7UCW

Structure of mouse Decr1 in complex with 2'-5' oligoadenylate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005654	cellular_component	nucleoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
A	0016491	molecular_function	oxidoreductase activity
A	0042802	molecular_function	identical protein binding
A	0070402	molecular_function	NADPH binding
A	0120162	biological_process	positive regulation of cold-induced thermogenesis
A	1902494	cellular_component	catalytic complex
B	0005654	cellular_component	nucleoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
B	0016491	molecular_function	oxidoreductase activity
B	0042802	molecular_function	identical protein binding
B	0070402	molecular_function	NADPH binding
B	0120162	biological_process	positive regulation of cold-induced thermogenesis
B	1902494	cellular_component	catalytic complex
C	0005654	cellular_component	nucleoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
C	0016491	molecular_function	oxidoreductase activity
C	0042802	molecular_function	identical protein binding
C	0070402	molecular_function	NADPH binding
C	0120162	biological_process	positive regulation of cold-induced thermogenesis
C	1902494	cellular_component	catalytic complex
D	0005654	cellular_component	nucleoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006631	biological_process	fatty acid metabolic process
D	0006635	biological_process	fatty acid beta-oxidation
D	0008670	molecular_function	2,4-dienoyl-CoA reductase (NADPH) activity
D	0016491	molecular_function	oxidoreductase activity
D	0042802	molecular_function	identical protein binding
D	0070402	molecular_function	NADPH binding
D	0120162	biological_process	positive regulation of cold-induced thermogenesis
D	1902494	cellular_component	catalytic complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255

Chain	Residue	Details
A	TYR199
B	TYR199
C	TYR199
D	TYR199

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q16698

Chain	Residue	Details
A	GLY66
B	PHE149
B	LYS214
B	PRO240
C	GLY66
C	ASP117
C	ARG119
C	PHE149
C	LYS214
C	PRO240
D	GLY66
A	ASP117
D	ASP117
D	ARG119
D	PHE149
D	LYS214
D	PRO240
A	ARG119
A	PHE149
A	LYS214
A	PRO240
B	GLY66
B	ASP117
B	ARG119

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG91
A	ARG251
B	ARG91
B	ARG251
C	ARG91
C	ARG251
D	ARG91
D	ARG251

---

site_id	SWS_FT_FI4
Number of Residues	28
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS42
B	LYS97
B	LYS106
B	LYS244
B	LYS260
B	LYS319
C	LYS42
C	LYS49
C	LYS97
C	LYS106
C	LYS244
A	LYS49
C	LYS260
C	LYS319
D	LYS42
D	LYS49
D	LYS97
D	LYS106
D	LYS244
D	LYS260
D	LYS319
A	LYS97
A	LYS106
A	LYS244
A	LYS260
A	LYS319
B	LYS42
B	LYS49

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q16698

Chain	Residue	Details
A	THR69
B	THR69
C	THR69
D	THR69

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0007744|PubMed:23806337

Chain	Residue	Details
A	LYS73
B	LYS73
C	LYS73
D	LYS73

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:23576753

Chain	Residue	Details
A	LYS315
B	LYS315
C	LYS315
D	LYS315

---