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7ULI

Apo HMG-CoA Reductase from Arabidopsis thaliana (HMG1)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
AAA0004420molecular_functionhydroxymethylglutaryl-CoA reductase (NADPH) activity
AAA0005515molecular_functionprotein binding
AAA0005777cellular_componentperoxisome
AAA0005778cellular_componentperoxisomal membrane
AAA0005783cellular_componentendoplasmic reticulum
AAA0005789cellular_componentendoplasmic reticulum membrane
AAA0008299biological_processisoprenoid biosynthetic process
AAA0009536cellular_componentplastid
AAA0015936biological_processcoenzyme A metabolic process
AAA0016020cellular_componentmembrane
AAA0016126biological_processsterol biosynthetic process
AAA0016491molecular_functionoxidoreductase activity
AAA0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
AAA0019287biological_processisopentenyl diphosphate biosynthetic process, mevalonate pathway
Functional Information from PROSITE/UniProt
site_idPS00066
Number of Residues15
DetailsHMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. RfCCsTGDaMGmNmV
ChainResidueDetails
AAAARG352-VAL366

site_idPS00318
Number of Residues8
DetailsHMG_COA_REDUCTASE_2 Hydroxymethylglutaryl-coenzyme A reductases signature 2. VGtVGGGT
ChainResidueDetails
AAAVAL507-THR514

site_idPS01192
Number of Residues14
DetailsHMG_COA_REDUCTASE_3 Hydroxymethylglutaryl-coenzyme A reductases signature 3. AIaAgqLvRSHMkY
ChainResidueDetails
AAAALA561-TYR574

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsActive site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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