7T7T
Structure of TSK/BRU1 bound to histone H3.1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0006325 | biological_process | chromatin organization |
| A | 0009933 | biological_process | meristem structural organization |
| A | 0040029 | biological_process | epigenetic regulation of gene expression |
| A | 0072423 | biological_process | response to DNA damage checkpoint signaling |
| B | 0005634 | cellular_component | nucleus |
| B | 0006325 | biological_process | chromatin organization |
| B | 0009933 | biological_process | meristem structural organization |
| B | 0040029 | biological_process | epigenetic regulation of gene expression |
| B | 0072423 | biological_process | response to DNA damage checkpoint signaling |
| W | 0000786 | cellular_component | nucleosome |
| W | 0003677 | molecular_function | DNA binding |
| W | 0030527 | molecular_function | structural constituent of chromatin |
| W | 0046982 | molecular_function | protein heterodimerization activity |
| X | 0000786 | cellular_component | nucleosome |
| X | 0003677 | molecular_function | DNA binding |
| X | 0030527 | molecular_function | structural constituent of chromatin |
| X | 0046982 | molecular_function | protein heterodimerization activity |
Functional Information from PROSITE/UniProt
| site_id | PS00322 |
| Number of Residues | 7 |
| Details | HISTONE_H3_1 Histone H3 signature 1. KAPRKQL |
| Chain | Residue | Details |
| X | LYS14-LEU20 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"TPR 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00339","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Not N6-acetylated","evidences":[{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Required for interaction with TSK","evidences":[{"source":"PubMed","id":"35298257","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"12581305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14712277","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16258034","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"12456661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12581305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14712277","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15014946","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"14712277","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17174094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17439305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19503079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24626927","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35298257","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"14610360","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15753571","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"15598823","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16299497","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
