Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7RJA

Complex III2 from Candida albicans, inhibitor free

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0005575	cellular_component	cellular_component
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
A	0008121	molecular_function	quinol-cytochrome-c reductase activity
A	0008150	biological_process	biological_process
A	0009060	biological_process	aerobic respiration
A	0017087	cellular_component	mitochondrial processing peptidase complex
A	0022904	biological_process	respiratory electron transport chain
A	0045275	cellular_component	respiratory chain complex III
A	0045333	biological_process	cellular respiration
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005886	cellular_component	plasma membrane
B	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B	0008121	molecular_function	quinol-cytochrome-c reductase activity
B	0008150	biological_process	biological_process
B	0009060	biological_process	aerobic respiration
B	0016020	cellular_component	membrane
B	0022904	biological_process	respiratory electron transport chain
B	0030061	cellular_component	mitochondrial crista
B	0045275	cellular_component	respiratory chain complex III
B	0045333	biological_process	cellular respiration
B	0046872	molecular_function	metal ion binding
B	1902600	biological_process	proton transmembrane transport
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005886	cellular_component	plasma membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0008121	molecular_function	quinol-cytochrome-c reductase activity
C	0008150	biological_process	biological_process
C	0009060	biological_process	aerobic respiration
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0022904	biological_process	respiratory electron transport chain
C	0045275	cellular_component	respiratory chain complex III
C	0045333	biological_process	cellular respiration
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	1902600	biological_process	proton transmembrane transport
D	0005743	cellular_component	mitochondrial inner membrane
D	0005886	cellular_component	plasma membrane
D	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D	0008121	molecular_function	quinol-cytochrome-c reductase activity
D	0008150	biological_process	biological_process
D	0009055	molecular_function	electron transfer activity
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
D	0022904	biological_process	respiratory electron transport chain
D	0045275	cellular_component	respiratory chain complex III
D	0045333	biological_process	cellular respiration
D	0046872	molecular_function	metal ion binding
D	1902600	biological_process	proton transmembrane transport
F	0003674	molecular_function	molecular_function
F	0005743	cellular_component	mitochondrial inner membrane
F	0005886	cellular_component	plasma membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0008121	molecular_function	quinol-cytochrome-c reductase activity
F	0008150	biological_process	biological_process
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0022904	biological_process	respiratory electron transport chain
F	0045275	cellular_component	respiratory chain complex III
F	0045333	biological_process	cellular respiration
F	1902600	biological_process	proton transmembrane transport
G	0003674	molecular_function	molecular_function
G	0005743	cellular_component	mitochondrial inner membrane
G	0005886	cellular_component	plasma membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0008121	molecular_function	quinol-cytochrome-c reductase activity
G	0009060	biological_process	aerobic respiration
G	0010570	biological_process	regulation of filamentous growth
G	0016020	cellular_component	membrane
G	0022904	biological_process	respiratory electron transport chain
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0045275	cellular_component	respiratory chain complex III
G	0045333	biological_process	cellular respiration
G	0099617	cellular_component	matrix side of mitochondrial inner membrane
G	1902600	biological_process	proton transmembrane transport
H	0003674	molecular_function	molecular_function
H	0005575	cellular_component	cellular_component
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H	0008150	biological_process	biological_process
H	0016020	cellular_component	membrane
H	0022904	biological_process	respiratory electron transport chain
H	0045275	cellular_component	respiratory chain complex III
I	0003674	molecular_function	molecular_function
I	0005743	cellular_component	mitochondrial inner membrane
I	0005886	cellular_component	plasma membrane
I	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0008150	biological_process	biological_process
I	0016020	cellular_component	membrane
I	0022904	biological_process	respiratory electron transport chain
I	0045275	cellular_component	respiratory chain complex III
J	0004222	molecular_function	metalloendopeptidase activity
J	0005575	cellular_component	cellular_component
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
J	0008121	molecular_function	quinol-cytochrome-c reductase activity
J	0008150	biological_process	biological_process
J	0009060	biological_process	aerobic respiration
J	0017087	cellular_component	mitochondrial processing peptidase complex
J	0022904	biological_process	respiratory electron transport chain
J	0045275	cellular_component	respiratory chain complex III
J	0045333	biological_process	cellular respiration
J	0046872	molecular_function	metal ion binding
J	1902600	biological_process	proton transmembrane transport
K	0000792	cellular_component	heterochromatin
K	0005743	cellular_component	mitochondrial inner membrane
K	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K	0008121	molecular_function	quinol-cytochrome-c reductase activity
K	0009055	molecular_function	electron transfer activity
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0022904	biological_process	respiratory electron transport chain
K	0045275	cellular_component	respiratory chain complex III
