7OW7

EIF6-bound large subunit of the human ribosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0005925	cellular_component	focal adhesion
D	0006412	biological_process	translation
D	0014069	cellular_component	postsynaptic density
D	0015934	cellular_component	large ribosomal subunit
D	0016020	cellular_component	membrane
D	0019843	molecular_function	rRNA binding
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	0022626	cellular_component	cytosolic ribosome
D	0045202	cellular_component	synapse
D	0098794	cellular_component	postsynapse
D	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005791	cellular_component	rough endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0005925	cellular_component	focal adhesion
F	0006412	biological_process	translation
F	0016020	cellular_component	membrane
F	0016604	cellular_component	nuclear body
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	0022626	cellular_component	cytosolic ribosome
F	0070062	cellular_component	extracellular exosome
F	1990904	cellular_component	ribonucleoprotein complex
G	0000027	biological_process	ribosomal large subunit assembly
G	0002181	biological_process	cytoplasmic translation
G	0003723	molecular_function	RNA binding
G	0003730	molecular_function	mRNA 3'-UTR binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0005925	cellular_component	focal adhesion
G	0006364	biological_process	rRNA processing
G	0006412	biological_process	translation
G	0008097	molecular_function	5S rRNA binding
G	0010628	biological_process	positive regulation of gene expression
G	0016020	cellular_component	membrane
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	0022626	cellular_component	cytosolic ribosome
G	0031625	molecular_function	ubiquitin protein ligase binding
G	0032991	cellular_component	protein-containing complex
G	0042273	biological_process	ribosomal large subunit biogenesis
G	0045727	biological_process	positive regulation of translation
G	0048027	molecular_function	mRNA 5'-UTR binding
G	0050821	biological_process	protein stabilization
G	0070062	cellular_component	extracellular exosome
G	1901796	biological_process	regulation of signal transduction by p53 class mediator
G	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
G	1990904	cellular_component	ribonucleoprotein complex
G	1990948	molecular_function	ubiquitin ligase inhibitor activity
G	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
G	2000435	biological_process	negative regulation of protein neddylation
H	0002181	biological_process	cytoplasmic translation
H	0003677	molecular_function	DNA binding
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005783	cellular_component	endoplasmic reticulum
H	0005791	cellular_component	rough endoplasmic reticulum
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0005925	cellular_component	focal adhesion
H	0006355	biological_process	regulation of DNA-templated transcription
H	0006412	biological_process	translation
H	0014069	cellular_component	postsynaptic density
H	0015934	cellular_component	large ribosomal subunit
H	0016020	cellular_component	membrane
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0022626	cellular_component	cytosolic ribosome
H	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
H	0045202	cellular_component	synapse
H	0045296	molecular_function	cadherin binding
H	1990904	cellular_component	ribonucleoprotein complex
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003729	molecular_function	mRNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005634	cellular_component	nucleus
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0006417	biological_process	regulation of translation
I	0015934	cellular_component	large ribosomal subunit
I	0016020	cellular_component	membrane
I	0017148	biological_process	negative regulation of translation
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0022626	cellular_component	cytosolic ribosome
I	0032496	biological_process	response to lipopolysaccharide
I	0032819	biological_process	positive regulation of natural killer cell proliferation
I	0042592	biological_process	homeostatic process
I	0045202	cellular_component	synapse
I	0048246	biological_process	macrophage chemotaxis
I	0060425	biological_process	lung morphogenesis
I	0071346	biological_process	cellular response to type II interferon
I	0097452	cellular_component	GAIT complex
I	1901194	biological_process	negative regulation of formation of translation preinitiation complex
I	1990904	cellular_component	ribonucleoprotein complex
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0022626	cellular_component	cytosolic ribosome
J	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0005791	cellular_component	rough endoplasmic reticulum
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0005925	cellular_component	focal adhesion
K	0006412	biological_process	translation
K	0016020	cellular_component	membrane
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0022626	cellular_component	cytosolic ribosome
K	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0005925	cellular_component	focal adhesion
L	0006412	biological_process	translation
L	0016020	cellular_component	membrane
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	0022626	cellular_component	cytosolic ribosome
L	0045202	cellular_component	synapse
L	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0014069	cellular_component	postsynaptic density
M	0016020	cellular_component	membrane
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0022626	cellular_component	cytosolic ribosome
M	1990904	cellular_component	ribonucleoprotein complex
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005783	cellular_component	endoplasmic reticulum
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0016020	cellular_component	membrane
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0022626	cellular_component	cytosolic ribosome
N	0045202	cellular_component	synapse
N	1990904	cellular_component	ribonucleoprotein complex
