7U5T

Structure of DHQS/EPSPS dimer from Candida albicans Aro1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0003855	molecular_function	3-dehydroquinate dehydratase activity
A	0003856	molecular_function	3-dehydroquinate synthase activity
A	0003866	molecular_function	3-phosphoshikimate 1-carboxyvinyltransferase activity
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0004765	molecular_function	shikimate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0015801	biological_process	aromatic amino acid transport
A	0016301	molecular_function	kinase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding
A	0071466	biological_process	cellular response to xenobiotic stimulus
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0003855	molecular_function	3-dehydroquinate dehydratase activity
B	0003856	molecular_function	3-dehydroquinate synthase activity
B	0003866	molecular_function	3-phosphoshikimate 1-carboxyvinyltransferase activity
B	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
B	0004765	molecular_function	shikimate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0015801	biological_process	aromatic amino acid transport
B	0016301	molecular_function	kinase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0016829	molecular_function	lyase activity
B	0046872	molecular_function	metal ion binding
B	0071466	biological_process	cellular response to xenobiotic stimulus

Functional Information from PROSITE/UniProt

site_id	PS00104
Number of Residues	15
Details	EPSP_SYNTHASE_1 EPSP synthase signature 1. LYlGNAGTASRfLtT

Chain	Residue	Details
A	LEU497-THR511

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site_id	PS00107
Number of Residues	31
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGAGGTSRAAiYalhqmgcakiylvnr...TAAK

Chain	Residue	Details
A	VAL1413-LYS1443

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site_id	PS00885
Number of Residues	19
Details	EPSP_SYNTHASE_2 EPSP synthase signature 2. RvKECNRIeAMvteLakFG

Chain	Residue	Details
A	ARG761-GLY779

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor; for 3-dehydroquinate synthase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	58
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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