cellular_component	melanosome
P	0043231	cellular_component	intracellular membrane-bounded organelle
P	0045202	cellular_component	synapse
P	0046034	biological_process	ATP metabolic process
P	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
P	0070062	cellular_component	extracellular exosome
P	0097401	biological_process	synaptic vesicle lumen acidification
P	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
P	1902600	biological_process	proton transmembrane transport
Q	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
Q	0001726	cellular_component	ruffle
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005765	cellular_component	lysosomal membrane
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0005902	cellular_component	microvillus
Q	0007035	biological_process	vacuolar acidification
Q	0015078	molecular_function	proton transmembrane transporter activity
Q	0016241	biological_process	regulation of macroautophagy
Q	0016324	cellular_component	apical plasma membrane
Q	0016469	cellular_component	proton-transporting two-sector ATPase complex
Q	0030665	cellular_component	clathrin-coated vesicle membrane
Q	0030672	cellular_component	synaptic vesicle membrane
Q	0031090	cellular_component	organelle membrane
Q	0031410	cellular_component	cytoplasmic vesicle
Q	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
Q	0042470	cellular_component	melanosome
Q	0043231	cellular_component	intracellular membrane-bounded organelle
Q	0045202	cellular_component	synapse
Q	0046034	biological_process	ATP metabolic process
Q	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
Q	0070062	cellular_component	extracellular exosome
Q	0097401	biological_process	synaptic vesicle lumen acidification
Q	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
Q	1902600	biological_process	proton transmembrane transport
r	0016020	cellular_component	membrane
r	0038023	molecular_function	signaling receptor activity

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSVNWLISYS

Chain	Residue	Details
L	PRO446-SER455
O	PRO390-SER399

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylthreonine => ECO:0000269|Ref.4, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:25944712

Chain	Residue	Details
C	THR2
3	MET1-TYR10
3	ALA77-GLN92
3	SER153-LYS155
4	MET1-TYR10
4	ALA77-GLN92
4	SER153-LYS155
5	MET1-TYR10
5	ALA77-GLN92
5	SER153-LYS155
6	MET1-TYR10
f	ALA2
6	ALA77-GLN92
6	SER153-LYS155
7	MET1-TYR10
7	ALA77-GLN92
7	SER153-LYS155
0	MET1-TYR10
0	ALA77-GLN92
0	SER153-LYS155
g	ALA2
a	ARG663-THR727
a	PHE813-GLU840
9	SER153-LYS155
2	MET1-TYR10
2	ALA77-GLN92
2	SER153-LYS155

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P50518

Chain	Residue	Details
b	TYR56
2	ILE56-ILE76
2	LEU93-GLY114
2	ILE132-LEU152
3	ALA11-GLY33
3	ILE56-ILE76
3	LEU93-GLY114
3	ILE132-LEU152
4	ALA11-GLY33
4	ILE56-ILE76
4	LEU93-GLY114
c	TYR56
4	ILE132-LEU152
5	ALA11-GLY33
5	ILE56-ILE76
5	LEU93-GLY114
5	ILE132-LEU152
6	ALA11-GLY33
6	ILE56-ILE76
6	LEU93-GLY114
6	ILE132-LEU152
7	ALA11-GLY33
d	TYR56
7	ILE56-ILE76
7	LEU93-GLY114
7	ILE132-LEU152
0	ALA11-GLY33
0	ILE56-ILE76
0	LEU93-GLY114
0	ILE132-LEU152
1	PHE138-VAL158
1	ILE176-LEU196
a	PHE643-LEU662
a	ILE728-ALA752
a	GLY774-GLU812
2	ALA11-GLY33

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphoserine; by AMPK => ECO:0007744|PubMed:23186163

Chain	Residue	Details
L	SER384
4	ASP115-MET131
5	THR34-SER55
5	ASP115-MET131
6	THR34-SER55
6	ASP115-MET131
7	THR34-SER55
7	ASP115-MET131
0	THR34-SER55
0	ASP115-MET131
M	SER384
N	SER384
a	GLN753-GLY773
2	THR34-SER55
2	ASP115-MET131
3	THR34-SER55
3	ASP115-MET131
4	THR34-SER55

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Essential for proton translocation => ECO:0000250|UniProtKB:Q2TA24

Chain	Residue	Details
1	GLU98
9	GLU139
2	GLU139
3	GLU139
4	GLU139
5	GLU139
6	GLU139
7	GLU139
0	GLU139

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
s	SER465

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
s	ASN170

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:33065002, ECO:0007744|PDB:6WLW, ECO:0007744|PDB:6WM2, ECO:0007744|PDB:6WM3, ECO:0007744|PDB:6WM4

Chain	Residue	Details
s	ASN261
s	ASN273

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255, ECO:0000269|PubMed:33065002, ECO:0007744|PDB:6WM3, ECO:0007744|PDB:6WM4

Chain	Residue	Details
s	ASN296

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33065002, ECO:0007744|PDB:6WLW, ECO:0007744|PDB:6WM2, ECO:0007744|PDB:6WM3, ECO:0007744|PDB:6WM4

Chain	Residue	Details
s	ASN303
s	ASN350

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:33065002, ECO:0007744|PDB:6WM3, ECO:0007744|PDB:6WM4

Chain	Residue	Details
s	ASN357

---