Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7QHM

Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (stigmatellin and azide bound)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0070469	cellular_component	respirasome
B	0005886	cellular_component	plasma membrane
B	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
B	0009055	molecular_function	electron transfer activity
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0022904	biological_process	respiratory electron transport chain
B	0046872	molecular_function	metal ion binding
B	0070469	cellular_component	respirasome
B	1902600	biological_process	proton transmembrane transport
C	0005506	molecular_function	iron ion binding
C	0005886	cellular_component	plasma membrane
C	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0016020	cellular_component	membrane
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0070469	cellular_component	respirasome
C	1902600	biological_process	proton transmembrane transport
D	0004129	molecular_function	cytochrome-c oxidase activity
D	0005886	cellular_component	plasma membrane
D	0006119	biological_process	oxidative phosphorylation
D	0009060	biological_process	aerobic respiration
D	0015990	biological_process	electron transport coupled proton transport
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
D	0070469	cellular_component	respirasome
E	0004129	molecular_function	cytochrome-c oxidase activity
E	0005507	molecular_function	copper ion binding
E	0005886	cellular_component	plasma membrane
E	0016020	cellular_component	membrane
E	0022900	biological_process	electron transport chain
E	0046872	molecular_function	metal ion binding
E	0070469	cellular_component	respirasome
E	1902600	biological_process	proton transmembrane transport
F	0004129	molecular_function	cytochrome-c oxidase activity
F	0005886	cellular_component	plasma membrane
F	0009055	molecular_function	electron transfer activity
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0019646	biological_process	aerobic electron transport chain
F	0022904	biological_process	respiratory electron transport chain
F	1902600	biological_process	proton transmembrane transport
G	0004129	molecular_function	cytochrome-c oxidase activity
G	0005886	cellular_component	plasma membrane
G	0016020	cellular_component	membrane
G	0022900	biological_process	electron transport chain
G	1902600	biological_process	proton transmembrane transport
I	0005886	cellular_component	plasma membrane
J	0016020	cellular_component	membrane
L	0016020	cellular_component	membrane
M	0005886	cellular_component	plasma membrane
M	0009228	biological_process	thiamine biosynthetic process
N	0005886	cellular_component	plasma membrane
N	0016491	molecular_function	oxidoreductase activity
N	0046872	molecular_function	metal ion binding
N	0051537	molecular_function	2 iron, 2 sulfur cluster binding
N	0070469	cellular_component	respirasome
O	0005886	cellular_component	plasma membrane
O	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
O	0009055	molecular_function	electron transfer activity
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0022904	biological_process	respiratory electron transport chain
O	0046872	molecular_function	metal ion binding
O	0070469	cellular_component	respirasome
O	1902600	biological_process	proton transmembrane transport
P	0005506	molecular_function	iron ion binding
P	0005886	cellular_component	plasma membrane
P	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
P	0009055	molecular_function	electron transfer activity
P	0016020	cellular_component	membrane
P	0020037	molecular_function	heme binding
P	0046872	molecular_function	metal ion binding
P	0070469	cellular_component	respirasome
P	1902600	biological_process	proton transmembrane transport
Q	0004129	molecular_function	cytochrome-c oxidase activity
Q	0005886	cellular_component	plasma membrane
Q	0006119	biological_process	oxidative phosphorylation
Q	0009060	biological_process	aerobic respiration
Q	0015990	biological_process	electron transport coupled proton transport
Q	0016020	cellular_component	membrane
Q	0020037	molecular_function	heme binding
Q	0046872	molecular_function	metal ion binding
Q	0070469	cellular_component	respirasome
R	0004129	molecular_function	cytochrome-c oxidase activity
R	0005507	molecular_function	copper ion binding
R	0005886	cellular_component	plasma membrane
R	0016020	cellular_component	membrane
R	0022900	biological_process	electron transport chain
R	0046872	molecular_function	metal ion binding
R	0070469	cellular_component	respirasome
R	1902600	biological_process	proton transmembrane transport
S	0004129	molecular_function	cytochrome-c oxidase activity
S	0005886	cellular_component	plasma membrane
S	0009055	molecular_function	electron transfer activity
S	0009060	biological_process	aerobic respiration
S	0016020	cellular_component	membrane
S	0019646	biological_process	aerobic electron transport chain
S	0022904	biological_process	respiratory electron transport chain
S	1902600	biological_process	proton transmembrane transport
T	0004129	molecular_function	cytochrome-c oxidase activity
T	0005886	cellular_component	plasma membrane
T	0016020	cellular_component	membrane
T	0022900	biological_process	electron transport chain
T	1902600	biological_process	proton transmembrane transport
V	0005886	cellular_component	plasma membrane
W	0016020	cellular_component	membrane
Y	0016020	cellular_component	membrane
Z	0005886	cellular_component	plasma membrane
Z	0009228	biological_process	thiamine biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyvlalpffgivseiipvfsrkpmfgyvglifatlsigalsmavwa..HH

Chain	Residue	Details
D	TRP261-HIS315

site_id	PS00078
Number of Residues	55
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VaHsfwvpeflfkrdayahpeanksqrvfqieeiteegafvgrCaemCgtyHamM

Chain	Residue	Details
E	VAL242-MET296

site_id	PS00430
Number of Residues	69
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. csagqitqtssqvaavdgnqagsandpvlvrdvtvhlttdgeagvkftainqdtshtshtl......................................................ESVTVDGE

Chain	Residue	Details
H	CYS32-GLU100

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. FEISGLDP

Chain	Residue	Details
M	PHE86-PRO93

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
I	THR35-HIS55
S	SER184-ILE204
D	ILE434-GLY454
D	ILE477-PHE497
Q	ILE43-ILE63
Q	VAL90-LEU110
Q	LEU122-LEU142
Q	MET171-LEU191
Q	ILE214-GLY234
Q	LEU259-VAL279
Q	PHE292-TRP312
I	ILE62-PRO82
Q	MET316-VAL336
Q	MET360-LEU380
Q	PHE399-PHE419
Q	ILE434-GLY454
Q	ILE477-PHE497
V	THR35-HIS55
V	ILE62-PRO82
T	LEU7-MET27
T	TRP40-LEU60
T	LEU86-LEU106
T	ALA107-PHE127
S	PHE142-VAL162

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
E	HIS244
R	CYS289
R	HIS293
R	MET296
E	CYS285
E	GLU287
E	CYS289
E	HIS293
E	MET296
R	HIS244
R	CYS285
R	GLU287

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Not N-palmitoylated => ECO:0000269\|PubMed:11577165

Chain	Residue	Details
E	CYS29
R	CYS29
D	HIS314
D	HIS315
Q	HIS265
Q	TYR269
Q	HIS314
Q	HIS315

site_id	SWS_FT_FI4
Number of Residues	2
Details	LIPID: S-diacylglycerol cysteine => ECO:0000269\|PubMed:11577165

Chain	Residue	Details
E	CYS29
R	CYS29
Q	HIS265
Q	TYR269

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)