Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7Q00

Crystal structure of serine hydroxymethyltransferase, isoform 4 from Arabidopsis thaliana (SHM4)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004372molecular_functionglycine hydroxymethyltransferase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006730biological_processone-carbon metabolic process
A0007623biological_processcircadian rhythm
A0009506cellular_componentplasmodesma
A0016740molecular_functiontransferase activity
A0019264biological_processglycine biosynthetic process from serine
A0030170molecular_functionpyridoxal phosphate binding
A0035999biological_processtetrahydrofolate interconversion
A1901149molecular_functionsalicylic acid binding
B0004372molecular_functionglycine hydroxymethyltransferase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006730biological_processone-carbon metabolic process
B0007623biological_processcircadian rhythm
B0009506cellular_componentplasmodesma
B0016740molecular_functiontransferase activity
B0019264biological_processglycine biosynthetic process from serine
B0030170molecular_functionpyridoxal phosphate binding
B0035999biological_processtetrahydrofolate interconversion
B1901149molecular_functionsalicylic acid binding
C0004372molecular_functionglycine hydroxymethyltransferase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006730biological_processone-carbon metabolic process
C0007623biological_processcircadian rhythm
C0009506cellular_componentplasmodesma
C0016740molecular_functiontransferase activity
C0019264biological_processglycine biosynthetic process from serine
C0030170molecular_functionpyridoxal phosphate binding
C0035999biological_processtetrahydrofolate interconversion
C1901149molecular_functionsalicylic acid binding
D0004372molecular_functionglycine hydroxymethyltransferase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006730biological_processone-carbon metabolic process
D0007623biological_processcircadian rhythm
D0009506cellular_componentplasmodesma
D0016740molecular_functiontransferase activity
D0019264biological_processglycine biosynthetic process from serine
D0030170molecular_functionpyridoxal phosphate binding
D0035999biological_processtetrahydrofolate interconversion
D1901149molecular_functionsalicylic acid binding
Functional Information from PROSITE/UniProt
site_idPS00096
Number of Residues17
DetailsSHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DVvTTTTHKSLrGPRAG
ChainResidueDetails
AASP236-GLY252

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsBINDING: BINDING => ECO:0000269|PubMed:31873125, ECO:0007744|PDB:6SMR
ChainResidueDetails
ASER39
ATYR59
AGLU61
ASER105
AHIS134
ASER190
AHIS218
AGLY290
ALYS373
AARG389
BSER39
BTYR59
BGLU61
BSER105
BHIS134
BSER190
BHIS218
BGLY290
BLYS373
BARG389
CSER39
CTYR59
CGLU61
CSER105
CHIS134
CSER190
CHIS218
CGLY290
CLYS373
CARG389
DSER39
DTYR59
DGLU61
DSER105
DHIS134
DSER190
DHIS218
DGLY290
DLYS373
DARG389

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q94C74
ChainResidueDetails
ATYR69
ALLP244
BTYR69
BLLP244
CTYR69
CLLP244
DTYR69
DLLP244

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22223895
ChainResidueDetails
AMET1
BMET1
CMET1
DMET1

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250
ChainResidueDetails
ALLP244
BLLP244
CLLP244
DLLP244

219869

PDB entries from 2024-05-15

PDB statisticsPDBj update infoContact PDBjnumon