7ULI
Apo HMG-CoA Reductase from Arabidopsis thaliana (HMG1)
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004420 | molecular_function | hydroxymethylglutaryl-CoA reductase (NADPH) activity |
| AAA | 0005515 | molecular_function | protein binding |
| AAA | 0005777 | cellular_component | peroxisome |
| AAA | 0005783 | cellular_component | endoplasmic reticulum |
| AAA | 0005789 | cellular_component | endoplasmic reticulum membrane |
| AAA | 0008299 | biological_process | isoprenoid biosynthetic process |
| AAA | 0009536 | cellular_component | plastid |
| AAA | 0015936 | biological_process | coenzyme A metabolic process |
| AAA | 0016020 | cellular_component | membrane |
| AAA | 0016126 | biological_process | sterol biosynthetic process |
| AAA | 0016491 | molecular_function | oxidoreductase activity |
| AAA | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| AAA | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PROSITE/UniProt
| site_id | PS00066 |
| Number of Residues | 15 |
| Details | HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. RfCCsTGDaMGmNmV |
| Chain | Residue | Details |
| AAA | ARG352-VAL366 |
| site_id | PS00318 |
| Number of Residues | 8 |
| Details | HMG_COA_REDUCTASE_2 Hydroxymethylglutaryl-coenzyme A reductases signature 2. VGtVGGGT |
| Chain | Residue | Details |
| AAA | VAL507-THR514 |
| site_id | PS01192 |
| Number of Residues | 14 |
| Details | HMG_COA_REDUCTASE_3 Hydroxymethylglutaryl-coenzyme A reductases signature 3. AIaAgqLvRSHMkY |
| Chain | Residue | Details |
| AAA | ALA561-TYR574 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| AAA | ALA47-VAL69 | |
| AAA | ALA97-VAL117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| AAA | GLU265 | |
| AAA | LYS397 | |
| AAA | ASP473 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU10003 |
| Chain | Residue | Details |
| AAA | HIS571 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:10318703, ECO:0000269|PubMed:28263378, ECO:0000269|PubMed:7588795 |
| Chain | Residue | Details |
| AAA | SER577 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| AAA | ASN16 | |
| AAA | ASN19 | |
| AAA | ASN329 | |
| AAA | ASN575 |