P	0000054	biological_process	ribosomal subunit export from nucleus
P	0000460	biological_process	maturation of 5.8S rRNA
P	0000470	biological_process	maturation of LSU-rRNA
P	0003743	molecular_function	translation initiation factor activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005638	cellular_component	lamin filament
P	0005654	cellular_component	nucleoplasm
P	0005730	cellular_component	nucleolus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005882	cellular_component	intermediate filament
P	0006110	biological_process	regulation of glycolytic process
P	0006412	biological_process	translation
P	0006413	biological_process	translational initiation
P	0032868	biological_process	response to insulin
P	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
P	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
P	0042254	biological_process	ribosome biogenesis
P	0042256	biological_process	cytosolic ribosome assembly
P	0042273	biological_process	ribosomal large subunit biogenesis
P	0042304	biological_process	regulation of fatty acid biosynthetic process
P	0043022	molecular_function	ribosome binding
P	0043023	molecular_function	ribosomal large subunit binding
P	0045202	cellular_component	synapse
P	0045652	biological_process	regulation of megakaryocyte differentiation
P	0045727	biological_process	positive regulation of translation
P	0070062	cellular_component	extracellular exosome
P	1902626	biological_process	assembly of large subunit precursor of preribosome
P	2000377	biological_process	regulation of reactive oxygen species metabolic process
Q	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Q	0001223	molecular_function	transcription coactivator binding
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005730	cellular_component	nucleolus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0005925	cellular_component	focal adhesion
Q	0006412	biological_process	translation
Q	0006610	biological_process	ribosomal protein import into nucleus
Q	0008284	biological_process	positive regulation of cell population proliferation
Q	0010628	biological_process	positive regulation of gene expression
Q	0015934	cellular_component	large ribosomal subunit
Q	0016020	cellular_component	membrane
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0022626	cellular_component	cytosolic ribosome
Q	0031625	molecular_function	ubiquitin protein ligase binding
Q	0032986	biological_process	protein-DNA complex disassembly
Q	0032991	cellular_component	protein-containing complex
Q	0045202	cellular_component	synapse
Q	0050821	biological_process	protein stabilization
Q	0070062	cellular_component	extracellular exosome
Q	0070180	molecular_function	large ribosomal subunit rRNA binding
Q	0070314	biological_process	G1 to G0 transition
Q	0072717	biological_process	cellular response to actinomycin D
Q	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
Q	1903450	biological_process	regulation of G1 to G0 transition
Q	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
Q	1990904	cellular_component	ribonucleoprotein complex
Q	1990948	molecular_function	ubiquitin ligase inhibitor activity
Q	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0022626	cellular_component	cytosolic ribosome
R	0045296	molecular_function	cadherin binding
R	0070062	cellular_component	extracellular exosome
R	1904841	molecular_function	TORC2 complex binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005654	cellular_component	nucleoplasm
S	0005730	cellular_component	nucleolus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006364	biological_process	rRNA processing
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0016020	cellular_component	membrane
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0022626	cellular_component	cytosolic ribosome
S	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
S	0034644	biological_process	cellular response to UV
S	0042273	biological_process	ribosomal large subunit biogenesis
S	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
S	0045727	biological_process	positive regulation of translation
S	0048027	molecular_function	mRNA 5'-UTR binding
S	0070062	cellular_component	extracellular exosome
S	0071480	biological_process	cellular response to gamma radiation
S	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
S	1904803	biological_process	regulation of translation involved in cellular response to UV
S	1990904	cellular_component	ribonucleoprotein complex
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0005737	cellular_component	cytoplasm
T	0005783	cellular_component	endoplasmic reticulum
T	0005791	cellular_component	rough endoplasmic reticulum
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0005925	cellular_component	focal adhesion
T	0006364	biological_process	rRNA processing
T	0006412	biological_process	translation
T	0016020	cellular_component	membrane
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	0022626	cellular_component	cytosolic ribosome
T	0045202	cellular_component	synapse
T	0070062	cellular_component	extracellular exosome
T	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005783	cellular_component	endoplasmic reticulum
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015934	cellular_component	large ribosomal subunit
U	0016020	cellular_component	membrane
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0045202	cellular_component	synapse
U	1990904	cellular_component	ribonucleoprotein complex
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0007566	biological_process	embryo implantation
V	0008201	molecular_function	heparin binding
V	0016020	cellular_component	membrane
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0045296	molecular_function	cadherin binding
V	1990904	cellular_component	ribonucleoprotein complex
W	0002181	biological_process	cytoplasmic translation
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0005925	cellular_component	focal adhesion
W	0006412	biological_process	translation
W	0014069	cellular_component	postsynaptic density
