7RJ4

Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016032	biological_process	viral process
B	0016032	biological_process	viral process
C	0016032	biological_process	viral process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	114
Details	Region: {"description":"Interaction with human PPIA/CYPA and NUP153","evidences":[{"source":"PubMed","id":"24130490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8980234","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	24
Details	Region: {"description":"PPIA/CYPA-binding loop","evidences":[{"source":"UniProtKB","id":"P04591","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine; by host MAPK1","evidences":[{"source":"PubMed","id":"24509437","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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