K	0046872	molecular_function	metal ion binding
K	1902600	biological_process	proton transmembrane transport
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005886	cellular_component	plasma membrane
L	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
L	0008121	molecular_function	quinol-cytochrome-c reductase activity
L	0008150	biological_process	biological_process
L	0009060	biological_process	aerobic respiration
L	0016020	cellular_component	membrane
L	0022904	biological_process	respiratory electron transport chain
L	0030061	cellular_component	mitochondrial crista
L	0045275	cellular_component	respiratory chain complex III
L	0045333	biological_process	cellular respiration
L	0046872	molecular_function	metal ion binding
L	1902600	biological_process	proton transmembrane transport
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005886	cellular_component	plasma membrane
M	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
M	0008121	molecular_function	quinol-cytochrome-c reductase activity
M	0008150	biological_process	biological_process
M	0009060	biological_process	aerobic respiration
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0022904	biological_process	respiratory electron transport chain
M	0045275	cellular_component	respiratory chain complex III
M	0045333	biological_process	cellular respiration
M	0046872	molecular_function	metal ion binding
M	0051536	molecular_function	iron-sulfur cluster binding
M	0051537	molecular_function	2 iron, 2 sulfur cluster binding
M	1902600	biological_process	proton transmembrane transport
N	0005743	cellular_component	mitochondrial inner membrane
N	0005886	cellular_component	plasma membrane
N	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
N	0008121	molecular_function	quinol-cytochrome-c reductase activity
N	0008150	biological_process	biological_process
N	0009055	molecular_function	electron transfer activity
N	0016020	cellular_component	membrane
N	0020037	molecular_function	heme binding
N	0022904	biological_process	respiratory electron transport chain
N	0045275	cellular_component	respiratory chain complex III
N	0045333	biological_process	cellular respiration
N	0046872	molecular_function	metal ion binding
N	1902600	biological_process	proton transmembrane transport
P	0003674	molecular_function	molecular_function
P	0005743	cellular_component	mitochondrial inner membrane
P	0005886	cellular_component	plasma membrane
P	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P	0008121	molecular_function	quinol-cytochrome-c reductase activity
P	0008150	biological_process	biological_process
P	0009060	biological_process	aerobic respiration
P	0016020	cellular_component	membrane
P	0022904	biological_process	respiratory electron transport chain
P	0045275	cellular_component	respiratory chain complex III
P	0045333	biological_process	cellular respiration
P	1902600	biological_process	proton transmembrane transport
Q	0003674	molecular_function	molecular_function
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005886	cellular_component	plasma membrane
Q	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Q	0008121	molecular_function	quinol-cytochrome-c reductase activity
Q	0009060	biological_process	aerobic respiration
Q	0010570	biological_process	regulation of filamentous growth
Q	0016020	cellular_component	membrane
Q	0022904	biological_process	respiratory electron transport chain
Q	0034551	biological_process	mitochondrial respiratory chain complex III assembly
Q	0045275	cellular_component	respiratory chain complex III
Q	0045333	biological_process	cellular respiration
Q	0099617	cellular_component	matrix side of mitochondrial inner membrane
Q	1902600	biological_process	proton transmembrane transport
R	0003674	molecular_function	molecular_function
R	0005575	cellular_component	cellular_component
R	0005743	cellular_component	mitochondrial inner membrane
R	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R	0008150	biological_process	biological_process
R	0016020	cellular_component	membrane
R	0022904	biological_process	respiratory electron transport chain
R	0045275	cellular_component	respiratory chain complex III
S	0003674	molecular_function	molecular_function
S	0005743	cellular_component	mitochondrial inner membrane
S	0005886	cellular_component	plasma membrane
S	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S	0008150	biological_process	biological_process
S	0016020	cellular_component	membrane
S	0022904	biological_process	respiratory electron transport chain
S	0045275	cellular_component	respiratory chain complex III
T	0000792	cellular_component	heterochromatin
T	0005743	cellular_component	mitochondrial inner membrane
T	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T	0008121	molecular_function	quinol-cytochrome-c reductase activity
T	0009055	molecular_function	electron transfer activity
T	0016020	cellular_component	membrane
T	0016491	molecular_function	oxidoreductase activity
T	0022904	biological_process	respiratory electron transport chain
T	0045275	cellular_component	respiratory chain complex III
T	0046872	molecular_function	metal ion binding
T	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. ADEL

Chain	Residue	Details
B	ALA371-LEU374

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	160
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	40
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00967","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	120
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00967","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	70
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	306
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	54
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	20
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	58
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"P08067","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	190
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)