7QBE
TC:CD320 in complex with nanobody TC-Nb11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006824 | biological_process | cobalt ion transport |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0015889 | biological_process | cobalamin transport |
| A | 0031419 | molecular_function | cobalamin binding |
| A | 0043202 | cellular_component | lysosomal lumen |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140104 | molecular_function | molecular carrier activity |
| A | 0140355 | molecular_function | cargo receptor ligand activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0006824 | biological_process | cobalt ion transport |
| C | 0009897 | cellular_component | external side of plasma membrane |
| C | 0015889 | biological_process | cobalamin transport |
| C | 0031419 | molecular_function | cobalamin binding |
| C | 0043202 | cellular_component | lysosomal lumen |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0140104 | molecular_function | molecular carrier activity |
| C | 0140355 | molecular_function | cargo receptor ligand activity |
Functional Information from PROSITE/UniProt
| site_id | PS00468 |
| Number of Residues | 14 |
| Details | COBALAMIN_BINDING Eukaryotic cobalamin-binding proteins signature. SVDTAAMAgLAFTC |
| Chain | Residue | Details |
| A | SER174-CYS187 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CVpltwr.CDrdlDCsdgsDEEe....C |
| Chain | Residue | Details |
| B | CYS67-CYS89 | |
| B | CYS145-CYS167 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16537422","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27411955","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BB5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16537422","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BB5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16537422","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 74 |
| Details | Domain: {"description":"LDL-receptor class A 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 74 |
| Details | Domain: {"description":"LDL-receptor class A 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27411955","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZRP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
