7Q41
Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of ubiquitin-protein ligase E3A (E6AP)
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 26 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGLGISSGTVpIprqitalssy........VVKK |
| Chain | Residue | Details |
| A | LEU3024-LYS3049 |
| site_id | PS00626 |
| Number of Residues | 11 |
| Details | RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. IACGsSHSAAL |
| Chain | Residue | Details |
| A | ILE3104-LEU3114 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 51 |
| Details | Repeat: {"description":"RCC1 2-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 162 |
| Details | Repeat: {"description":"RCC1 2-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 153 |
| Details | Repeat: {"description":"RCC1 2-3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 150 |
| Details | Repeat: {"description":"RCC1 2-4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 153 |
| Details | Repeat: {"description":"RCC1 2-5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 150 |
| Details | Repeat: {"description":"RCC1 2-6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 153 |
| Details | Repeat: {"description":"RCC1 2-7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00235","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2013","submissionDatabase":"PDB data bank","title":"Structure of the first RCC1-like domain of HERC2.","authors":["Tempel W.","Khan M.B.","Dong A.","Hu J.","Li Y.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Tong Y."]}}]} |
| Chain | Residue | Details |
