7PU5

Structure of SFPQ-NONO complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
J	0003676	molecular_function	nucleic acid binding
J	0003723	molecular_function	RNA binding
K	0003676	molecular_function	nucleic acid binding
K	0003723	molecular_function	RNA binding
L	0003676	molecular_function	nucleic acid binding
L	0003723	molecular_function	RNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: Phosphoserine; by MKNK2 => ECO:0000269|PubMed:17965020, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER283
D	SER283
F	SER283
H	SER283
J	SER283
L	SER283

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: Phosphotyrosine; by ALK => ECO:0000269|PubMed:17537995

Chain	Residue	Details
B	TYR293
D	TYR293
F	TYR293
H	TYR293
J	TYR293
L	TYR293

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: N6,N6-dimethyllysine => ECO:0000269|Ref.4

Chain	Residue	Details
B	LYS314
D	LYS314
F	LYS314
H	LYS314
J	LYS314
L	LYS314

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
B	LYS319
H	LYS319
H	LYS421
H	LYS472
J	LYS319
J	LYS421
J	LYS472
L	LYS319
L	LYS421
L	LYS472
B	LYS421
B	LYS472
D	LYS319
D	LYS421
D	LYS472
F	LYS319
F	LYS421
F	LYS472

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
B	LYS338
C	LYS96
C	LYS99
C	LYS126
C	LYS190
C	LYS243
C	LYS249
E	LYS60
E	LYS96
D	LYS338
E	LYS99
E	LYS126
E	LYS190
E	LYS243
E	LYS249
G	LYS60
G	LYS96
G	LYS99
G	LYS126
F	LYS338
G	LYS190
G	LYS243
G	LYS249
I	LYS60
I	LYS96
I	LYS99
I	LYS126
I	LYS190
I	LYS243
H	LYS338
I	LYS249
K	LYS60
K	LYS96
K	LYS99
K	LYS126
K	LYS190
K	LYS243
K	LYS249
J	LYS338
L	LYS338
A	LYS243
A	LYS249
C	LYS60

---

site_id	SWS_FT_FI6
Number of Residues	6
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	THR368
D	THR368
F	THR368
H	THR368
J	THR368
L	THR368

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER374
J	SER496
L	SER374
L	SER496
B	SER496
D	SER374
D	SER496
F	SER374
F	SER496
H	SER374
H	SER496
J	SER374

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
B	SER379
D	SER379
F	SER379
H	SER379
J	SER379
L	SER379

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
B	LYS279
D	LYS279
F	LYS279
H	LYS279
J	LYS279
L	LYS279

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
J	LYS338
L	LYS338
B	LYS338
D	LYS338
F	LYS338
H	LYS338

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