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7P3S

Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 12

Functional Information from GO Data
ChainGOidnamespacecontents
A0004407molecular_functionhistone deacetylase activity
A0005634cellular_componentnucleus
A0031507biological_processheterochromatin formation
A0040029biological_processepigenetic regulation of gene expression
A0141221molecular_functionhistone deacetylase activity, hydrolytic mechanism
B0004407molecular_functionhistone deacetylase activity
B0005634cellular_componentnucleus
B0031507biological_processheterochromatin formation
B0040029biological_processepigenetic regulation of gene expression
B0141221molecular_functionhistone deacetylase activity, hydrolytic mechanism
C0004407molecular_functionhistone deacetylase activity
C0005634cellular_componentnucleus
C0031507biological_processheterochromatin formation
C0040029biological_processepigenetic regulation of gene expression
C0141221molecular_functionhistone deacetylase activity, hydrolytic mechanism
D0004407molecular_functionhistone deacetylase activity
D0005634cellular_componentnucleus
D0031507biological_processheterochromatin formation
D0040029biological_processepigenetic regulation of gene expression
D0141221molecular_functionhistone deacetylase activity, hydrolytic mechanism

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PDB entries from 2026-06-03

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