7P2V

Crystal structure of Schistosoma mansoni HDAC8 in complex with a 4-chlorophenyl-spiroindoline capped hydroxamate-based inhibitor, bound to a novel site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0004407	molecular_function	histone deacetylase activity
A	0005634	cellular_component	nucleus
A	0006338	biological_process	chromatin remodeling
A	0046872	molecular_function	metal ion binding