7S6U

Leishmania infantum Glycogen Synthase Kinase 3 beta bound to AZD5438

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004712	molecular_function	protein serine/threonine/tyrosine kinase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006468	biological_process	protein phosphorylation
A	0008286	biological_process	insulin receptor signaling pathway
A	0010975	biological_process	regulation of neuron projection development
A	0030424	cellular_component	axon
A	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
A	0097192	biological_process	extrinsic apoptotic signaling pathway in absence of ligand

Functional Information from PROSITE/UniProt

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VcHrDIKphNVLV

Chain	Residue	Details
A	VAL147-VAL159

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