7TW8

Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SAH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004482	molecular_function	mRNA 5'-cap (guanine-N7-)-methyltransferase activity
A	0004532	molecular_function	RNA exonuclease activity
A	0008168	molecular_function	methyltransferase activity
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01299","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36546776","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Breakpoint for translocation to form ETV6-MDS2 in MDS"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Breakpoint for translocation to form PAX5-ETV6"}

Chain

Residue

Details

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