7P75
Re-engineered 2-deoxy-D-ribose-5-phosphate aldolase catalysing asymmetric Michael addition reactions in substrate-free state
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004139 | molecular_function | deoxyribose-phosphate aldolase activity |
| AAA | 0005737 | cellular_component | cytoplasm |
| AAA | 0005829 | cellular_component | cytosol |
| AAA | 0006018 | biological_process | 2-deoxyribose 1-phosphate catabolic process |
| AAA | 0006974 | biological_process | DNA damage response |
| AAA | 0009264 | biological_process | deoxyribonucleotide catabolic process |
| AAA | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| AAA | 0016020 | cellular_component | membrane |
| AAA | 0016052 | biological_process | carbohydrate catabolic process |
| AAA | 0016829 | molecular_function | lyase activity |
| AAA | 0046386 | biological_process | deoxyribose phosphate catabolic process |
| BBB | 0004139 | molecular_function | deoxyribose-phosphate aldolase activity |
| BBB | 0005737 | cellular_component | cytoplasm |
| BBB | 0005829 | cellular_component | cytosol |
| BBB | 0006018 | biological_process | 2-deoxyribose 1-phosphate catabolic process |
| BBB | 0006974 | biological_process | DNA damage response |
| BBB | 0009264 | biological_process | deoxyribonucleotide catabolic process |
| BBB | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| BBB | 0016020 | cellular_component | membrane |
| BBB | 0016052 | biological_process | carbohydrate catabolic process |
| BBB | 0016829 | molecular_function | lyase activity |
| BBB | 0046386 | biological_process | deoxyribose phosphate catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00592","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11598300","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with acetaldehyde","evidences":[{"source":"HAMAP-Rule","id":"MF_00592","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11598300","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15476818","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00592","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11598300","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"15476818","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