W	0016020	cellular_component	membrane
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	0022626	cellular_component	cytosolic ribosome
W	0031640	biological_process	killing of cells of another organism
W	0045202	cellular_component	synapse
W	0050829	biological_process	defense response to Gram-negative bacterium
W	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
W	0070062	cellular_component	extracellular exosome
W	1990904	cellular_component	ribonucleoprotein complex
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0005925	cellular_component	focal adhesion
X	0006412	biological_process	translation
X	0015934	cellular_component	large ribosomal subunit
X	0016020	cellular_component	membrane
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	0022626	cellular_component	cytosolic ribosome
X	0045202	cellular_component	synapse
X	0070062	cellular_component	extracellular exosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0016020	cellular_component	membrane
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000049	molecular_function	tRNA binding
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0016020	cellular_component	membrane
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0042273	biological_process	ribosomal large subunit biogenesis
Z	0045202	cellular_component	synapse
Z	0070062	cellular_component	extracellular exosome
Z	1990904	cellular_component	ribonucleoprotein complex
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005783	cellular_component	endoplasmic reticulum
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0022626	cellular_component	cytosolic ribosome
a	0045202	cellular_component	synapse
a	0045296	molecular_function	cadherin binding
a	0070062	cellular_component	extracellular exosome
a	1990904	cellular_component	ribonucleoprotein complex
b	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003729	molecular_function	mRNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005730	cellular_component	nucleolus
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0015934	cellular_component	large ribosomal subunit
b	0016020	cellular_component	membrane
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0022626	cellular_component	cytosolic ribosome
b	1990904	cellular_component	ribonucleoprotein complex
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005730	cellular_component	nucleolus
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0016020	cellular_component	membrane
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0022626	cellular_component	cytosolic ribosome
c	0045202	cellular_component	synapse
c	1990904	cellular_component	ribonucleoprotein complex
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0019843	molecular_function	rRNA binding
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0045202	cellular_component	synapse
d	0046872	molecular_function	metal ion binding
d	0097371	molecular_function	MDM2/MDM4 family protein binding
d	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
d	1990904	cellular_component	ribonucleoprotein complex
d	1990948	molecular_function	ubiquitin ligase inhibitor activity
e	0001501	biological_process	skeletal system development
e	0001503	biological_process	ossification
e	0002181	biological_process	cytoplasmic translation
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005515	molecular_function	protein binding
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0005925	cellular_component	focal adhesion
e	0006412	biological_process	translation
e	0006417	biological_process	regulation of translation
e	0007605	biological_process	sensory perception of sound
e	0014069	cellular_component	postsynaptic density
e	0022618	biological_process	protein-RNA complex assembly
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0022626	cellular_component	cytosolic ribosome
e	0033291	cellular_component	eukaryotic 80S initiation complex
e	0034463	biological_process	90S preribosome assembly
e	0042474	biological_process	middle ear morphogenesis
e	0045202	cellular_component	synapse
e	0048318	biological_process	axial mesoderm development
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005737	cellular_component	cytoplasm
i	0005783	cellular_component	endoplasmic reticulum
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0005886	cellular_component	plasma membrane
i	0006412	biological_process	translation
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0022626	cellular_component	cytosolic ribosome
i	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005925	cellular_component	focal adhesion
j	0006412	biological_process	translation
j	0008270	molecular_function	zinc ion binding
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0022626	cellular_component	cytosolic ribosome
j	0045202	cellular_component	synapse
j	0046872	molecular_function	metal ion binding
j	0070062	cellular_component	extracellular exosome
j	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005515	molecular_function	protein binding
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0016020	cellular_component	membrane
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	0022626	cellular_component	cytosolic ribosome
k	0030425	cellular_component	dendrite
k	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
k	0044297	cellular_component	cell body
k	0045202	cellular_component	synapse
k	0070062	cellular_component	extracellular exosome
k	1990904	cellular_component	ribonucleoprotein complex
m	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
m	0002181	biological_process	cytoplasmic translation
m	0003677	molecular_function	DNA binding
m	0003723	molecular_function	RNA binding
m	0003729	molecular_function	mRNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005730	cellular_component	nucleolus
m	0005737	cellular_component	cytoplasm
m	0005783	cellular_component	endoplasmic reticulum
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0005925	cellular_component	focal adhesion
m	0006364	biological_process	rRNA processing
