7TL7

1.90A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a macrocyclic peptide inhibitor (Sa-D2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004619	molecular_function	phosphoglycerate mutase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006007	biological_process	glucose catabolic process
A	0006096	biological_process	glycolytic process
A	0016853	molecular_function	isomerase activity
A	0030145	molecular_function	manganese ion binding
A	0046537	molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004619	molecular_function	phosphoglycerate mutase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006007	biological_process	glucose catabolic process
B	0006096	biological_process	glycolytic process
B	0016853	molecular_function	isomerase activity
B	0030145	molecular_function	manganese ion binding
B	0046537	molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004619	molecular_function	phosphoglycerate mutase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006007	biological_process	glucose catabolic process
C	0006096	biological_process	glycolytic process
C	0016853	molecular_function	isomerase activity
C	0030145	molecular_function	manganese ion binding
C	0046537	molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004619	molecular_function	phosphoglycerate mutase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006007	biological_process	glucose catabolic process
D	0006096	biological_process	glycolytic process
D	0016853	molecular_function	isomerase activity
D	0030145	molecular_function	manganese ion binding
D	0046537	molecular_function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
D	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q9X519

Chain	Residue	Details
A	SER86
B	SER86
C	SER86
D	SER86

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site_id	SWS_FT_FI2
Number of Residues	52
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9X519

Chain	Residue	Details
A	ASP37
A	HIS430
A	ASP467
A	HIS468
A	HIS485
B	ASP37
B	SER86
B	HIS147
B	ARG177
B	ARG210
B	ARG216
A	SER86
B	ARG284
B	LYS359
B	ASP426
B	HIS430
B	ASP467
B	HIS468
B	HIS485
C	ASP37
C	SER86
C	HIS147
A	HIS147
C	ARG177
C	ARG210
C	ARG216
C	ARG284
C	LYS359
C	ASP426
C	HIS430
C	ASP467
C	HIS468
C	HIS485
A	ARG177
D	ASP37
D	SER86
D	HIS147
D	ARG177
D	ARG210
D	ARG216
D	ARG284
D	LYS359
D	ASP426
D	HIS430
A	ARG210
D	ASP467
D	HIS468
D	HIS485
A	ARG216
A	ARG284
A	LYS359
A	ASP426

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