Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7QHM

Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (stigmatellin and azide bound)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005886	cellular_component	plasma membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0022904	biological_process	respiratory electron transport chain
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
B	0005886	cellular_component	plasma membrane
B	0008121	molecular_function	quinol-cytochrome-c reductase activity
B	0009055	molecular_function	electron transfer activity
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0022904	biological_process	respiratory electron transport chain
B	0046872	molecular_function	metal ion binding
B	1902600	biological_process	proton transmembrane transport
C	0005506	molecular_function	iron ion binding
C	0005886	cellular_component	plasma membrane
C	0008121	molecular_function	quinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0016020	cellular_component	membrane
C	0020037	molecular_function	heme binding
C	0022904	biological_process	respiratory electron transport chain
C	0046872	molecular_function	metal ion binding
C	1902600	biological_process	proton transmembrane transport
D	0004129	molecular_function	cytochrome-c oxidase activity
D	0005886	cellular_component	plasma membrane
D	0006119	biological_process	oxidative phosphorylation
D	0009060	biological_process	aerobic respiration
D	0015990	biological_process	electron transport coupled proton transport
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
D	0022904	biological_process	respiratory electron transport chain
D	0046872	molecular_function	metal ion binding
E	0004129	molecular_function	cytochrome-c oxidase activity
E	0005507	molecular_function	copper ion binding
E	0005886	cellular_component	plasma membrane
E	0016020	cellular_component	membrane
E	0022900	biological_process	electron transport chain
E	0022904	biological_process	respiratory electron transport chain
E	0042773	biological_process	ATP synthesis coupled electron transport
E	0046872	molecular_function	metal ion binding
E	1902600	biological_process	proton transmembrane transport
F	0004129	molecular_function	cytochrome-c oxidase activity
F	0005886	cellular_component	plasma membrane
F	0009055	molecular_function	electron transfer activity
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0019646	biological_process	aerobic electron transport chain
F	0022904	biological_process	respiratory electron transport chain
F	1902600	biological_process	proton transmembrane transport
G	0004129	molecular_function	cytochrome-c oxidase activity
G	0005886	cellular_component	plasma membrane
G	0016020	cellular_component	membrane
G	0022900	biological_process	electron transport chain
G	1902600	biological_process	proton transmembrane transport
I	0005886	cellular_component	plasma membrane
M	0005886	cellular_component	plasma membrane
M	0009228	biological_process	thiamine biosynthetic process
N	0004497	molecular_function	monooxygenase activity
N	0005886	cellular_component	plasma membrane
N	0016491	molecular_function	oxidoreductase activity
N	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
N	0022904	biological_process	respiratory electron transport chain
N	0046872	molecular_function	metal ion binding
N	0051536	molecular_function	iron-sulfur cluster binding
N	0051537	molecular_function	2 iron, 2 sulfur cluster binding
O	0005886	cellular_component	plasma membrane
O	0008121	molecular_function	quinol-cytochrome-c reductase activity
O	0009055	molecular_function	electron transfer activity
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0022904	biological_process	respiratory electron transport chain
O	0046872	molecular_function	metal ion binding
O	1902600	biological_process	proton transmembrane transport
P	0005506	molecular_function	iron ion binding
P	0005886	cellular_component	plasma membrane
P	0008121	molecular_function	quinol-cytochrome-c reductase activity
P	0009055	molecular_function	electron transfer activity
P	0016020	cellular_component	membrane
P	0020037	molecular_function	heme binding
P	0022904	biological_process	respiratory electron transport chain
P	0046872	molecular_function	metal ion binding
P	1902600	biological_process	proton transmembrane transport
Q	0004129	molecular_function	cytochrome-c oxidase activity
Q	0005886	cellular_component	plasma membrane
Q	0006119	biological_process	oxidative phosphorylation
Q	0009060	biological_process	aerobic respiration
Q	0015990	biological_process	electron transport coupled proton transport
Q	0016020	cellular_component	membrane
Q	0020037	molecular_function	heme binding
Q	0022904	biological_process	respiratory electron transport chain
Q	0046872	molecular_function	metal ion binding
R	0004129	molecular_function	cytochrome-c oxidase activity
R	0005507	molecular_function	copper ion binding
R	0005886	cellular_component	plasma membrane
R	0016020	cellular_component	membrane
R	0022900	biological_process	electron transport chain
R	0022904	biological_process	respiratory electron transport chain
R	0042773	biological_process	ATP synthesis coupled electron transport
R	0046872	molecular_function	metal ion binding
R	1902600	biological_process	proton transmembrane transport
S	0004129	molecular_function	cytochrome-c oxidase activity
S	0005886	cellular_component	plasma membrane
S	0009055	molecular_function	electron transfer activity
S	0009060	biological_process	aerobic respiration
S	0016020	cellular_component	membrane
S	0019646	biological_process	aerobic electron transport chain
S	0022904	biological_process	respiratory electron transport chain
S	1902600	biological_process	proton transmembrane transport
T	0004129	molecular_function	cytochrome-c oxidase activity
T	0005886	cellular_component	plasma membrane
T	0016020	cellular_component	membrane
T	0022900	biological_process	electron transport chain
T	1902600	biological_process	proton transmembrane transport
V	0005886	cellular_component	plasma membrane
Z	0005886	cellular_component	plasma membrane
Z	0009228	biological_process	thiamine biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyvlalpffgivseiipvfsrkpmfgyvglifatlsigalsmavwa..HH

Chain	Residue	Details
D	TRP261-HIS315

site_id	PS00078
Number of Residues	55
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VaHsfwvpeflfkrdayahpeanksqrvfqieeiteegafvgrCaemCgtyHamM

Chain	Residue	Details
E	VAL242-MET296

site_id	PS00430
Number of Residues	69
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. csagqitqtssqvaavdgnqagsandpvlvrdvtvhlttdgeagvkftainqdtshtshtl......................................................ESVTVDGE

Chain	Residue	Details
H	CYS32-GLU100

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. FEISGLDP

Chain	Residue	Details
M	PHE86-PRO93

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1160
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	194
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11382224","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	360
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11382224","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	160
Details	Domain: {"description":"Cytochrome c 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	156
Details	Domain: {"description":"Cytochrome c 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"11382224","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11382224","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	6
Details	Binding site: {"description":"axial binding residue","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	4
Details	Cross-link: {"description":"1'-histidyl-3'-tyrosine (His-Tyr)","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	118
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	30
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	2
Details	Site: {"description":"Not N-palmitoylated","evidences":[{"source":"PubMed","id":"11577165","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	2
Details	Lipidation: {"description":"S-diacylglycerol cysteine","evidences":[{"source":"PubMed","id":"11577165","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	2
Details	Lipidation: {"description":"S-diacylglycerol cysteine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00303","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)