7S7K

Crystal structure of the EphB2 extracellular domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005003	molecular_function	ephrin receptor activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
A	0007169	biological_process	cell surface receptor protein tyrosine kinase signaling pathway
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00790
Number of Residues	21
Details	RECEPTOR_TYR_KIN_V_1 Receptor tyrosine kinase class V signature 1. FqDyGGCMSLIAVRVfyrKCP

Chain	Residue	Details
A	PHE178-PRO198

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site_id	PS00791
Number of Residues	21
Details	RECEPTOR_TYR_KIN_V_2 Receptor tyrosine kinase class V signature 2. CngDGEWlv.PIGrCmCkaGFE

Chain	Residue	Details
A	CYS241-GLU261

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site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CmCkaGFeavengtvC

Chain	Residue	Details
A	CYS254-CYS269

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	524
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
A	VAL19-LEU543

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Cleavage; by a metalloproteinase => ECO:0000269|PubMed:17428795

Chain	Residue	Details
A	THR535

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN265

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN336
A	ASN428

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19656770

Chain	Residue	Details
A	ASN482

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