7ULV

Human DDAH1 soaked with its inactivator S-((4-chloropyridin-2-yl)methyl)-L-cysteine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000052	biological_process	citrulline metabolic process
A	0003073	biological_process	regulation of systemic arterial blood pressure
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0006525	biological_process	arginine metabolic process
A	0006527	biological_process	L-arginine catabolic process
A	0007263	biological_process	nitric oxide mediated signal transduction
A	0008285	biological_process	negative regulation of cell population proliferation
A	0016403	molecular_function	dimethylargininase activity
A	0016597	molecular_function	amino acid binding
A	0016787	molecular_function	hydrolase activity
A	0030235	molecular_function	nitric-oxide synthase regulator activity
A	0043116	biological_process	negative regulation of vascular permeability
A	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
A	0045766	biological_process	positive regulation of angiogenesis
A	0046209	biological_process	nitric oxide metabolic process
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
A	1900038	biological_process	negative regulation of cellular response to hypoxia
B	0000052	biological_process	citrulline metabolic process
B	0003073	biological_process	regulation of systemic arterial blood pressure
B	0003824	molecular_function	catalytic activity
B	0005829	cellular_component	cytosol
B	0006525	biological_process	arginine metabolic process
B	0006527	biological_process	L-arginine catabolic process
B	0007263	biological_process	nitric oxide mediated signal transduction
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016403	molecular_function	dimethylargininase activity
B	0016597	molecular_function	amino acid binding
B	0016787	molecular_function	hydrolase activity
B	0030235	molecular_function	nitric-oxide synthase regulator activity
B	0043116	biological_process	negative regulation of vascular permeability
B	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
B	0045766	biological_process	positive regulation of angiogenesis
B	0046209	biological_process	nitric oxide metabolic process
B	0046872	molecular_function	metal ion binding
B	0070062	cellular_component	extracellular exosome
B	1900038	biological_process	negative regulation of cellular response to hypoxia
C	0000052	biological_process	citrulline metabolic process
C	0003073	biological_process	regulation of systemic arterial blood pressure
C	0003824	molecular_function	catalytic activity
C	0005829	cellular_component	cytosol
C	0006525	biological_process	arginine metabolic process
C	0006527	biological_process	L-arginine catabolic process
C	0007263	biological_process	nitric oxide mediated signal transduction
C	0008285	biological_process	negative regulation of cell population proliferation
C	0016403	molecular_function	dimethylargininase activity
C	0016597	molecular_function	amino acid binding
C	0016787	molecular_function	hydrolase activity
C	0030235	molecular_function	nitric-oxide synthase regulator activity
C	0043116	biological_process	negative regulation of vascular permeability
C	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
C	0045766	biological_process	positive regulation of angiogenesis
C	0046209	biological_process	nitric oxide metabolic process
C	0046872	molecular_function	metal ion binding
C	0070062	cellular_component	extracellular exosome
C	1900038	biological_process	negative regulation of cellular response to hypoxia
D	0000052	biological_process	citrulline metabolic process
D	0003073	biological_process	regulation of systemic arterial blood pressure
D	0003824	molecular_function	catalytic activity
D	0005829	cellular_component	cytosol
D	0006525	biological_process	arginine metabolic process
D	0006527	biological_process	L-arginine catabolic process
D	0007263	biological_process	nitric oxide mediated signal transduction
D	0008285	biological_process	negative regulation of cell population proliferation
D	0016403	molecular_function	dimethylargininase activity
D	0016597	molecular_function	amino acid binding
D	0016787	molecular_function	hydrolase activity
D	0030235	molecular_function	nitric-oxide synthase regulator activity
D	0043116	biological_process	negative regulation of vascular permeability
D	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
D	0045766	biological_process	positive regulation of angiogenesis
D	0046209	biological_process	nitric oxide metabolic process
D	0046872	molecular_function	metal ion binding
D	0070062	cellular_component	extracellular exosome
D	1900038	biological_process	negative regulation of cellular response to hypoxia
E	0000052	biological_process	citrulline metabolic process
E	0003073	biological_process	regulation of systemic arterial blood pressure
E	0003824	molecular_function	catalytic activity
E	0005829	cellular_component	cytosol
E	0006525	biological_process	arginine metabolic process
E	0006527	biological_process	L-arginine catabolic process
E	0007263	biological_process	nitric oxide mediated signal transduction
E	0008285	biological_process	negative regulation of cell population proliferation
E	0016403	molecular_function	dimethylargininase activity
E	0016597	molecular_function	amino acid binding
E	0016787	molecular_function	hydrolase activity
E	0030235	molecular_function	nitric-oxide synthase regulator activity
E	0043116	biological_process	negative regulation of vascular permeability
E	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
E	0045766	biological_process	positive regulation of angiogenesis
E	0046209	biological_process	nitric oxide metabolic process
E	0046872	molecular_function	metal ion binding
E	0070062	cellular_component	extracellular exosome
E	1900038	biological_process	negative regulation of cellular response to hypoxia
F	0000052	biological_process	citrulline metabolic process
F	0003073	biological_process	regulation of systemic arterial blood pressure
F	0003824	molecular_function	catalytic activity
F	0005829	cellular_component	cytosol
F	0006525	biological_process	arginine metabolic process
F	0006527	biological_process	L-arginine catabolic process
F	0007263	biological_process	nitric oxide mediated signal transduction
F	0008285	biological_process	negative regulation of cell population proliferation
F	0016403	molecular_function	dimethylargininase activity
F	0016597	molecular_function	amino acid binding
F	0016787	molecular_function	hydrolase activity
F	0030235	molecular_function	nitric-oxide synthase regulator activity
F	0043116	biological_process	negative regulation of vascular permeability
F	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
F	0045766	biological_process	positive regulation of angiogenesis
F	0046209	biological_process	nitric oxide metabolic process
F	0046872	molecular_function	metal ion binding
F	0070062	cellular_component	extracellular exosome
F	1900038	biological_process	negative regulation of cellular response to hypoxia

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"19663506","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19663506","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	12
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"P56965","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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