7P5X

Mycobacterial RNAP with transcriptional activator PafBC

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AA	0000428	cellular_component	DNA-directed RNA polymerase complex
AA	0003677	molecular_function	DNA binding
AA	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
AA	0005737	cellular_component	cytoplasm
AA	0006351	biological_process	DNA-templated transcription
AA	0016779	molecular_function	nucleotidyltransferase activity
AA	0034062	molecular_function	5'-3' RNA polymerase activity
AA	0046983	molecular_function	protein dimerization activity
AB	0000428	cellular_component	DNA-directed RNA polymerase complex
AB	0003677	molecular_function	DNA binding
AB	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
AB	0005737	cellular_component	cytoplasm
AB	0006351	biological_process	DNA-templated transcription
AB	0016779	molecular_function	nucleotidyltransferase activity
AB	0034062	molecular_function	5'-3' RNA polymerase activity
AB	0046983	molecular_function	protein dimerization activity
AC	0000428	cellular_component	DNA-directed RNA polymerase complex
AC	0003677	molecular_function	DNA binding
AC	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
AC	0005515	molecular_function	protein binding
AC	0006351	biological_process	DNA-templated transcription
AC	0016779	molecular_function	nucleotidyltransferase activity
AC	0032549	molecular_function	ribonucleoside binding
AC	0034062	molecular_function	5'-3' RNA polymerase activity
AC	0046677	biological_process	response to antibiotic
AD	0000287	molecular_function	magnesium ion binding
AD	0000428	cellular_component	DNA-directed RNA polymerase complex
AD	0003677	molecular_function	DNA binding
AD	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
AD	0006351	biological_process	DNA-templated transcription
AD	0008270	molecular_function	zinc ion binding
AD	0016779	molecular_function	nucleotidyltransferase activity
AD	0034062	molecular_function	5'-3' RNA polymerase activity
AD	0046872	molecular_function	metal ion binding
AE	0000428	cellular_component	DNA-directed RNA polymerase complex
AE	0003677	molecular_function	DNA binding
AE	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
AE	0006351	biological_process	DNA-templated transcription
AE	0016779	molecular_function	nucleotidyltransferase activity
AE	0034062	molecular_function	5'-3' RNA polymerase activity
AF	0003677	molecular_function	DNA binding
AF	0003700	molecular_function	DNA-binding transcription factor activity
AF	0005737	cellular_component	cytoplasm
AF	0006352	biological_process	DNA-templated transcription initiation
AF	0006355	biological_process	regulation of DNA-templated transcription
AF	0010468	biological_process	regulation of gene expression
AF	0016987	molecular_function	sigma factor activity
AF	2000142	biological_process	regulation of DNA-templated transcription initiation
AJ	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
AJ	0045893	biological_process	positive regulation of DNA-templated transcription
AJ	0046677	biological_process	response to antibiotic

Functional Information from PROSITE/UniProt

site_id	PS00715
Number of Residues	14
Details	SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAV

Chain	Residue	Details
AF	ASP257-VAL270

---

site_id	PS00716
Number of Residues	27
Details	SIGMA70_2 Sigma-70 factors family signature 2. TldEIGqvygVTrerIrQIEsktMskL

Chain	Residue	Details
AF	THR426-LEU452

---

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL

Chain	Residue	Details
AF	LEU233-LEU240

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV

Chain	Residue	Details
AC	GLY873-VAL885

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01322

Chain	Residue	Details
AD	CYS60
AD	CYS974
AD	CYS977
AD	CYS62
AD	CYS75
AD	CYS78
AD	ASP535
AD	ASP537
AD	ASP539
AD	CYS890
AD	CYS967

---