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7P2S

Crystal structure of Schistosoma mansoni HDAC8 in complex with a tricyclic thieno[3,2-b]indole capped hydroxamate-based inhibitor, chlorine derivative

Functional Information from GO Data
ChainGOidnamespacecontents
A0004407molecular_functionhistone deacetylase activity
A0005634cellular_componentnucleus
A0006325biological_processchromatin organization
A0031507biological_processheterochromatin formation
A0040029biological_processepigenetic regulation of gene expression
A0046872molecular_functionmetal ion binding

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PDB entries from 2025-06-18

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