7PHU

PfRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005923	cellular_component	bicellular tight junction
A	0008201	molecular_function	heparin binding
A	0016020	cellular_component	membrane
A	0020002	cellular_component	host cell plasma membrane
A	0020008	cellular_component	rhoptry
A	0031410	cellular_component	cytoplasmic vesicle
A	0032991	cellular_component	protein-containing complex
A	0033644	cellular_component	host cell membrane
A	0034591	cellular_component	rhoptry lumen
A	0043655	cellular_component	host extracellular space
A	0044409	biological_process	symbiont entry into host
A	0044650	biological_process	adhesion of symbiont to host cell
A	0045177	cellular_component	apical part of cell
A	0046789	molecular_function	host cell surface receptor binding

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
B	TYR210-HIS216
C	TYR193-HIS199
E	TYR197-HIS203
D	TYR215-HIS221
D	PHE440-HIS446

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	SITE: Cleavage => ECO:0000269|PubMed:28186186

Chain	Residue	Details
A	LYS140

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	GLN38
A	ASN297

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:25296023, ECO:0007744|PDB:4WAT

Chain	Residue	Details
A	ASN214

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