Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7RJE

Complex III2 from Candida albicans, Inz-5 bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A	0006412	biological_process	translation
A	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
A	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
A	0009060	biological_process	aerobic respiration
A	0045275	cellular_component	respiratory chain complex III
A	0045333	biological_process	cellular respiration
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005886	cellular_component	plasma membrane
B	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B	0006412	biological_process	translation
B	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
B	0009060	biological_process	aerobic respiration
B	0016020	cellular_component	membrane
B	0030061	cellular_component	mitochondrial crista
B	0045275	cellular_component	respiratory chain complex III
B	0045333	biological_process	cellular respiration
B	0046872	molecular_function	metal ion binding
B	1902600	biological_process	proton transmembrane transport
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005886	cellular_component	plasma membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0006412	biological_process	translation
C	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C	0009060	biological_process	aerobic respiration
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0045275	cellular_component	respiratory chain complex III
C	0045333	biological_process	cellular respiration
C	0046872	molecular_function	metal ion binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	1902600	biological_process	proton transmembrane transport
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005886	cellular_component	plasma membrane
D	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
D	0009055	molecular_function	electron transfer activity
D	0020037	molecular_function	heme binding
D	0045275	cellular_component	respiratory chain complex III
D	0045333	biological_process	cellular respiration
D	0046872	molecular_function	metal ion binding
D	1902600	biological_process	proton transmembrane transport
E	0004222	molecular_function	metalloendopeptidase activity
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
E	0006412	biological_process	translation
E	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
E	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
E	0009060	biological_process	aerobic respiration
E	0045275	cellular_component	respiratory chain complex III
E	0045333	biological_process	cellular respiration
E	0046872	molecular_function	metal ion binding
E	1902600	biological_process	proton transmembrane transport
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005886	cellular_component	plasma membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0006412	biological_process	translation
F	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
F	0009060	biological_process	aerobic respiration
F	0045275	cellular_component	respiratory chain complex III
F	0045333	biological_process	cellular respiration
F	1902600	biological_process	proton transmembrane transport
G	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005886	cellular_component	plasma membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0006412	biological_process	translation
G	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
G	0009060	biological_process	aerobic respiration
G	0010570	biological_process	regulation of filamentous growth
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0045275	cellular_component	respiratory chain complex III
G	0045333	biological_process	cellular respiration
G	0099617	cellular_component	matrix side of mitochondrial inner membrane
G	1902600	biological_process	proton transmembrane transport
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H	0006412	biological_process	translation
H	0045275	cellular_component	respiratory chain complex III
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005886	cellular_component	plasma membrane
I	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0006412	biological_process	translation
I	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
I	0009060	biological_process	aerobic respiration
I	0034551	biological_process	mitochondrial respiratory chain complex III assembly
I	0045275	cellular_component	respiratory chain complex III
I	0045333	biological_process	cellular respiration
I	1902600	biological_process	proton transmembrane transport
K	0000792	cellular_component	heterochromatin
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
K	0009055	molecular_function	electron transfer activity
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0022904	biological_process	respiratory electron transport chain
K	0045275	cellular_component	respiratory chain complex III
K	0046872	molecular_function	metal ion binding
K	1902600	biological_process	proton transmembrane transport
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005886	cellular_component	plasma membrane
L	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
L	0006412	biological_process	translation
L	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
L	0009060	biological_process	aerobic respiration
L	0016020	cellular_component	membrane
L	0030061	cellular_component	mitochondrial crista
L	0045275	cellular_component	respiratory chain complex III
L	0045333	biological_process	cellular respiration
L	0046872	molecular_function	metal ion binding
L	1902600	biological_process	proton transmembrane transport
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005886	cellular_component	plasma membrane
M	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
M	0006412	biological_process	translation
M	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
M	0009060	biological_process	aerobic respiration
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0045275	cellular_component	respiratory chain complex III
M	0045333	biological_process	cellular respiration
M	0046872	molecular_function	metal ion binding
M	0051537	molecular_function	2 iron, 2 sulfur cluster binding
M	1902600	biological_process	proton transmembrane transport
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005886	cellular_component	plasma membrane
N	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
N	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
N	0009055	molecular_function	electron transfer activity
N	0020037	molecular_function	heme binding
N	0045275	cellular_component	respiratory chain complex III
N	0045333	biological_process	cellular respiration
N	0046872	molecular_function	metal ion binding
N	1902600	biological_process	proton transmembrane transport
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005886	cellular_component	plasma membrane
O	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
O	0006412	biological_process	translation
O	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
O	0009060	biological_process	aerobic respiration
O	0045275	cellular_component	respiratory chain complex III
O	0045333	biological_process	cellular respiration
O	1902600	biological_process	proton transmembrane transport
P	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005886	cellular_component	plasma membrane
P	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P	0006412	biological_process	translation
P	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
P	0009060	biological_process	aerobic respiration
P	0010570	biological_process	regulation of filamentous growth
P	0034551	biological_process	mitochondrial respiratory chain complex III assembly
P	0045275	cellular_component	respiratory chain complex III
P	0045333	biological_process	cellular respiration
P	0099617	cellular_component	matrix side of mitochondrial inner membrane
P	1902600	biological_process	proton transmembrane transport
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Q	0006412	biological_process	translation
Q	0045275	cellular_component	respiratory chain complex III
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005886	cellular_component	plasma membrane
R	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R	0006412	biological_process	translation
R	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
R	0009060	biological_process	aerobic respiration
R	0034551	biological_process	mitochondrial respiratory chain complex III assembly
R	0045275	cellular_component	respiratory chain complex III
R	0045333	biological_process	cellular respiration
R	1902600	biological_process	proton transmembrane transport
T	0000792	cellular_component	heterochromatin
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
T	0009055	molecular_function	electron transfer activity
T	0016020	cellular_component	membrane
T	0016491	molecular_function	oxidoreductase activity
T	0022904	biological_process	respiratory electron transport chain
T	0045275	cellular_component	respiratory chain complex III
T	0046872	molecular_function	metal ion binding
T	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. ADEL

Chain	Residue	Details
B	ALA371-LEU374

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	34
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000250\|UniProtKB:P08067

Chain	Residue	Details
C	SER30-GLN47
M	SER30-GLN47
N	SER12-TYR34
N	TRP250-VAL268

site_id	SWS_FT_FI2
Number of Residues	58
Details	TRANSMEM: Helical => ECO:0000250\|UniProtKB:P08067

Chain	Residue	Details
C	GLY48-SER77
M	GLY48-SER77
N	CYS82
N	CYS85
T	GLY85-SER105
T	ILE116-TYR136
T	LEU151-VAL171
T	PHE179-MET199

site_id	SWS_FT_FI3
Number of Residues	270
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000250\|UniProtKB:P08067

Chain	Residue	Details
C	SER78-GLY213
M	SER78-GLY213

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00628

Chain	Residue	Details
C	CYS156
C	HIS158
C	CYS175
C	HIS178
M	CYS156
M	HIS158
M	CYS175
M	HIS178

site_id	SWS_FT_FI5
Number of Residues	8
Details	BINDING: axial binding residue => ECO:0000255\|PROSITE-ProRule:PRU00968

Chain	Residue	Details
K	HIS82
K	HIS96
K	HIS183
K	HIS197
T	HIS82
T	HIS96
T	HIS183
T	HIS197

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)