7PAD
The crystal structure of DW-0254 in complex with PDE6D
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0005095 | molecular_function | GTPase inhibitor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005929 | cellular_component | cilium |
| B | 0007601 | biological_process | visual perception |
| B | 0016020 | cellular_component | membrane |
| B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
| B | 0031267 | molecular_function | small GTPase binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0042995 | cellular_component | cell projection |
| B | 0050953 | biological_process | sensory perception of light stimulus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue NI B 201 |
| Chain | Residue |
| B | SER2 |
| B | HOH340 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| B | TRP90 |
| B | PHE91 |
| B | GLU110 |
| B | HOH346 |
| B | HOH370 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue O7W B 203 |
| Chain | Residue |
| B | ILE53 |
| B | LEU63 |
| B | LEU76 |
| B | LEU87 |
| B | GLU88 |
| B | TRP90 |
| B | ALA111 |
| B | SER115 |
| B | ILE129 |
| B | LEU147 |
| B | TYR149 |
| B | HOH364 |
| B | MET20 |
| B | LEU22 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue EPE B 204 |
| Chain | Residue |
| B | PHE92 |
| B | GLU93 |
| B | PHE94 |
| B | TRP105 |
| B | GLN106 |
| B | SER107 |
| B | HOH317 |
| B | HOH319 |
| B | HOH320 |
| B | HOH330 |
| B | HOH371 |
