7U9I

Co-crystal structure of human CARM1 in complex with MT556 inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016274	molecular_function	protein-arginine N-methyltransferase activity
A	0018216	biological_process	peptidyl-arginine methylation
B	0016274	molecular_function	protein-arginine N-methyltransferase activity
B	0018216	biological_process	peptidyl-arginine methylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000305|PubMed:21410432

Chain	Residue	Details
A	GLN159
B	GLU214
B	GLU243
B	SER271
A	ARG168
A	GLY192
A	GLU214
A	GLU243
A	SER271
B	GLN159
B	ARG168
B	GLY192

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:19843527

Chain	Residue	Details
A	SER216
B	SER216

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:34480022

Chain	Residue	Details
A	LYS227
B	LYS227

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