7QHG

LIM domain kinase 2 (LIMK2) in complex with TH-470

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
B	0004672	molecular_function	protein kinase activity
B	0005524	molecular_function	ATP binding
B	0006468	biological_process	protein phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGFFGQAIkVthkatgkv..........MVMK

Chain	Residue	Details
A	LEU337-LYS360

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:22328514

Chain	Residue	Details
A	ASP451
B	ASP451

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	LEU337
A	LYS360
B	LEU337
B	LYS360

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine; by ROCK1 and CDC42BP => ECO:0000269|PubMed:11018042, ECO:0000269|PubMed:11340065

Chain	Residue	Details
A	THR505
B	THR505

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