m	0006412	biological_process	translation
m	0014069	cellular_component	postsynaptic density
m	0016020	cellular_component	membrane
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	0022626	cellular_component	cytosolic ribosome
m	0042273	biological_process	ribosomal large subunit biogenesis
m	0042802	molecular_function	identical protein binding
m	1990904	cellular_component	ribonucleoprotein complex
n	0000470	biological_process	maturation of LSU-rRNA
n	0002181	biological_process	cytoplasmic translation
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005730	cellular_component	nucleolus
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0005925	cellular_component	focal adhesion
n	0006412	biological_process	translation
n	0016020	cellular_component	membrane
n	0022625	cellular_component	cytosolic large ribosomal subunit
n	0022626	cellular_component	cytosolic ribosome
n	0042254	biological_process	ribosome biogenesis
n	0045202	cellular_component	synapse
n	0045296	molecular_function	cadherin binding
n	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0005925	cellular_component	focal adhesion
o	0006412	biological_process	translation
o	0016020	cellular_component	membrane
o	0019843	molecular_function	rRNA binding
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0022626	cellular_component	cytosolic ribosome
o	1990904	cellular_component	ribonucleoprotein complex
p	0000027	biological_process	ribosomal large subunit assembly
p	0003735	molecular_function	structural constituent of ribosome
p	0005634	cellular_component	nucleus
p	0005737	cellular_component	cytoplasm
p	0005783	cellular_component	endoplasmic reticulum
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0007141	biological_process	male meiosis I
p	0007283	biological_process	spermatogenesis
p	0016020	cellular_component	membrane
p	0022625	cellular_component	cytosolic large ribosomal subunit
p	0030154	biological_process	cell differentiation
p	0051321	biological_process	meiotic cell cycle
p	1990904	cellular_component	ribonucleoprotein complex
q	0000027	biological_process	ribosomal large subunit assembly
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005730	cellular_component	nucleolus
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006364	biological_process	rRNA processing
q	0006412	biological_process	translation
q	0006605	biological_process	protein targeting
q	0008097	molecular_function	5S rRNA binding
q	0010628	biological_process	positive regulation of gene expression
q	0016020	cellular_component	membrane
q	0019843	molecular_function	rRNA binding
q	0022625	cellular_component	cytosolic large ribosomal subunit
q	0022626	cellular_component	cytosolic ribosome
q	0031625	molecular_function	ubiquitin protein ligase binding
q	0032092	biological_process	positive regulation of protein binding
q	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
q	0032991	cellular_component	protein-containing complex
q	0034504	biological_process	protein localization to nucleus
q	0042273	biological_process	ribosomal large subunit biogenesis
q	0050821	biological_process	protein stabilization
q	0070062	cellular_component	extracellular exosome
q	1901796	biological_process	regulation of signal transduction by p53 class mediator
q	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
q	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
q	1990904	cellular_component	ribonucleoprotein complex
q	1990948	molecular_function	ubiquitin ligase inhibitor activity
q	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
q	2000435	biological_process	negative regulation of protein neddylation
r	0001824	biological_process	blastocyst development
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005730	cellular_component	nucleolus
r	0005737	cellular_component	cytoplasm
r	0005783	cellular_component	endoplasmic reticulum
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0016020	cellular_component	membrane
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	0022626	cellular_component	cytosolic ribosome
r	0045202	cellular_component	synapse
r	0060348	biological_process	bone development
r	1990904	cellular_component	ribonucleoprotein complex
s	0003723	molecular_function	RNA binding
s	0003735	molecular_function	structural constituent of ribosome
s	0005515	molecular_function	protein binding
s	0005737	cellular_component	cytoplasm
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0015934	cellular_component	large ribosomal subunit
s	1990904	cellular_component	ribonucleoprotein complex
t	0002181	biological_process	cytoplasmic translation
t	0003723	molecular_function	RNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0022625	cellular_component	cytosolic large ribosomal subunit
t	0022626	cellular_component	cytosolic ribosome
t	0044391	cellular_component	ribosomal subunit
t	0045202	cellular_component	synapse
t	0045296	molecular_function	cadherin binding
t	1990904	cellular_component	ribonucleoprotein complex
u	0000027	biological_process	ribosomal large subunit assembly
u	0002181	biological_process	cytoplasmic translation
u	0003723	molecular_function	RNA binding
u	0003729	molecular_function	mRNA binding
u	0003735	molecular_function	structural constituent of ribosome
u	0005515	molecular_function	protein binding
u	0005737	cellular_component	cytoplasm
u	0005783	cellular_component	endoplasmic reticulum
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0010458	biological_process	exit from mitosis
u	0016020	cellular_component	membrane
u	0021554	biological_process	optic nerve development
u	0022625	cellular_component	cytosolic large ribosomal subunit
u	0022626	cellular_component	cytosolic ribosome
u	0031290	biological_process	retinal ganglion cell axon guidance
u	0045202	cellular_component	synapse
u	0045296	molecular_function	cadherin binding
u	0060041	biological_process	retina development in camera-type eye
u	0070062	cellular_component	extracellular exosome
u	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
Q	ALA79-ILE105

