Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7S0S

M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0015934	cellular_component	large ribosomal subunit
b	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0006364	biological_process	rRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0008649	molecular_function	rRNA methyltransferase activity
B	0016020	cellular_component	membrane
B	0019836	biological_process	hemolysis by symbiont of host erythrocytes
B	0020002	cellular_component	host cell plasma membrane
B	0031167	biological_process	rRNA methylation
B	0031640	biological_process	killing of cells of another organism
B	0032259	biological_process	methylation
B	0035821	biological_process	modulation of process of another organism
B	0042254	biological_process	ribosome biogenesis
B	0090729	molecular_function	toxin activity
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0015934	cellular_component	large ribosomal subunit
c	1990904	cellular_component	ribonucleoprotein complex
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015934	cellular_component	large ribosomal subunit
D	0016740	molecular_function	transferase activity
D	0019843	molecular_function	rRNA binding
D	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	1990904	cellular_component	ribonucleoprotein complex
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	1990904	cellular_component	ribonucleoprotein complex
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0043229	cellular_component	intracellular organelle
g	1990904	cellular_component	ribonucleoprotein complex
G	0000049	molecular_function	tRNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	1990904	cellular_component	ribonucleoprotein complex
h	0003735	molecular_function	structural constituent of ribosome
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	1990904	cellular_component	ribonucleoprotein complex
J	0003735	molecular_function	structural constituent of ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0019843	molecular_function	rRNA binding
K	0070180	molecular_function	large ribosomal subunit rRNA binding
K	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005737	cellular_component	cytoplasm
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0043229	cellular_component	intracellular organelle
L	1990904	cellular_component	ribonucleoprotein complex
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015934	cellular_component	large ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015934	cellular_component	large ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0000049	molecular_function	tRNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0019843	molecular_function	rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0043229	cellular_component	intracellular organelle
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0000027	biological_process	ribosomal large subunit assembly
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0019843	molecular_function	rRNA binding
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
T	0043229	cellular_component	intracellular organelle
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015934	cellular_component	large ribosomal subunit
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0019843	molecular_function	rRNA binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0019843	molecular_function	rRNA binding
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0008097	molecular_function	5S rRNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtvkerrra.DGsyikFdeNaaVI

Chain	Residue	Details
M	ALA60-ILE86

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KRAIVKLAagskpidL

Chain	Residue	Details
V	LYS80-LEU95

site_id	PS00359
Number of Residues	15
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. KiIaGTarSMGiTV.E

Chain	Residue	Details
K	LYS128-GLU142

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriRpRAqGRafrirkrtSHITViV

Chain	Residue	Details
U	LYS90-VAL114

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGVVmNPvD

Chain	Residue	Details
D	PRO219-ASP230

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FsdgayvDvtGtSkGKGfaGtmkR

Chain	Residue	Details
E	PHE106-ARG129

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGdGkLtvk..VdVtankFSgsAreaItaaG

Chain	Residue	Details
N	LYS111-GLY141

site_id	PS00525
Number of Residues	9
Details	RIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PDpYKGKGV

Chain	Residue	Details
H	PRO155-VAL163

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NNRRLRtVRQEIARV

Chain	Residue	Details
a	ASN43-VAL57

site_id	PS00582
Number of Residues	20
Details	RIBOSOMAL_L33 Ribosomal protein L33 signature. YiTkKNrrndPdrLEikKFC

Chain	Residue	Details
d	TYR23-CYS42

site_id	PS00586
Number of Residues	12
Details	RIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRgGKVWINIFP

Chain	Residue	Details
O	LYS59-PRO70

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. SLrtLgLkKirQsVvrednaqtrgLIntVhhLV

Chain	Residue	Details
b	SER22-VAL54

site_id	PS00651
Number of Residues	28
Details	RIBOSOMAL_L9 Ribosomal protein L9 signature. GaaGdtveVkdGYgrNYLlprglAivaS

Chain	Residue	Details
I	GLY13-SER40

site_id	PS00701
Number of Residues	12
Details	RIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGsGKGspewW

Chain	Residue	Details
O	ARG82-TRP93

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpnnrrRarvh.GFrlR

Chain	Residue	Details
e	LYS5-ARG24

site_id	PS00828
Number of Residues	26
Details	RIBOSOMAL_L36 Ribosomal protein L36 signature. CdkCrvIrRhgrVmViCsdp.RHkQrQ

Chain	Residue	Details
g	CYS11-GLN36

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GeILvRQRGthfhpG

Chain	Residue	Details
Y	GLY34-GLY48

site_id	PS00936
Number of Residues	27
Details	RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHsGAsKRFrrtgtgkivrqkanr.RH

Chain	Residue	Details
f	LYS5-HIS31

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KgefRkLWISRINaaaR

Chain	Residue	Details
S	LYS54-ARG70

site_id	PS01015
Number of Residues	16
Details	RIBOSOMAL_L19 Ribosomal protein L19 signature. VlTrGDVR.RAKLYYLR

Chain	Residue	Details
R	VAL85-ARG100

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVlVIsGkdKGak.GkV

Chain	Residue	Details
W	GLY6-VAL23

site_id	PS01109
Number of Residues	35
Details	RIBOSOMAL_L10 Ribosomal protein L10 signature. KatAvadIAeqfkastatVvtEyrGLTVaNLaeLR

Chain	Residue	Details
J	LYS6-ARG40

site_id	PS01167
Number of Residues	23
Details	RIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTepKaRalrpyaEkLIThAK

Chain	Residue	Details
P	ILE34-LYS56

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. IrihKfknKTgyhkrqGHRQqlT

Chain	Residue	Details
T	ILE73-THR95

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269\|PubMed:20094657

Chain	Residue	Details
K	LYS101
h	CYS18
h	CYS38
h	CYS41

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)