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
R	LYS134-VAL149

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
f	LYS30-ARG46

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
q	LEU40-THR56

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
J	ARG126-LEU150

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
D	PRO197-GLU208

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
E	PHE211-ARG234

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
U	LYS110-GLY141

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
L	GLN7-PRO26

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
b	LYS43-VAL57

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
Y	PHE20-GLY40

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
m	VAL108-ILE140

---

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
F	GLY15-VAL22

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
o	GLN163-LYS184

---

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
W	SER24-LEU48

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
I	VAL84-GLY107

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
F	ASN116-HIS142

---

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
W	GLU80-GLY100

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
u	PHE8-ASP25

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
d	GLY4-GLY23

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
n	CYS174-GLY191

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
r	ARG71-GLY85

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
Z	GLY72-PRO93

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
K	LYS49-MET66

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
T	GLY125-PHE136

---

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
S	ASP52-VAL70

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
X	VAL62-GLY76

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
a	THR15-ASN28

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
H	ASN182-LYS200

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
N	GLY37-GLY62

---

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
i	LYS61-CYS72

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
c	PRO52-LYS62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
t	ASP46-GLY69

---

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
p	ALA108-VAL129

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"(3S)-3-hydroxyhistidine","evidences":[{"source":"PubMed","id":"23103944","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	37
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	25
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P50878","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"Q9D8E6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	53
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N-acetylglycine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	7
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P47962","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P47911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17924679","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	11
Details	Repeat: {"description":"3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	11
Details	Repeat: {"description":"4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P14148","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	5
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P61314","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P19253","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by ZIPK/DAPK3","evidences":[{"source":"PubMed","id":"18995835","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	3
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P84099","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P62717","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	20
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"Citrulline","evidences":[{"source":"UniProtKB","id":"P62751","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62751","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	35
Details	Domain: {"description":"KOW"}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"12962325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62911","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"O55142","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D1R9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	18
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P49166","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	21
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"12962325","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Boldt K.","von Kriegsheim A.","Lilla S.","Lempens A.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O55135","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by CK1","evidences":[{"source":"HAMAP-Rule","id":"MF_03132","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12917340","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21084295","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyl glutamic acid","evidences":[{"source":"PubMed","id":"34314702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---